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12 resultados encontrados.

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Efficacy and safety of tirofiban for acute ischemic stroke without large and medium vessel occlusion: a systematic review and meta-analysis
Artículo
Acceso abierto Artículo DOAJ
Efficacy and safety of tirofiban for acute ischemic stroke without large and medium vessel occlusion: a systematic review and meta-analysis
Jiaqi Jiao et al · Frontiers Media S.A · 2026 · ISSN 1664-2295
BackgroundEarly and effective intervention is crucial in the management of acute ischemic stroke (AIS) without large- or medium-vessel occlusion (non-LVO/MVO), which accounts for approximately 60–70% of all AIS cases. ...
LCC LCC:Neurology. Diseases of the nervous systemIdioma eng
Acceso abiertoRuta libre sin proxy. Acceso recomendado cuando no hay suscripción activa.
Open Access
Disponible en línea Ficha bibliográfica
Thermosonication of traditional poppy vinegar: modulation of biomolecules, phenolic profile, and antidiabetic potential in a functional fermented food
Artículo
Acceso abierto Artículo DOAJ
Thermosonication of traditional poppy vinegar: modulation of biomolecules, phenolic profile, and antidiabetic potential in a functional fermented food
Meryem Akhan et al · Frontiers Media S.A · 2026 · ISSN 2296-861X
Traditional poppy vinegar is a functional fermented food matrix enriched with diverse biomolecules that may contribute to metabolic health. In this study, the effects of thermosonication on the biomolecular profile, anti...
LCC LCC:Nutrition. Foods and food supplyIdioma eng
Acceso abiertoRuta libre sin proxy. Acceso recomendado cuando no hay suscripción activa.
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Genome-wide identification and functional dissection of the BES1 family reveals key regulators of alkali stress response in hemp
Artículo
Acceso abierto Artículo DOAJ
Genome-wide identification and functional dissection of the BES1 family reveals key regulators of alkali stress response in hemp
Zeyu Jiang et al · Frontiers Media S.A · 2026 · ISSN 1664-462X
Plants frequently encounter diverse abiotic stresses, which require precise transcriptional regulation to maintain basic survival plasticity. The BES1 transcription factor family, a key component of brassinosteroid (BR) ...
LCC TENDOlBsYW50IGN1bHR1cmU~Idioma eng
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Network-driven prioritization and functional phenotyping nominate TTC23 as a biomarker-informed target in chlorpromazine repurposing for glioblastoma
Artículo
Material complementario disponible Artículo DOAJ
Network-driven prioritization and functional phenotyping nominate TTC23 as a biomarker-informed target in chlorpromazine repurposing for glioblastoma
Jianqiang Hao et al · Frontiers Media S.A · 2026 · ISSN 1663-9812
BackgroundGlioblastoma (GBM) remains a lethal brain tumor with limited therapeutic options and near-universal recurrence. Drug repurposing offers a practical strategy, but pleiotropic compounds require systematic target ...
LCC LCC:Therapeutics. PharmacologyIdioma eng
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Predictive value of gut metabolites combined with neutrophil to platelet ratio for clinical functional outcome in acute ischemic stroke treated with endovascular therapy
Artículo
Acceso abierto Artículo DOAJ
Predictive value of gut metabolites combined with neutrophil to platelet ratio for clinical functional outcome in acute ischemic stroke treated with endovascular therapy
Rongrong Liu et al · Frontiers Media S.A · 2026 · ISSN 2296-861X
PurposeThis study aimed to investigate the associations between gut metabolites Trimethylamine N-Oxide (TMAO), the novel platelet-derived inflammatory ratio index neutrophil-to-platelet ratio (NPR), and the prognosis of ...
LCC LCC:Nutrition. Foods and food supplyIdioma eng
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Mapping fMRI research in disorders of consciousness: a bibliometric study
Artículo
Material complementario disponible Artículo DOAJ
Mapping fMRI research in disorders of consciousness: a bibliometric study
Xi-Chen Wang et al · Frontiers Media S.A · 2026 · ISSN 1664-2295
ObjectiveTo systematically map the evolution, academic network structure, and emergent research fronts of functional magnetic resonance imaging (fMRI) applications in prolonged disorders of consciousness (pDoC) through b...
