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Spinocerebellar ataxia type 8, a debilitating neurological disease with no effective treatment, is caused by a CAG•CTG expansion mutation. In SCA8 mice, metformin decreases repeat-associated non-AUG proteins and neuroi...

Here, we identify a novel signaling pathway in which Rnd3 regulates the metastatic potential of lung cancer cells. Understanding this pathway could be leveraged to target metastatic disease. Rnd3 regulates cellular proce...