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120 resultados encontrados.

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Deep Brain Stimulation Induces Antidepressant Effects by Restoring High‐Fidelity Communication in the BNST‐NAc Circuit
Artículo
Acceso abierto Artículo DOAJ
Xin Lv et al · Wiley · 2026 · ISSN 2198-3844
ABSTRACT Deep brain stimulation (DBS) for treatment‐resistant depression (TRD) is challenged by significant individual variability in efficacy and unclear neural circuit mechanisms. To address this, a cross‐species, ...
LCC TENDOlNjaWVuY2U~Idioma eng
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Open Access
Development of Ambient-Cured Geopolymer Concrete: Investigating Bottom Ash as a Sustainable Alternative to Natural River Sand
Artículo
Acceso abierto Artículo DOAJ
Lemma Beressa Gudeta et al · Wiley · 2026 · ISSN 1687-8442
Portland cement production is a major contributor to global CO2 emissions, and the scarcity of natural river sand limits conventional concrete production. Despite increasing interest in geopolymer concrete (GPC), studies...
LCC LCC:Materials of engineering and construction. Mechanics of materialsIdioma eng
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Open Access
Deciphering the Impact of RAC1‐SPTAN1 in ARPKD Cystogenesis Using Multifaceted Models
Artículo
Acceso abierto Artículo DOAJ
Shohei Kuraoka et al · Wiley · 2026 · ISSN 2198-3844
ABSTRACT Autosomal recessive polycystic kidney disease (ARPKD) leads to severe renal cysts and progressive kidney dysfunction, with no approved treatments. The absence of such cystic phenotypes in Pkhd1−/− mice under...
LCC TENDOlNjaWVuY2U~Idioma eng
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Open Access
Development and Structural Characterization of UTE‐156, a Covalent Inhibitor of the VCP/p97 AAA+ ATPase
Artículo
Acceso abierto Artículo DOAJ
Daniela Tamayo‐Jaramillo et al · Wiley · 2026 · ISSN 2198-3844
ABSTRACT The AAA+ ATPase valosin‐containing protein (VCP/p97) is a central regulator of protein homeostasis that is well characterized for its role in extracting and remodeling ubiquitinated substrates. Dysregulation o...
LCC TENDOlNjaWVuY2U~Idioma eng
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Open Access
Effect of Plyometric Training on Vertical Jump Height in Pre‐Peak Height Velocity Boys and Girls Aged 9–11 Years
Artículo
Acceso abierto Artículo DOAJ
Lee D. McGarrigal et al · Wiley · 2026 · ISSN 1746-1391
ABSTRACT This study aimed to compare changes in countermovement jump (CMJ) height and take‐off velocity, force and power in pre‐peak height velocity (pre‐PHV) boys and girls aged 9–11 years following 6 weeks of ...
LCC TENDOlNwb3J0cw~~Idioma eng
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Open Access
Activated Platelet–Released Heat Shock Protein 90α Triggers Autophagy‐Dependent Neutrophil Extracellular Trap Formation and Amplifies Sepsis
Artículo
Acceso abierto Artículo DOAJ
Chengbo Wang et al · Wiley · 2026 · ISSN 2198-3844
ABSTRACT Platelets are crucial to the development of thrombosis and coagulation abnormalities in sepsis, but the mechanisms by which they contribute to these pathological processes are not fully understood. Here, we iden...
LCC TENDOlNjaWVuY2U~Idioma eng
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Are Dry‐Land Force–Velocity Abilities Related to In‐Water Load–Velocity Profiles in Sprint Swimming?
Artículo
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Yannis Raineteau et al · Wiley · 2026 · ISSN 1746-1391
ABSTRACT Swimming propulsion can be improved using dry‐land resistance training. Indeed, previous studies showed that the ability to produce maximal power and maximal force on dry‐land is strongly related to sprint s...
