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Unlike their normal counterparts, tumor cells exhibited highly variable CpG methylation levels in a large proportion of the genome, which can lead to malignant cell transformation through multiple pathways. This prompted...

T47D and IBH6 cells that overexpress RUNX2 show high levels of FGFR2 and FGF2, supporting the hypothesis that FGF2 increases RUNX2 and, in turn, RUNX2 increases FGF2, maintaining a positive loop. However, in these models...