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Central nervous system (CNS) involvement by CLL is rare. We report a non-treated CLL patient with low-risk factors, but showed leptomeningeal involvement during/after neuroborreliosis and EBV meningitis. An 80-year-old w...

BackgroundCentral nervous system (CNS) relapse in acute lymphoblastic leukemia (ALL) may occur despite systemic remission and can present with isolated neuro-ophthalmologic symptoms. Early diagnosis may be challenging as...

Ferroptosis is a form of regulated cell death driven by iron-dependent lipid peroxidation, which plays a pivotal role in regulating the inflammatory-immune microenvironment of central nervous system (CNS) diseases. Mount...

BackgroundEarly and effective intervention is crucial in the management of acute ischemic stroke (AIS) without large- or medium-vessel occlusion (non-LVO/MVO), which accounts for approximately 60–70% of all AIS cases. ...

ObjectiveTo investigate the clinical features and serological characteristics of patients with primary Sjögren's syndrome (pSS) complicated with sensorimotor neuropathy (SMN), and to provide a reference for the clinical...

In the central nervous system (CNS), programmed cell death (PCD) of neurons, is precisely regulated by various biomolecules to maintain neuronal development, establish neural structures, and maintain CNS homeostasis. Und...

BackgroundMS and NMOSD are chronic demyelinating diseases related to demyelinating attacks on the central nervous system which limit quality of life and predisposes patients to developing anxiety and depression which, in...

BackgroundCurrent prognostic models for cerebral venous sinus thrombosis (CVST) inadequately predict long-term cognitive and functional outcomes, focusing primarily on survival. We aimed to develop and validate a simple,...

BackgroundIntracranial infection (ICI) is a serious complication following spontaneous intracerebral hemorrhage (ICH) and is associated with prolonged intensive care, increased morbidity, and poor functional outcomes. Ea...

External ventricular drain (EVD) placement is a standard neurosurgical procedure for cerebrospinal fluid diversion and intracranial pressure monitoring, yet conventional freehand techniques are associated with substantia...

Post-stroke cognitive impairment (PSCI) has garnered widespread attention due to its high incidence and its association with increased risk of stroke recurrence and mortality. Growing evidence indicates that early predic...

ObjectiveTo systematically map the evolution, academic network structure, and emergent research fronts of functional magnetic resonance imaging (fMRI) applications in prolonged disorders of consciousness (pDoC) through b...

IntroductionPolyarteritis nodosa (PAN) is a rare systemic necrotizing vasculitis affecting medium-sized vessels. While peripheral neuropathy occurs in 50–75% of patients, cranial nerve involvement is exceptionally rare...

Quality of life (Qol) results from a complex interplay of physical, mental, and social aspects. Traditional assessments of Qol may not adequately describe well-being in serious chronic illness such as in people with Park...

BackgroundStroke remains a leading cause of long-term disability worldwide. Acupuncture has been increasingly integrated into post-stroke rehabilitation programs, yet evidence regarding combined acupuncture protocols rem...

As the prevalence of chronic rhinosinusitis (CRS) and allergic rhinitis (AR) continues to rise worldwide, more and more patients are reporting a lower quality of life. In addition to causing common nasal symptoms such as...

ObjectiveTo investigate the prognostic value of blood pressure variability (BPV) combined with serum tau protein in patients with traumatic brain injury (TBI).MethodsA total of 205 TBI patients were prospectively enrolle...

BackgroundSubarachnoid hemorrhage (SAH) from ruptured intracranial aneurysms is a severe stroke subtype with a high mortality rate. Statins, noted for cholesterol-independent benefits, are being studied as potential trea...

ObjectivesCerebral edema (CED) significantly exacerbates mortality in patients with acute ischemic stroke (AIS) and can offset the benefits of endovascular therapy. Uric acid (UA) is recognized for its potential neuropro...

BackgroundPrevious Studies on prediction models for futile reperfusion after endovascular thrombectomy (EVT) in acute ischemic stroke (AIS) related to large vessel occlusion (LVO) have yielded inconsistent results. This ...

BackgroundDiscrepancies in symptom concerns and the perceived burden among individuals with Parkinson's disease (PD), their caregivers, and their physicians can hinder effective care.ObjectivesWe investigated differences...

Spinal cord injury (SCI) triggers a cascade of primary and secondary pathological events that culminate in the formation of glial and fibrotic scars, which constitute a major barrier to axonal regeneration and functional...

Carotid artery stenting (CAS) has emerged as an effective alternative to carotid endarterectomy for treating carotid artery stenosis, particularly in high-risk surgical patients. However, in-stent restenosis (ISR) remain...

Materias / palabras clave: artificial intelligence; global health; health disparities; low and mid income countries; neurological disorder; nueroimaging