NODOVOX | Discovery

Cervical human papillomavirus: the therapeutic target of botanical drugs

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Cervical human papillomavirus: the therapeutic target of botanical drugs

Yan-Cai Tang et al · Frontiers Media S.A · 2026 · ISSN 1663-9812

Persistent cervical human papillomavirus (HPV) infection is the key biological event underlying high-grade squamous intraepithelial lesions, cervical cancer development, and recurrence risk. Botanical drugs and their bio...

LCC LCC:Therapeutics. PharmacologyIdioma eng

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Characteristics, accessibility and regional equity evaluation of pediatric medicines through National Drug Price Negotiation of China, 2017–2024

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Characteristics, accessibility and regional equity evaluation of pediatric medicines through National Drug Price Negotiation of China, 2017–2024

Xinyue Yuan et al · Frontiers Media S.A · 2026 · ISSN 1663-9812

ObjectivesSince its inception in 2017, China’s National Drug Price Negotiation (NDPN) has served as a crucial mechanism for the strategic procurement of innovative medicines, with pediatric medicines representing a key...

LCC LCC:Therapeutics. PharmacologyIdioma eng

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Artificial intelligence for small-molecule chemical probe design: why drug-centric models may not transfer cleanly

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Artificial intelligence for small-molecule chemical probe design: why drug-centric models may not transfer cleanly

Renzo Carlucci et al · Frontiers Media S.A · 2026 · ISSN 2674-0338

Artificial intelligence (AI) is increasingly used to design and optimize small molecules. However, most current workflows remain centered on drug-candidate objectives, such as potency, ADMET, and drug-likeness, rather th...

LCC LCC:Therapeutics. PharmacologyIdioma eng

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Decoding FGFR inhibitor sensitivity in cholangiocarcinoma with interpretable machine learning and cross-platform pharmacogenomic validation

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Decoding FGFR inhibitor sensitivity in cholangiocarcinoma with interpretable machine learning and cross-platform pharmacogenomic validation

Yading Xie et al · Frontiers Media S.A · 2026 · ISSN 1663-9812

BackgroundFibroblast growth factor receptor (FGFR) inhibitors (FGFRis) benefit selected cholangiocarcinoma (CHOL) patients, yet responses remain heterogeneous and are not fully explained by canonical FGFR alterations. Cl...

LCC LCC:Therapeutics. PharmacologyIdioma eng

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Meta-analysis of the effects of exercise intervention on physical health in individuals undergoing compulsory isolation

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Meta-analysis of the effects of exercise intervention on physical health in individuals undergoing compulsory isolation

Zhiyao Zhang et al · Frontiers Media S.A · 2026 · ISSN 1664-0640

BackgroundPhysical health is the basic indicator to evaluate the health of drug addicts after the process of drug rehabilitation. In order to better improve the deficiency degree of physical health of drug addicts, it is...

LCC TENDOlBzeWNoaWF0cnk~Idioma eng

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