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Abstract Many sulfated polysaccharides (SPSs) possess useful physicochemical properties and biological activities and are widely used in industry. Currently, major SPSs are derived from livestock and marine organisms. To...

Abstract Leptospirosis is a worldwide zoonosis caused by pathogenic bacteria of the genus Leptospira. Lipopolysaccharide (LPS) is an immunodominant and protective antigen for Leptospira, but its biosynthesis remains poor...

Abstract Dietary fat absorption is among the most energy-demanding processes of nutrient uptake. Fatty acid activation, triglyceride synthesis, and the trafficking of chylomicrons through the secretory pathway - all requ...

Abstract Lilium brownii var. viridulum is rich in flavonoids, which offer antioxidant, anti-inflammatory, antitumor, and immunomodulatory effects. Recently, a novel, more resistant variant called L. brownii var. viridulu...

Abstract In response to concerns of environmental pollution caused by hazardous dyes, remediating these dyes is a challenge. Herein, we developed a genetic algorithm-artificial neural network (GA-ANN) based optimization ...

Abstract The activating signal co-integrator 1 complex subunit 3 (ASCC3), a multifunctional protein, has been implicated as a prognostic marker in several types of cancer. However, mechanisms underlying its prognostic va...

Abstract The growing prevalence of multidrug-resistant Gram-negative pathogens highlights the urgent need for therapeutic strategies that complement traditional antibiotics by targeting essential virulence pathways. Glyc...

Abstract Fungal inositol phosphorylceramide (IPC) synthase is an essential enzyme complex that catalyzes a critical step in sphingolipid biosynthesis. It is the molecular target of potent antifungal aureobasidin A (AbA)....

Abstract Perinatal failure in the growth hormone (GH)-insulin-like growth factor-1 (IGF-1) axis causes impaired body growth and central and autonomous neurodevelopmental disorders. However, whether a primary neurodevelop...

Abstract This study reports the green biosynthesis of bioactive selenium nanoparticles using Catharanthus roseus extract as a reducing and stabilizing agent. Liquid chromatography–electrospray ionization tandem mass sp...

Abstract Selenium (Se) enriched forest-grown ginseng is famous for its high Se content and excellent protein quality, which are necessary for varieties of metabolic processes and play an important role in both ginseng gr...