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Ophiocordyceps sinensis (formerly known as Cordyceps sinensis), commonly referred to as “dongchongxiacao” in Chinese, is a valuable traditional Chinese medicine whose bioactive small molecules form the essential mate...

Peptide lipidation is widely employed to enhance the apparent biological performance of peptide-based systems by improving stability, membrane association, and systemic persistence. However, increased potency is often in...

Antimicrobial resistance represents a major global health challenge, particularly in the context of multidrug-resistant bacteria. Although conventional antibiotics and antimicrobial peptides (AMPs) both exert selective p...

Rational protein design has successfully enhanced the mechanical stability of biomaterials by optimizing the internal topology of force-bearing domains. However, current design strategies predominantly focus on isolated ...

IntroductionAntimicrobial resistance (AMR) is rising globally, particularly among the clinically important ESKAPE pathogens, a group of bacteria responsible for a large number of hospital-acquired infections and known fo...

Clear cell renal cell carcinoma (ccRCC) is the most prevalent subtype of kidney cancer; however, first-line therapeutic agents show limited efficacy in patients with advanced disease. Bioactive peptides have emerged as p...

IntroductionThe secretome derived from Mesenchymal Stem Cells (MSCs) have received significant attention as a promising tool in regenerative medicine. This “cell-free” strategy offers a promising alternative to stem ...