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Systemic curcumin administration mitigates neuropathic pain in a rat model of trigeminal neuralgia by suppressing TNF-α and pSTAT3 signaling

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Systemic curcumin administration mitigates neuropathic pain in a rat model of trigeminal neuralgia by suppressing TNF-α and pSTAT3 signaling

Dara Sari Arini et al · SAGE Publishing · 2026 · ISSN 1744-8069

Trigeminal neuralgia (TN) is a debilitating neuropathic facial pain disorder characterized by sudden, severe paroxysmal pain that markedly impairs quality of life. Although current pharmacological treatments provide pain...

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Effect of nonverbal behaviors and speech characteristics of online medical ECAs on patients’ satisfaction: The mediating roles of empathy and trust

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Acceso abierto Artículo DOAJ

Effect of nonverbal behaviors and speech characteristics of online medical ECAs on patients’ satisfaction: The mediating roles of empathy and trust

Fei Fang et al · SAGE Publishing · 2026 · ISSN 2055-2076

Objective Embodied conversational agents (ECAs) play a crucial role in digital healthcare. While existing studies have examined the effect of ECAs’ appearances and nonverbal behaviors on acceptance, the mechanism by wh...

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