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A simple procedure was described for the determination of Withanolide A and Withanolide B in Ashwagandha root by HPLC. Separation was achieved on a Spherisorb C18 column with Water: Acetonitrile in the gradient elution. ...

In the present study, a high performance liquid chromatographic method was developed and validated for determination of chromatographic purity and stress stability of the anti-retroviral drug lamivudine. The different an...

Diabetes mellitus (DM) is a serious health problem affecting millions of individuals worldwide. It is showed that some changes of many enzymes and transporters concerned with metabolism and disposal of drug have taken ...

A new HPLC-DAD method has been developed and validated for the simultaneous analysis of nine flavonoids (rutin, myricetin, quercitrin, quercetin, luteolin, genistein, kaempferol, apigenin, and isorhamnetin) in Ginkgo bil...

Current quality control patterns are limited to industrial application, for most the natural chemical reference substances are expensive and unavailable. Here in, quantitative analysis of multi-components with single mar...

A simple, sensitive and reproducible RP-HPLC method was developed and validated for the simultaneous determination of atorvastatin and gemfibrozil in human plasma. After a single step liquidliquid extraction of both the ...

The present study was designed to explore the total phenols and flavonoids content in leaf fractions of Plantago australis L., and their radical scavenging activity by 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. The free...

Este trabalho objetivou caracterizar e avaliar a qualidade de matérias-primas (MPs) de primaquina de diferentes fornecedores, designadas amostras A, B, C e D. Os resultados de características físicas, solubilidade, fa...

Oral administration to rats of Rhizoma Paridis saponins (RPS) from Paris polyphylla var. yunnanensis extracts have been found to show strong anti-tumor activity, but the effective constituents were not known. To detail...

Um método de cromatografia líquida de alta eficiência mais econômico devido ao uso de um padrão secundário de ampicilina tri-hidratada foi validado e utilizado para a quantificação de ampicilina sódica injetáve...

New fast liquid chromatographic and capillary zone electrophoresis methods were developed and validated for simultaneous determination of atenolol and chlortalidone in combined dose tablets. The reversed phase HPLC metho...

New rapid first-derivative spectrophotometric (UVDS) and a stability-indicating high performance liquid chromatographic (HPLC) methods were developed, validated and successfully applied in the analysis of loratadine (LT)...

The purpose of this study was to obtain information on the photochemical properties of ketoconazole, an antifungal agent. Photodegradation of ketoconazole in solution and shampoo under exposure to UV-C (254 nm) and UV-A ...