Buscar recursos académicos

Abstract Achieving both selectivity and cytotoxicity against cancer cells remains a major challenge in cancer therapy. Histone deacetylase (HDAC) inhibitors, such as tucidinostat, suppress tumor growth by epigenetically ...

Abstract Ovarian cancer (OC) ranks among the most aggressive malignancies of the female reproductive system. The immunosuppressive tumor microenvironment (TME) and pronounced spatial heterogeneity significantly restrict ...

Abstract B-cell translocation gene 3 (BTG3), a tumor suppressor, is reduced in expression in several malignancies, including ovarian cancer, colorectal cancer, and gastric cancer, but its role in oral squamous cell carci...

Abstract Publicly available, large-scale medical imaging datasets are crucial for developing and validating artificial intelligence (AI) models and conducting retrospective clinical research. However, multimodal datasets...

Abstract Prostate cancer (PCa) is one of the most common malignancies in men worldwide, yet early detection and accurate risk stratification remain challenging. MicroRNAs (miRNAs), key post-transcriptional regulators, ha...

Abstract Colorectal cancer (CRC) remains one of the most prevalent and lethal malignancies worldwide, with cancer stemness and metastasis being critical factors contributing to poor prognosis. While circular RNAs are eme...

Abstract Urological cancer (UC) is associated with significant adverse outcomes and poses a major global health burden. Although physical activity (PA) may reduce the risk of a single cancer site of UC through multiple p...