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43 resultados encontrados.

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Artificial intelligence assisted multi-model pathological diagnosis of breast cancer based on multispectral autofluorescence images
Artículo
Acceso abierto Artículo DOAJ
Jiahong Sun et al · Nature Portfolio · 2026 · ISSN 2374-4677
Abstract Virtual staining technology offers a promising solution to overcome the time-consuming and sample-consumption nature of conventional histochemical staining in breast cancer pathology. This study presents a novel...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Open Access
Cardiac myxoma: Clinical and pathological features of a rare benign primary heart neoplasm among Tuzla Canton patients
Artículo
Material complementario disponible Artículo DOAJ
Salkić Jasna et al · Sciendo · 2026 · ISSN 2668-7763
Objective: To investigate the clinical and pathological features of a rare benign primary cardiac tumour.
LCC LCC:MedicineIdioma eng
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Comparison of changes in dynamic contrast-enhanced magnetic resonance imaging and flourine-18 fluorodeoxyglucose positron emission tomography/computed tomography parameters from baseline to post-neoadjuvant therapy in predicting pathological response in breast cancer
Artículo
Material complementario disponible Artículo DOAJ
Hüseyin Akkaya et al · Turkish Society of Radiology · 2026 · ISSN 1305-3825
PURPOSE: This study aimed to compare the value of differences (∆) in parameters obtained via both dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) and flourine-18 fluorodeoxyglucose positron emission to...
LCC TENDOk1lZGljYWwgcGh5c2ljcy4gTWVkaWNhbCByYWRpb2xvZ3kuIE51Y2xlYXIgbWVkaWNpbmU~Idioma eng
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Genomic alterations and dynamic molecular residual disease monitoring predict pathological response to neoadjuvant chemoimmunotherapy in esophageal squamous cell carcinoma
Artículo
Acceso abierto Artículo DOAJ
Dijian Shen et al · Frontiers Media S.A · 2026 · ISSN 1664-3224
BackgroundApproximately 40-60% of patients with locally advanced esophageal squamous cell carcinoma (ESCC) exhibit suboptimal responses to neoadjuvant chemoimmunotherapy (NCIT), highlighting the need for predictive bioma...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Open Access
Identification of ORF Virus in an Outbreak: A Molecular and Pathological Perspective
Artículo
Acceso abierto Artículo DOAJ
Nüvit Coşkun et al · Atatürk University · 2026 · ISSN 2822-3608
Orf virus causes infections in sheep and goats with lesions especially around muzzle and mouth. The disease is widespread, and most sheep-rearing countries are not free of infection. Disease is caused by ORF virus (ORFV)...
LCC TENDOlZldGVyaW5hcnkgbWVkaWNpbmU~Idioma eng
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Open Access
Lung cancer associated with cystic airspaces: Current concept, pathogenesis, imaging features, pathological basis, and management
Artículo
Acceso abierto Artículo DOAJ
Xin Xu et al · SAGE Publishing · 2026 · ISSN 2047-7163
This narrative review summarizes the current concept, CT imaging features, pathologic basis, and the correlation between imaging and pathology in lung cancer associated with cystic airspaces (LCCAs). Lung cancer associat...
LCC TENDOlNjaWVuY2U~; TENDOlRlY2hub2xvZ3k~Idioma eng
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Open Access
MRI features of craniopharyngiomas in different age groups and pathological subtypes
Artículo
Acceso abierto Artículo DOAJ
Weijian Wang et al · Frontiers Media S.A · 2026 · ISSN 2234-943X
ObjectiveTo investigate the MRI features of different pathological types in adult and juvenile patients with craniopharyngioma.Materials and methodsThe preoperative MRI images of 68 patients with pathologically confirmed...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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N-terminally acetylated Met11-Tau: a new pathological truncated Tau species with functional relevance in Alzheimer's disease
Artículo
Material complementario disponible Artículo DOAJ
Sarah Guedjdal et al · BMC · 2026 · ISSN 2047-9158
Abstract Background Tauopathies are a group of neurodegenerative diseases, including Alzheimer’s disease (AD), characterized by progressive accumulation of pathological Tau proteins. Among the diverse Tau species, trun...
LCC LCC:Neurology. Diseases of the nervous systemIdioma eng
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Overexpression of Circ_0004496 is Associated with Pathological Bone Formation in Ankylosing Spondylitis via the miR-145/ACTG1 Axis
Artículo
Acceso abierto Artículo DOAJ
Yu-Cong Zou et al · Trakya University · 2026 · ISSN 2146-3123
Background: The functional role of circular ribonucleic acids in ankylosing spondylitis (AS) remains poorly understood. In our previous study, circ_0004496 and actin gamma 1 (ACTG1) were found to be upregulated in ossifi...