LCC LCC:Neurology. Diseases of the nervous systemIdioma eng
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Association and attributable hospital costs of chronic pain with relevant geriatric sensitive diseases among the older adults
Artículo
Material complementario disponible Artículo DOAJ
Association and attributable hospital costs of chronic pain with relevant geriatric sensitive diseases among the older adults
Ting Chen et al · Frontiers Media S.A · 2026 · ISSN 2296-2565
BackgroundThe adverse impacts of chronic pain extend far beyond the physical sensation itself. Chronic pain, an age-related condition, exacerbates geriatric disease burden and drives a central sensitivity-neuropsychiatri...
LCC LCC:Public aspects of medicineIdioma eng
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Precuneus hyperexcitability mediates inflammatory-driven pain hypersensitivity following sleep disruption: a multimodal neuroimaging study
Artículo
Material complementario disponible Artículo DOAJ
Precuneus hyperexcitability mediates inflammatory-driven pain hypersensitivity following sleep disruption: a multimodal neuroimaging study
Chao Li et al · Frontiers Media S.A · 2026 · ISSN 1664-3224
BackgroundSleep disruption(SD) has been shown to amplify inflammatory signaling and promote pain hypersensitivity, but how inflammation interacts with brain functional alterations to drive pain sensitization remains uncl...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Prognostic factors and survival outcomes in patients undergoing limb-sparing surgery for primary malignant bone tumors
Artículo
Acceso abierto Artículo DOAJ
Prognostic factors and survival outcomes in patients undergoing limb-sparing surgery for primary malignant bone tumors
Chunan Zhong et al · Frontiers Media S.A · 2026 · ISSN 2234-943X
BackgroundPrimary malignant bone tumors are aggressive neoplasms that frequently affect adolescents and young adults. Limb-sparing surgery (LSS) has become the preferred surgical approach when oncologically feasible; how...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
Acceso abiertoRuta libre sin proxy. Acceso recomendado cuando no hay suscripción activa.
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Research trends and knowledge mapping of transcranial direct current stimulation in depression: a bibliometric study based on web of science, Scopus, and PubMed (2000-2025)
Artículo
Acceso abierto Artículo DOAJ
Research trends and knowledge mapping of transcranial direct current stimulation in depression: a bibliometric study based on web of science, Scopus, and PubMed (2000-2025)
Dongyu Feng et al · Frontiers Media S.A · 2026 · ISSN 1664-0640
BackgroundDepressive disorders are clinically heterogeneous and mechanistically complex psychiatric conditions. Transcranial direct current stimulation (tDCS), a key non-invasive neuromodulation technique, has expanded r...
LCC TENDOlBzeWNoaWF0cnk~Idioma eng
Acceso abiertoRuta libre sin proxy. Acceso recomendado cuando no hay suscripción activa.
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Heterogeneity in the association between gut microbiota and insomnia moderated by Parkinson’s disease status
Artículo
Acceso abierto Artículo DOAJ
Heterogeneity in the association between gut microbiota and insomnia moderated by Parkinson’s disease status
Sheng-Hsuan Lin et al · Frontiers Media S.A · 2026 · ISSN 2235-2988
IntroductionParkinson’s disease (PD) is frequently accompanied by insomnia, and emerging evidence suggests the gut microbiome may play a role. This study investigates gut microbiome differences associated with insomnia...
LCC TENDOk1pY3JvYmlvbG9neQ~~Idioma eng
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Development and internal validation of a machine learning model for predicting intracranial infection after spontaneous intracerebral hemorrhage: a two-center retrospective study
Artículo
Material complementario disponible Artículo DOAJ
Development and internal validation of a machine learning model for predicting intracranial infection after spontaneous intracerebral hemorrhage: a two-center retrospective study
Yizhao Lin et al · Frontiers Media S.A · 2026 · ISSN 1664-2295
BackgroundIntracranial infection (ICI) is a serious complication following spontaneous intracerebral hemorrhage (ICH) and is associated with prolonged intensive care, increased morbidity, and poor functional outcomes. Ea...
LCC LCC:Neurology. Diseases of the nervous systemIdioma eng
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