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Abstract Background Results of ACTH stimulation test (ACTHst), pre‐ and post‐trilostane serum cortisol concentrations (SCCs), urine concentration (urine‐specific gravity [USG]), and urine cortisol : creatinine rati...

Abstract Background Crossmatching is used to prevent life‐threatening transfusion reactions in horses. Laboratory methods are laborious and technically challenging, which is impractical during emergencies. Hypothesis/O...

Abstract Background Serum folate is considered a biomarker of chronic enteropathy (CE) in dogs, but few studies have examined associations with markers of CE. Hypothesis/Objectives To evaluate serum folate concentrations...

Abstract Background Cardiac cachexia is common in people and dogs with congestive heart failure (CHF). However, the prevalence and effects of cardiac cachexia in cats are unknown. Objectives To determine the prevalence o...

Abstract Background Cardiac cachexia, loss of muscle mass associated with congestive heart failure (CHF), is associated with increased morbidity and shorter survival times in people, but an association between cardiac ca...

Abstract Background Stability of serum symmetric dimethylarginine (sSDMA) during short‐ and long‐term storage has not been assessed for the immunoassay of the Point‐of‐Care IDEXX Catalyst DX (POC) analyzer and th...

Abstract Background Acute Patient Physiologic and Laboratory Evaluation (APPLE) scores have not been reported in cats with diabetic ketoacidosis (DKA). Hypothesis In cats with DKA, APPLE scores will be significantly high...

Abstract Background Advanced machine learning methods combined with large sets of health screening data provide opportunities for diagnostic value in human and veterinary medicine. Hypothesis/Objectives To derive a model...

Abstract Background Laboratory results are influenced by presence and severity of disease, as well as preanalytical factors, analytical variation, and biological variation. Biological variation data for urinary protein: ...

ABSTRACT Background Many histological tests have been correlated with outcome in mast cell tumors (MCTs)in dogs, but their statistical independence is uncertain. Objective To investigate the clinical value of histologica...

Abstract Background Zonisamide (ZNS) is a newer generation antiseizure medication (ASM) used to treat epilepsy in dogs and cats. However, scientific and clinical information, particularly regarding monotherapy, is limite...

Abstract Background Nodal small cell B‐cell lymphoma subtypes in dogs cannot be distinguished by flow cytometry and information regarding treatment, prognosis, and outcome are limited. Hypothesis/Objectives Objectives ...

Abstract Background Gastric impactions (GI) have been identified as primary lesions (lone GI; LGI) or associated with other intestinal lesions (concurrent GI; CGI). Anecdotally, CGI resolve more rapidly with a better pr...

Abstract Background A panel of IgA‐based serologic assays might aid in the diagnosis of chronic enteropathy (CE) in dogs, a syndrome encompassing conditions such as food‐responsive enteropathy, immunosuppressant‐re...

Abstract Background Quantitative bacterial culture and susceptibility testing is the gold standard diagnostic for determining bacterial urinary tract infection. Transport of samples to external reference laboratories is ...

ABSTRACT Background Continuous renal replacement therapy (CRRT) is routinely used in human patients with acute kidney injury (AKI) but studies in dogs are scarce. Objective To describe CRRT in dogs and assess the utility...

ABSTRACT Background Immune‐mediated polyarthritis (IMPA) is a joint disease common in dogs. Although its prognosis is generally favorable, relapses are frequent, and predictive factors for relapse remain poorly charact...

Abstract Background Total serum calcium (tCa) concentrations are poorly predictive of ionized calcium (iCa) status in dogs. Hypothesis There is an optimal threshold of tCa concentration that is highly predictive of ioniz...

ABSTRACT Background Diagnosing epilepsy and dyskinesia in dogs relies on seizure semiology, laboratory workup, brain imaging, and electroencephalography. Variability in existing epilepsy surveys complicates comparison an...

Background Clinical signs of urinary tract disease in dogs often lead to prescription of antibiotics. Appropriate diagnostic work‐up could optimize treatment and reduce the risk of inappropriate use of antibiotics. Hyp...

ABSTRACT Background The glutaraldehyde test (GT) is used as a point‐of‐care test to detect inflammatory disease in cattle. Objectives Describe the relationship between GT and fibrinogen as well as GT and total protei...

Abstract Background Detection of free light chains (fLC) in animals relies on protein electrophoresis or the Bence‐Jones protein test on urine. Objective To describe the detection of both serum fLC (sfLC) and urine fLC...

ABSTRACT Background Many horses receive firocoxib over multiple years, and studies evaluating hematologic and biochemical values in these animals are lacking. Objective To describe the hematologic and biochemical values ...

Abstract Background Desoxycorticosterone pivalate (DOCP) is a commonly used mineralocorticoid replacement for dogs with primary hypoadrenocorticism (HA), but manufacturer‐recommended dosing protocols can be cost‐proh...