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Lupus erythematosus is an autoimmune disease characterized by complex immune disturbances concerning humoral and cell-mediated immune responses. Despite intensive research, many pathological processes regarding this diso...

Antimalarial drugs used in medicine for over 300 years, nowadays, due to their anti-inflammatory, immunomodulatory and antiproliferative photoprotective properties, are used in the therapy of many dermatologic and rheuma...

Introduction . Bed bugs belong to the family Cimicidae, which includes two cosmopolitan species: Cimex lectularius and Cimex hemipterus. Bed bugs feed on the blood of humans and animals. As a result of bites, skin change...

Introduction . Cutaneous leiomyomas are rare, benign smooth muscle neoplasms of the skin. According to the origin of the tumor, there are three types of cutaneous leiomyomas: piloleiomyomas, angioleiomyomas and genital l...

Introduction. Autoimmune polyglandular syndrome type 1 (APS-1) is a type of polyendocrinopathy, inherited in an autosomal recessive manner. Beside the classic triad of symptoms (candidiasis of the skin and mucous membr...

Diabetes is a chronic systemic disease affecting 8.3% of the general population, thus constituting an important clinical and financial problem for healthcare systems throughout the world. Complications of diabetes damage...

Introduction . Pitted keratolysis (PK) is a mild infectious skin disorder caused by Corynebacterium spp., Kytococcus sedentarius or Dermatophilus congolensis . These bacteria produce enzymes that digest keratin, cau...

Introduction . Progressive macular hypomelanosis (PMH) is a cutaneous pigmentary disorder resulting from a deficit of melanin and manifesting with disseminated hypopigmented macules. Pityriasis alba, post-inflammatory hy...

Hand eczema is a common skin disorder with significant functional and economic impacts. Conventional therapy options, such as topical corticosteroids, calcineurin inhibitors, phototherapy and systemic immunosuppressants,...

Atopic dermatitis is a frequent, chronic and recurrent inflammatory skin disease with complex etiology. Typical symptoms of this disease are persistent itching and dry skin. To assess the severity of the disease we use v...

Introduction . Dermatomyositis is a rare systemic disease of connective tissue characterized by inflammation of the muscles and the skin. Malignant melanoma is a cancer that begins in melanocytes in the skin, mucosa of t...

The large surface area of the skin, high metabolism and location at the border of two environments (external and internal) cause continuous production of free radicals within the skin. There are two mechanisms of skin ph...

Introduction. Psoriasis rupioides is a rare type of psoriasis. Although a description of it is easy to find in most textbooks of psoriasis, it does not have a place in the ICD-10 classification, and there have been ver...

Introduction. Ramsay Hunt syndrome is a rare disease characterized by complications of herpes zoster oticus. This syndrome is defined by characteristic skin lesions with paresis of the facial and/or vestibulocochlear n...

Introduction. Rowell’s syndrome is a rare subtype of subacute lupus erythematosus associated with erythema multiforme-like skin lesions, positive antinuclear antibodies and anti-Ro/La-antibodies. Objective . To pr...

Skin tags are classified as benign lesions. They occur mainly on the skin of the neck, eyelids, armpits, and groin as pedicles and soft nodules. Their occurrence is associated with obesity, insulin resistance, atherogeni...

Vitiligo is a quite frequently occurring skin disease. Although it does not cause any pain or internal organ damage, it constitutes a significant cosmetic problem having a significant impact on quality of life. A number ...