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MUSCLE: multiple sequence alignment with high accuracy and high throughput

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MUSCLE: multiple sequence alignment with high accuracy and high throughput

R. C. Edgar · Nucleic Acids Research · 2004

We describe MUSCLE, a new computer program for creating multiple alignments of protein sequences. Elements of the algorithm include fast distance estimation using kmer counting, progressive alignment using a new profile ...

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STRING v10: protein–protein interaction networks, integrated over the tree of life

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STRING v10: protein–protein interaction networks, integrated over the tree of life

Damian Szklarczyk; Andrea Franceschini; Stefan Wyder; Kristoffer Forslund; Davide Heller; Jaime Huerta‐Cepas; Milan Simonovic; Alexander Röth · Nucleic Acids Research · 2014

The many functional partnerships and interactions that occur between proteins are at the core of cellular processing and their systematic characterization helps to provide context in molecular systems biology. However, k...

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