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Abstract Regulatory T cells (Tregs) are key contributors to maintaining immune system stability, and their impairment has been linked to the pathogenesis of Graves’ disease (GD). However, the precise molecular mechanis...

Abstract To access the effect of SIRT1 in cerebral infarction and to explore its mechanism of ferroptosis. Bioinformatic Analysis was used to discover the associations between Ferroptosis-Related Genes and Cerebral Infar...

Abstract Although papillary thyroid cancer (PTC) genetic research has advanced from identifying driver genes to investigating susceptibility loci and gene-environment interactions, data in Chinese populations remain limi...

Abstract Animal responses to fear cues are shaped by competing motivations such as hunger, access to mates and safety. In our previous work, wild mice (Apodemus spp.) showed little reaction to non-native predator scents....

Abstract The significant economic burden of colorectal cancer (CRC) necessitates the development of innovative therapeutic approaches. Interest in the gut microbiota’s role in CRC has increased. Capecitabine, as a chem...

Abstract Whole-genome sequencing (WGS) of morphology-selected sperm pools provides an exploratory approach for investigating genomic features associated with variable sperm quality. In this study, pooled DNA from 1500 in...

Abstract Certain human mutations in the mitochondrial aldehyde dehydrogenase 4A1 (ALDH4A1) lead to a severe, paediatric form of epilepsy and developmental abnormalities, yet the precise molecular mechanism leading to the...

Abstract The role of Bisphenol A (BPA) in endometrial cancer (EC) remains uncertain. In this study, we integrated toxicological prediction, network toxicology, gene expression profiling, survival analysis, and molecular ...

Abstract Economic inequality is a critical issue in elections and legislating, so having an informed electorate is vital to sensible policymaking. Unfortunately, misperceptions about the true extent of inequality abound....

Abstract Wild geese form large flocks, benefiting from shared vigilance against predators which increases feeding time. As spring progresses, males invest more in mate-guarding to protect paternity, so we hypothesised th...

Abstract Lichen planus (LP) is a chronic inflammatory disease of the skin and mucous membranes, marked by T cell infiltration and keratinocyte apoptosis. However, its immune microenvironment remains poorly understood. Us...