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Evaluation of the predictive and prognostic potential of blood immune cell profiles in metastatic cancer patients treated with immune checkpoint inhibitors
Artículo
Acceso abierto Artículo DOAJ
Evaluation of the predictive and prognostic potential of blood immune cell profiles in metastatic cancer patients treated with immune checkpoint inhibitors
Veera Nurmela et al · Springer · 2026 · ISSN 1432-0851
Abstract Immune checkpoint inhibitors (ICI) have transformed the treatment of metastatic malignancies, yet only 20–40% of unselected patients benefit. Peripheral blood could offer a minimally invasive and dynamic sourc...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Acetylcholinesterase inhibitory activity of a naturally occurring peptide isolated from Boana pulchella (Anura: Hylidae) and its analogs
Artículo
Acceso abierto Artículo CONICET Digital
Acetylcholinesterase inhibitory activity of a naturally occurring peptide isolated from Boana pulchella (Anura: Hylidae) and its analogs
Sanchis, Ivan et al · Springer · 2020 · ISSN 0939-4451
Alzheimer’s disease (AD), the most common form of dementia, is a growing problem worldwide, with 10 million incident cases registered every year. The complex etiology of AD has not been clarified yet and represents an ...
Idioma eng
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Application of plant residues in combination with nitrogen fertilizer to improve soil N availability, enhance nitrogen utilization efficiency (NUE) and grain productivity in tropical rice paddies
Artículo
Acceso abierto Artículo DOAJ
Application of plant residues in combination with nitrogen fertilizer to improve soil N availability, enhance nitrogen utilization efficiency (NUE) and grain productivity in tropical rice paddies
Jasmin Sultana et al · Springer · 2026 · ISSN 3005-1223
Abstract In agricultural environments, nitrification inhibitors (NIs), both synthetic and biological, are widely used to reduce nitrogen (N) losses through various mechanisms. Two plant residues were selected to evaluate...
LCC TENDOkdlb2xvZ3k~; TENDOkVudmlyb25tZW50YWwgc2NpZW5jZXM~Idioma eng
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Comprehensive study of garlic peel extract coating against mild steel corrosion in saline medium
Artículo
Acceso abierto Artículo DOAJ
Comprehensive study of garlic peel extract coating against mild steel corrosion in saline medium
Bindu Mangla et al · Springer · 2026 · ISSN 2730-7700
Abstract Natural materials (NMs) have emerged as better alternatives for the mitigation of corrosion of metals. NMs can be used as both inhibitors and coatings; however, they have been used mostly as inhibitors. In this ...
LCC LCC:Chemical engineeringIdioma eng
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First-line PD-1 inhibitor plus chemotherapy improves outcomes in advanced gastric cancer and correlates with specific biomarkers in a real-world cohort
Artículo
Material complementario disponible Artículo DOAJ
First-line PD-1 inhibitor plus chemotherapy improves outcomes in advanced gastric cancer and correlates with specific biomarkers in a real-world cohort
Xiaoting Ma et al · Springer · 2026 · ISSN 2730-6011
Abstract Background Immune checkpoint inhibitors (ICIs) have become the main treatment method for human epidermal growth factor receptor 2 (HER2)-negative advanced gastric cancer (GC). This study analyzed from real-world...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Immune classification of advanced melanoma identifies non-responders to anti-PD1 therapy
Artículo
Acceso abierto Artículo DOAJ
Immune classification of advanced melanoma identifies non-responders to anti-PD1 therapy
Angelo Gámez-Pozo et al · Springer · 2026 · ISSN 1432-0851
Abstract Background Immunotherapy based on anti-PD1 inhibitors has significantly improved survival in advanced melanoma. However, a significant proportion of patients do not benefit, and predicting response to immunother...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Inhibition of Survival Pathways MAPK and NF-kB Triggers Apoptosis in Pancreatic Ductal Adenocarcinoma Cells via Suppression of Autophagy
Artículo
Acceso abierto Artículo CONICET Digital
Inhibition of Survival Pathways MAPK and NF-kB Triggers Apoptosis in Pancreatic Ductal Adenocarcinoma Cells via Suppression of Autophagy
Papademetrio, Daniela Laura et al · Springer · 2016 · ISSN 1776-2596
Background: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease with a survival rate of 4–6 months from diagnosis. PDAC is the fourth leading cause of cancer-related death in the Western world, with a mort...
Idioma eng
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