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Abstract Restriction of fetal substrate supply has an adverse effect on surfactant maturation in the lung and thus affects the transition from in utero placental oxygenation to pulmonary ventilation ex utero. However, th...

BackgroundGranulomatous-lymphocytic interstitial lung disease (GLILD) is a major cause of morbidity and mortality in common variable immunodeficiency (CVID), yet its pathophysiology remains incompletely understood, and n...

Abstract Background Consumer advocacies emphasize embedding lived experience into palliative care provision. However, tokenistic consumer involvement often hinder meaningful consumer participation in decision-making proc...

The rapid annual increase in conditions classified as inborn errors of immunity (IEI), along with associated genetic variants, creates diagnostic challenges. The comprehensive nature of exome sequencing (ES) and genome s...

Lassa fever is a zoonotic disease endemic to several West African countries, with seasonal outbreaks and potential to cause future epidemics. Vaccines and other medical countermeasures are in development, requiring relia...

Abstract Transcriptional master regulators drive cell fate transitions. Peroxisome proliferator-activated receptor γ (PPARγ) is the master regulator of adipogenesis, and its expression must therefore be tightly regulat...

Abstract Background High rates of chronic kidney disease (CKD) are well recognised in Australia’s Indigenous people, but kidney replacement therapy (KRT) registrations give an incomplete view of disease burden and outc...

ABSTRACT Background and Aims Hearing and vision impairments are prevalent health conditions among older adults, negatively affecting functional ability, mental and social well‐being, quality of life and increasing the ...

IntroductionChild malnutrition remains a public health and development challenge, particularly in Africa. Dairy can play a significant role in improving child nutrition and can plausibly be incorporated into Africa’s s...

Abstract Background Spaceflight introduces unique environmental stresses that challenge plant growth and development, necessitating an understanding of molecular responses to enable sustainable agriculture for long-durat...

Exercise promotes neurogenesis and enhances memory consolidation while reducing the retention of aversive memories and anxiety-like behaviors. While our previous work found that acute exercise alters neurotransmitter con...

Abstract Clear cell renal cell carcinoma (ccRCC) represents the most common form of kidney cancer and is typified by biallelic inactivation of the von Hippel-Lindau (VHL) tumour suppressor gene. Here, we undertake genome...