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Association of systemic immune-inflammation index with all-cause mortality in lung cancer patients undergoing radiotherapy: a retrospective cohort study

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Association of systemic immune-inflammation index with all-cause mortality in lung cancer patients undergoing radiotherapy: a retrospective cohort study

Jianwei Yang et al · Frontiers Media S.A · 2026 · ISSN 2234-943X

BackgroundThe systemic immune-inflammation index (SII) has emerged as a widely studied inflammatory biomarker reflecting the balance between host inflammatory and immune status, although evidence in lung cancer patients ...

LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng

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Clinical utility of the lactate-to-albumin ratio for predicting mortality in elderly severe acute pancreatitis

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Clinical utility of the lactate-to-albumin ratio for predicting mortality in elderly severe acute pancreatitis

Qingcheng Zhu et al · Frontiers Media S.A · 2026 · ISSN 2296-858X

BackgroundElderly patients with severe acute pancreatitis (SAP) have high mortality, yet reliable early risk stratification tools remain limited. The lactate-to-albumin ratio (LAR) has emerged as a potential prognostic b...

LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng

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Integrating machine learning and clinicopathological data to stratify survival risk in young women with localized breast cancer

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Integrating machine learning and clinicopathological data to stratify survival risk in young women with localized breast cancer

Bin Xu et al · Frontiers Media S.A · 2026 · ISSN 2296-858X

BackgroundYoung women with localized breast cancer represent a clinically distinct population with heterogeneous outcomes, yet age-specific prognostic models remain limited. Conventional risk stratification tools derived...

LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng

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Prognostic factors and survival outcomes in patients undergoing limb-sparing surgery for primary malignant bone tumors

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Prognostic factors and survival outcomes in patients undergoing limb-sparing surgery for primary malignant bone tumors

Chunan Zhong et al · Frontiers Media S.A · 2026 · ISSN 2234-943X

BackgroundPrimary malignant bone tumors are aggressive neoplasms that frequently affect adolescents and young adults. Limb-sparing surgery (LSS) has become the preferred surgical approach when oncologically feasible; how...

LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng

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Prognostic model for predicting recurrence-free survival in HBV-related hepatocellular carcinoma patients after combined treatment: a multicenter study

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Prognostic model for predicting recurrence-free survival in HBV-related hepatocellular carcinoma patients after combined treatment: a multicenter study

Bojun Liu et al · Frontiers Media S.A · 2026 · ISSN 2234-943X

IntroductionHepatocellular carcinoma (HCC) is a lethal malignancy, with hepatitis B virus (HBV) infection as its leading cause in China. Transarterial chemoembolization (TACE) combined with radiofrequency ablation (RFA) ...

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Superior long-term survival with acceptable safety of ATG/G-CSF–based haplo-HSCT with intensified BU+MEL/TT conditioning in CR Pediatric Non-DS–AMKL

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Superior long-term survival with acceptable safety of ATG/G-CSF–based haplo-HSCT with intensified BU+MEL/TT conditioning in CR Pediatric Non-DS–AMKL

Fei Pan et al · Frontiers Media S.A · 2026 · ISSN 2234-943X

BackgroundNon–Down syndrome acute megakaryoblastic leukemia (non–DS–AMKL) is a rare but high-risk subtype of pediatric AML with dismal outcomes. Allo-HSCT in first complete remission (CR1) is recommended as the pre...

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TyG-WHtR predicts incident type 2 diabetes mellitus in NAFLD: a 12-year prospective cohort study

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TyG-WHtR predicts incident type 2 diabetes mellitus in NAFLD: a 12-year prospective cohort study

Nan’nan Chen et al · Frontiers Media S.A · 2026 · ISSN 1664-2392

BackgroundMetabolic composite indices effectively predict type 2 diabetes mellitus (T2DM) in the general population. However, whether these indices retain predictive value in patients with nonalcoholic fatty liver diseas...

LCC LCC:Diseases of the endocrine glands. Clinical endocrinologyIdioma eng

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