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BackgroundImmune checkpoint inhibitors (ICIs) have transformed treatment of locally advanced gastric cancer (LAGC), yet response heterogeneity and immune-related adverse events (irAEs) remain major challenges. Systemic i...

Embodied therapies such as movement therapy have shown promise in enhancing emotional regulation, cognitive engagement, and physical rehabilitation. However, scalable and personalized delivery of such interventions remai...

ObjectiveCongenital Hypogonadotropic Hypogonadism (CHH) is a rare disease with an extremely low incidence, and the outcomes of fertility induction therapy in CHH patients exhibit significant interindividual heterogeneity...

Platelets play a crucial role in atherothrombosis, as demonstrated by the effectiveness of the antiplatelet agent aspirin (acetylsalicylic acid, ASA) in the secondary prevention of cardiovascular disease. Low-dose aspiri...

The introduction of immune checkpoint inhibitors (ICIs) has reshaped the therapeutic landscape of advanced non-small cell lung cancer. However, immune-related adverse events (irAEs), including rare cases of life-threaten...

Human induced pluripotent stem cells (iPSCs) are transforming adoptive cell therapy by combining unlimited self-renewal, broad differentiation potential, and high amenability to genome engineering. These attributes make ...

The rising concern of antimicrobial resistance, coupled with the continually challenging management of complicated diseases such as cancer, has provided momentum toward precision molecular medicine. This review provides ...

Pharmacogenetics has redefined the understanding of antidepressant response by demonstrating that genetic variability profoundly influences both drug efficacy and safety. This review synthesizes current evidence on the i...

Myasthenia gravis (MG) has traditionally been conceptualized as a peripheral autoimmune disorder primarily mediated by autoantibodies targeting the neuromuscular junction. However, this classical paradigm fails to adequa...

BackgroundYoung women with localized breast cancer represent a clinically distinct population with heterogeneous outcomes, yet age-specific prognostic models remain limited. Conventional risk stratification tools derived...

Post-transplant lymphoproliferative disorders (PTLD) represent a heterogeneous group of complications with rising complexity, particularly as EBV-negative forms are increasingly recognized in adult recipients. While earl...