LCC TENDOlNwb3J0cw~~Idioma eng
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Aspimultiols B and C, Two New Steroids From the Leaves and Rhizomes of Aspidistra multiflora
Artículo
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Diep-Xuan-Ky Nguyen et al · Wiley · 2026 · ISSN 2090-9071
Two new polyhydroxylated steroids, including one spirostane-type (1) and one pregnane-type (2) skeleton, together with three known analogs, (25R)-spirost-5-en-3β-ol (3), (25S)-5β-spirostane-3β-ol (4), and (25R)-spiros...
LCC TENDOkNoZW1pc3RyeQ~~Idioma eng
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Open Access
CO2 Electroreduction on Silver and Silver-Based Cathodes in Aqueous and Nonaqueous Solutions: A Review
Artículo
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Оrest Kuntyi et al · Wiley · 2026 · ISSN 2090-9071
The scientific literature on the electrochemical conversion of CO2 on silver and silver-based cathodes in aqueous solutions and nonaqueous media has been analyzed. It has been shown that the most problematic issues regar...
LCC TENDOkNoZW1pc3RyeQ~~Idioma eng
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Open Access
Co-Occurrence of Resistance to Aminoglycosides and Carbapenems in Klebsiella pneumoniae: A Critical Threat to Public Health
Artículo
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Rafael Artur de Queiroz Cavalcanti de Sa et al · Wiley · 2026 · ISSN 1687-9198
Antimicrobial resistance (AMR) in Klebsiella pneumoniae, especially the co-occurrence of resistance to aminoglycosides and carbapenems, represents a serious threat to global public health. This study reviews the prevalen...
LCC TENDOk1pY3JvYmlvbG9neQ~~Idioma eng
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Open Access
Coacervate‐Mediated Lysosome‐Targeting Antibody Delivery for Protein Degradation
Artículo
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Dingdong Yuan et al · Wiley · 2026 · ISSN 2198-3844
ABSTRACT Selective recognition of cancer‐associated proteins (CAPs) by antibodies, followed by their delivery into the intracellular organelle, the lysosome, results in targeted degradation of CAPs and suppresses the g...
LCC TENDOlNjaWVuY2U~Idioma eng
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Open Access
Color-Contrast Adjustment With a 3D Head-Up System to Aid Capsulorhexis After ICG Staining: Single-Patient Case Report From a Tertiary Center
Artículo
Material complementario disponible Artículo DOAJ
Yukihisa Takada et al · Wiley · 2026 · ISSN 2090-6730
We report a single case in which continuous curvilinear capsulorhexis (CCC) was safely completed using NGENUITY in 3D head-up surgery (HUS) during cataract surgery. Visibility of the dye-stained anterior capsule was impr...
LCC TENDOk9waHRoYWxtb2xvZ3k~Idioma eng
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Construct Validity and Reliability of a Virtual Reality Cricket Batting Simulator
Artículo
Acceso abierto Artículo DOAJ
Oliver R. Runswick et al · Wiley · 2026 · ISSN 1746-1391
ABSTRACT Virtual reality technologies offer sports performance organisations new possibilities for measuring and enhancing performance. This is particularly the case in cricket where training is significantly constrained...
LCC TENDOlNwb3J0cw~~Idioma eng
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Open Access
Continuation-Enhanced Harmonic Balance Method for Nonlinear Dynamics in Rotating Machinery
Artículo
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Muhammad Umar et al · Wiley · 2026 · ISSN 1875-9203
Nonlinear response conception in rotating machinery, particularly in systems with squeeze film dampers (SFDs), pose significant challenges for established time-domain numerical methods due to bifurcations and critical po...
LCC TENDOlBoeXNpY3M~Idioma eng
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Effects of L‐Tyrosine Ingestion on Endurance Performance in Mentally Fatigued Cyclists
Artículo
Material complementario disponible Artículo DOAJ
Luiz José Frota Solon‐Júnior et al · Wiley · 2026 · ISSN 1746-1391
ABSTRACT This study investigated whether L‐tyrosine supplementation enhances endurance performance in mentally fatigued cyclists. Twelve recreational cyclists completed two constant‐workload tests to exhaustion cycli...
