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Abstract Increased protein acetylation is frequently observed in the failing heart, including in hearts with heart failure with preserved ejection fraction (HFpEF). However, its role in the pathogenesis of HFpEF remains ...

Abstract The liver is a central organ controlling lipid and cholesterol metabolism and plays a key role in regulating lipoprotein profiles and cardiovascular disease risk. Males and females show clear differences in chol...

Abstract COVID-19, caused by SARS-CoV-2, is increasingly recognized as a systemic disorder with inflammation, endothelial dysfunction, and metabolic perturbations. This study aimed to characterize metabolic changes in CO...

Abstract Angiogenesis and its maturation play a crucial role in the progression and prognosis of head and neck squamous cell carcinoma (HNSCC). Tumor growth relies on an adequate blood supply to meet metabolic demands, w...

Abstract Minimal hepatic encephalopathy (MHE) is a cognitive, motor, and sleep-related disorder resulting from liver impairment, often linked to elevated ammonia levels. Zinc deficiency is common in patients with cirrhos...

Abstract “Miyamikhri,” a traditionally fermented bamboo shoot consumed by the Dimasa tribe of Assam, was investigated using a multi-omics approach integrating metagenomics, functional prediction, molecular docking, a...

Abstract The well-established tumor suppressor, Breast Cancer Susceptibility Gene 1 (BRCA1), has been implicated in lipid metabolism and in paradoxically promoting hepatocellular carcinoma (HCC); yet its mechanistic rol...