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Fibrosis, increased amounts of immune cells and expression of COX-2 in the testes of infertility patients provide circumstantial evidence for a specific testicular milieu, in which reactive oxygen species (ROS) could be ...

ABSTRACT Amphibians are excellent bioindicators because they are sensitive to chemical pollution and can indicate ecosystem changes due to the presence of or exposure to chemical compounds. Here we report evidence of the...

Evidence of teratogenesis and mutagenesis documented in the palynological assemblages of the Middle Triassic Quebrada de los Fósiles Formation, San Rafael Depocenter (Mendoza, Argentina) provide an independent testimony...

ABSTRACT Background and Aims Evidence‐based practice (EBP) is central to high‐quality acute care, yet evidence on how specialist nurses engage with EBP remains limited. This study aimed to examine EBP beliefs, organi...

Research has highlighted that no instrument with adequate evidence of validity and reliability currently exists to assess quality of life (QoL) in children with Down syndrome (DS). Important limitations have been pointed...

Materias / palabras clave: Derecho.; Derecho penal.; Criminal procedure.; Civil rights.; Evidence, Criminal.; Admissible evidence; Spain.; Exclusionary rule (Evidence); España.; Prueba ilícita; Proceso penal

Materias / palabras clave: Evidence (Law); Criminal procedure.; Prueba (Derecho); Procedimiento penal.

Materias / palabras clave: methods, evidence synthesis, evidence based medicine, evidence based healthcare, medical statistics; Medicine: Public aspects of medicine | Medicine: Medicine (General): Computer applications to medicine. Medical informa...

Materias / palabras clave: evidence-based medicine, medicine, critical thinking, evidence gaps, evidence-based practice, healthcare; Medicine: Medicine (General)

ObjectiveTo assess the quality of the literature related to the carcinogenicity of perfluorooctane sulfonic acid （PFOS） using the weight of evidence method， and to evaluate its carcinogenic risk through the dose-re...

Abstract Background Research has produced a substantial and expanding body of evidence-based practices (EBPs), encompassing interventions, programmes, clinical guidelines, protocols, care pathways and models of care supp...

Regulatory science governing monoclonal antibody development has undergone a profound transformation over the past decade, shifting from empiricism-driven paradigms toward evidence-efficient, mechanism-based frameworks g...

Abstract This is the protocol for a Campbell systematic review. The objectives are as follows: Our aim is to collect, assess, and synthesise all the available empirical evidence on what works to support evidence‐inform...

ObjectiveTo summarize the best evidence for non-surgical intervention in periodontitis among patients with type 2 diabetes mellitus, and to provide a basis for medical and nursing staff to carry out periodontitis managem...

Abstract In this paper we present an analysis of the role of randomized controlled trials (RCTs) in the regulation of health claims (claims about additional health benefits provided by foods). Currently there is a line o...

Materias / palabras clave: clinical decision making; evidence based practice; evidence based treatment; intervention planning; treatment planning

In the face of socioeconomic challenges, this paper develops and empirically demonstrates the Gondauri Index (GI) as a reproducible, diagnostics-first composite framework for benchmarking macro-financial resilience acros...

ObjectiveChronic pain, a major global public health burden, is primarily driven by altered central pain processing, which conventional treatments rarely target directly. This systematic review and meta-analysis synthesiz...

The increasing use of real-world evidence (RWE) and real-world data (RWD) to assess post-market medical devices (MDs) might satisfy the urgent need for data sharing and traceability. This study sought to (i) get an overv...

Abstract Background Sarcopenia, the age-related loss of muscle mass and strength, is a leading cause of disability and frailty in older adults. Though primarily seen as a musculoskeletal condition, emerging evidence sugg...

Abstract Background Sub-Saharan Africa (SSA) has been witnessing a persistent increase in the burden of cardiovascular diseases (CVD), such as stroke and heart disease, over several decades. A key driver of this burden h...

Background: Ankle fractures are common injuries that often present first to general practitioners, urgent care clinicians, or emergency medical services (EMS) teams. Inadequate prehospital management such as suboptimal s...

AbstractThe digital mental health (DMH) industry has grown drastically over the last decade; yet, many DMH products have failed to demonstrate meaningful clinical outcomes, in large part due to lack of scientific evidenc...