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La aspirina (ácido acetilsalicílico) es uno de los medicamentos más viejos y difundidos del mundo. Son múltiples sus beneficios, pero recién en los últimos años se han comenzado a desentrañar los mecanismos molec...

BACKGROUND: Antiplatelet agents are the mainstay for secondary prevention of non-cardioembolic stroke. This systematic review examined the safety and efficacy of short-, middle-, and long-term aspirin in combination with...

Estudia el efecto de la aspirina en la enfermedad de Chagas.

Materias / palabras clave: Ácido acetilsalicílico.; Experimentos.; Química orgánica.; Aspirin.; Acido acetilsalicilico; Quimica organica

This research paper tackles a developed method for Aspirin and Pyridoxine drugs determination in their pure forms and pharmaceutical formulations. It is based on the formation of nucleophilic substitution reaction betwee...

Eight new copper(II) complexes with halo-aspirinate anions have been synthesized: [Cu 2(Fasp) 4(MeCN) 2]·2MeCN (1), [Cu 2(Clasp) 4(MeCN) 2]·2MeCN (2), [Cu 2(Brasp) 4 (MeCN) 2]·2MeCN (3), {[Cu 2(Fasp) 4(Pyrz)]·2MeCN} ...

Background: Anaemia remains a major public health concern in pregnancy and is associated with adverse maternal and perinatal outcomes. Low-dose aspirin (LDA) is widely prescribed to reduce the risk of preeclampsia (PE),...

Abstract Objective Preeclampsia is a major cause of perinatal and maternal morbidity and mortality. Our objective is to assess the performance of a combined screening test for preeclampsia in the first trimester and th...

D-002, a mixture of six beeswax alcohols, with gastroprotective and anti-inflammatory effects, was compared with naproxen, aspirin and their combined therapy in rats with cotton pellet granuloma. After pellet implantatio...

Materias / palabras clave: Aspirin; Mechanism (biology); Mechanism of action; Prostaglandin; Pharmacology; Chemistry; Action (physics); Medicine; Biochemistry; Physics; In vitro; Quantum mechanics

ObjectiveThis review summarizes the current evidence on the impact of isolated antiphospholipid antibody positivity (IAAP) on pregnancy outcomes. It analyzes risk differentials across antibody subtypes, synthesizes the u...

Background: Guidelines do not recommend routine glycoprotein IIb/IIIa inhibitors (GPIs), reserving them for high thrombotic-risk or bailout cases. Most acute coronary syndrome (ACS) patients undergoing percutaneous coron...

The U.S. Department of Labor reported that working adults with at least a four-year college degree earned an annual average salary of $63,400 compared to the $24,300 salary of high school graduates with no college. The p...

Abstract Background Pre-eclampsia is a multisystem disorder affecting 2.8% of pregnancies in the UK. It usually presents after 20-week gestation with new-onset high blood pressure and proteinuria. Complications include e...

Hip fractures in the elderly represent a significant cause of morbidity and mortality. A considerable proportion of these patients are on antiplatelet medications, such as aspirin (Ecospirin) and clopidogrel (Clopitab), ...

Abstract Background Children with congenital and acquired heart disease (CAHD) are at high risk for venous thromboembolism (VTE). Traditional anticoagulants such as vitamin K antagonists (VKAs) and low-molecular-weight h...

Polycythemia is a myeloproliferative neoplasm characterized by uncontrolled proliferation of red blood cells due to mutations in early hematopoietic cells, often linked to Janus kinase 2 (JAK2) gene mutations. Polycythem...

BackgroundTo compare the prognostic effects of different single antiplatelet therapy (SAPT) regimens (aspirin vs. clopidogrel) in patients with acute coronary syndrome (ACS) at high-risk for ischemia and bleeding followi...

Abstract Objective To assess maternal and perinatal outcomes of pregnancies in women with chronic hypertension (CH). Methods Retrospective cohort of women with CH followed at a referral center for a 5 year period (2012-...

Preeclampsia represents an unmasking of underlying vascular and metabolic vulnerability during the physiologic stress of pregnancy. Current first-trimester screening relies heavily on body mass index which incompletely c...

Abstract Background Characterization of the clinical signs, response to treatment and prognosis can be useful information for decision‐making when evaluating cattle with pharyngeal trauma. Objective To describe the sig...

Oxidative stress (OS), derived from an imbalance between reactive oxygen species (ROS) accumulation and impaired antioxidant defense, is a recognized cause of atherothrombosis, through a complex interaction between low-g...

This study investigated the structural barriers and motivational drivers in the adoption of edible mushroom cultivation in Yaoundé, Cameroon. The study involved 105 beneficiaries of the National Mushroom Project, compri...