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Hereditary Hearing Loss (HHL) is a common trait affecting 1 in 2000 new born children. The presence of over 100 different genes involved in HHL, lead us to go on board with Whole Exome Sequencing (WES) in order to search...

Abstract Background ATF3 was found to play a complex role in various cancers; however, its systematic function in kidney renal clear cell carcinoma (KIRC) and across pan-cancer contexts remained incompletely understood. ...

Abstract Background Hepatocellular carcinoma (HCC) is a critical condition characterized by unchecked cellular growth in the liver, often leading to systemic inflammation and organ failure. Although its complex molecular...

Abstract In this study, we reported the synthesis and characterization of a novel magnetic polystyrene nanocatalyst functionalized with L-glutamine (L-Glu-MPS) and evaluation of its catalytic performance in a multicompon...

Abstract A first-principles study of the structural, electronic, magnetic, mechanical, and optical properties of the double perovskite Ca₂GaAsO₆ is presented using density functional theory with the Perdew-Burke-Ernz...

Abstract Eleusine coracana (L.) Gaertn., commonly known as Ragi or finger millet, is a nutrient-rich cereal traditionally valued for its health-promoting properties. However, its precise molecular mechanisms and therapeu...

Abstract JMJD6, a bifunctional epigenetic modulator within the Jumonji C family, has garnered increasing attention for its potential roles in tumorigenesis, yet its pan-cancer prognostic and mechanistic significance rema...

Abstract Carbon nanotubes (CNTs) are promising nanomaterials with applications in biomedicine, including drug delivery and biosensing, due to their stability, biocompatibility, and ease of surface modification. However, ...

Abstract This study, drawing on the Multidimensional Model of Work Orientations, investigates the relationship between personal values, the meanings attributed to work (work orientations), and job satisfaction in a sampl...

Abstract Spatial variations in stiffness and mass density make the free-vibration behavior of tridirectionally functionally graded material (3D-FGM) beams highly sensitive to material gradation, while computationally eff...

Abstract Colostrum is the first mammary secretion produced after parturition and represents a biologically active fluid essential for neonatal survival, immune maturation, and early growth. Despite its importance, breed-...

Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy in which immune dysregulation and metabolic remodeling are common features. Laminin subunit alpha 3 (LAMA3), a component of lamini...