LCC TENDOlNwb3J0cw~~Idioma eng
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Material complementario
Experimenting With a Digital Application to Codesign Ikat Textile Patterns With Weaving Community
Artículo
Acceso abierto Artículo DOAJ
Warin Boonyaputthipong et al · Wiley · 2026 · ISSN 2578-1863
This article presents a multidisciplinary research project that involves a digital application developed for ikat weaving communities from Chonnabot District in Khon Kaen Province in Thailand. The app is aimed at generat...
LCC TENDOlBzeWNob2xvZ3k~; TENDOkluZm9ybWF0aW9uIHRlY2hub2xvZ3k~Idioma eng
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Open Access
Feasibility and Potential Effects of Exercise Training Combining Eccentric and Concentric Cycling in Patients With Breast Cancer
Artículo
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Elyse Hucteau et al · Wiley · 2026 · ISSN 1746-1391
ABSTRACT Breast cancer treatment impairs aerobic and neuromuscular capacities, leading to a decrease in quality of life. Exercise may counteract these effects if it is individualized to patient characteristics. This stud...
LCC TENDOlNwb3J0cw~~Idioma eng
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Ga Doping Enables Precision Alloy‐to‐Wire Regulation: Synergistic Enhancement of the Mechanical Properties of CuSn Alloy and the Superconducting Properties of Nb3Sn
Artículo
Material complementario disponible Artículo DOAJ
Dazhuo Song et al · Wiley · 2026 · ISSN 2198-3844
ABSTRACT Cu–Sn alloy is a key raw material used in the preparation of Nb3Sn superconducting wires using the bronze method. The mechanical properties of this Cu–Sn alloy are directly responsible for determining the pr...
LCC TENDOlNjaWVuY2U~Idioma eng
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Immune Checkpoint Inhibitors and Immunomodulators for Cancer Immunotherapy: Insights Into Resistance and Therapeutic Strategies
Artículo
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Fangquan Chen et al · Wiley · 2026 · ISSN 2198-3844
Abstract Cancer immunotherapy has redefined cancer treatment. However, the molecular and cellular basis of immune evasion and therapeutic resistance remains incompletely understood. Early immune checkpoint inhibitors hav...
LCC TENDOlNjaWVuY2U~Idioma eng
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Open Access
In Vivo Evaluation of a Novel Long-Term Intravascular Implantable Continuous Blood Glucose Monitor in an Ovine Model: A Glucotrack Inc. Investigation
Artículo
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Mark A. Tapsak et al · Wiley · 2026 · ISSN 2314-6753
Implantable intravascular continuous blood glucose monitors (CBGMs) offer a promising approach for accurately measuring glucose levels with short lag times and improved reliability when compared with conventional laborat...
LCC LCC:Diseases of the endocrine glands. Clinical endocrinologyIdioma eng
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Living Hydrogels: Harnessing Microorganism–Material Synergy for Next‐Generation Therapeutics
Artículo
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Shuifang Mao et al · Wiley · 2026 · ISSN 2198-3844
ABSTRACT Microorganism‐based therapies, particularly those utilizing probiotics, have emerged as a powerful biomedical strategy owing to their inherent living functionalities. These living systems can dynamically inter...
LCC TENDOlNjaWVuY2U~Idioma eng
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Open Access
Modern Advances in Velvet Antler Research: From Identification Methods to Pharmacological Mechanisms
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Maodie Zhang et al · Wiley · 2026 · ISSN 2314-5765
Velvet antler, a valued traditional medicine of animal origin, contains an abundance of bioactive compounds including amino acids, peptides, proteins, and nucleosides. It exhibits notable health-promoting properties such...
LCC LCC:Nutrition. Foods and food supply; TENDOkZvb2QgcHJvY2Vzc2luZyBhbmQgbWFudWZhY3R1cmU~Idioma eng
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