LCC LCC:MedicineIdioma eng
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Open Access
The predictive role of Ki67 in pathological complete response (pCR) and invasive disease-free survival (IDFS) in HER2-positive breast cancer: a bi-centric retrospective cohort study of 244 cases
Artículo
Acceso abierto Artículo DOAJ
Laura Weydandt et al · Springer · 2026 · ISSN 1432-0711
Abstract Purpose The purpose of this study was to examine whether Ki67-scores have a predictive significance for pathological complete response (pCR) and invasive disease-free survival (IDFS) in HER2-positive breast canc...
LCC TENDOkd5bmVjb2xvZ3kgYW5kIG9ic3RldHJpY3M~Idioma eng
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Open Access
A 57-year-old male with diffuse astrocytoma in the lateral ventricle: case report
Artículo
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Juan Wang et al · BMC · 2026 · ISSN 1471-2377
Abstract Background Diffuse astrocytoma (DA) is the most common intraparenchymal brain tumor, primarily occurring in the frontal and temporal lobes. However, its occurrence in the lateral ventricles is rare. Case present...
LCC LCC:Neurology. Diseases of the nervous systemIdioma eng
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A retrospective analysis of risk-reducing salpingo-oophorectomy performed in women diagnosed with hereditary breast and ovarian cancer at our institution
Artículo
Acceso abierto Artículo DOAJ
Yusaku Shimizu et al · BMC · 2026 · ISSN 1897-4287
Abstract Background Hereditary breast and ovarian cancer (HBOC) confers a markedly increased lifetime risk of breast and ovarian cancers. As no effective surveillance method for early detection of ovarian cancer has been...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~; LCC:GeneticsIdioma eng
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Open Access
AI-driven saliency-guided retinal vessel segmentation framework for sustainable digital pathology
Artículo
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Rajib Guha Thakurta et al · Frontiers Media S.A · 2026 · ISSN 2296-858X
IntroductionAccurate segmentation of retinal blood vessels is essential for the early diagnosis of ophthalmic and systemic diseases such as diabetes, hypertension, and cardiovascular disorders. However, challenges such a...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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Anti-trypanosomal, anti-inflammatory, and neuroprotective effects of Cichorium intybus sesquiterpene lactones in experimental Trypanosoma evansi infection
Artículo
Material complementario disponible Artículo DOAJ
Marian G. Sawerus et al · Nature Portfolio · 2026 · ISSN 2045-2322
Abstract Trypanosoma evansi is an important protozoan pathogen affecting various animal species particularly camels and horses, leading to significant economic losses. The ineffective control of T. evansi is attributed t...
LCC LCC:Medicine; TENDOlNjaWVuY2U~Idioma eng
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Anticonvulsant and neuroprotective effects of jujuboside B on acute epilepsy
Artículo
Acceso abierto Artículo DOAJ
Wanruo Han et al · Shanghai Chinese Clinical Medicine Press Co., Ltd · 2026 · ISSN 1008-6358
Objective To investigate the alleviating effect of jujuboside B (JuB) on acute epilepsy in mice and its protective effect on hippocampal neurons. MethodsAn in vitro epilepsy model was established by stimulating primary h...
LCC LCC:MedicineIdioma eng
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Open Access
Association of PADUA and RENAL scores with early perioperative outcomes in large renal tumors managed with robot-assisted partial nephrectomy
Artículo
Acceso abierto Artículo DOAJ
Tunkut Doganca et al · Frontiers Media S.A · 2026 · ISSN 2296-875X
IntroductionTumor complexity scoring supports preoperative planning for robot-assisted partial nephrectomy (RAPN), but evidence in larger tumors is limited. We evaluated whether PADUA and RENAL nephrometry scores are ass...
LCC TENDOlN1cmdlcnk~Idioma eng
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Open Access
Bivalent nanovaccine MntC-rePO@LS conffers efective protections against Pseudomonas aeruginosa and Staphylococcus aureus
Tesis
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ZHAO Hui et al · Editorial Office of Journal of Army Medical University · 2026 · ISSN 2097-0927
Abstract Objective The escalating threat of antimicrobial resistance poses significant clinical challenges, particularly in cases of co-infections involving Staphylococcus aureus (SA) and Pseudomonas aeruginosa (PA), ...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma zho
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Case Report: Atypical pattern of pathologic response in cutaneous transdifferentiated melanoma with rhabdomyoblastic differentiation following neoadjuvant therapy
Artículo
Acceso abierto Artículo DOAJ
Isabela Paulino Serur et al · Frontiers Media S.A · 2026 · ISSN 2234-943X
Transdifferentiated melanoma is a rare variant of melanoma characterized by phenotypic plasticity, loss of conventional melanocytic markers, and acquisition of features from other tissue lineages, often associated with a...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Open Access
Deep Brain Stimulation Induces Antidepressant Effects by Restoring High‐Fidelity Communication in the BNST‐NAc Circuit
Artículo
Acceso abierto Artículo DOAJ
Xin Lv et al · Wiley · 2026 · ISSN 2198-3844
ABSTRACT Deep brain stimulation (DBS) for treatment‐resistant depression (TRD) is challenged by significant individual variability in efficacy and unclear neural circuit mechanisms. To address this, a cross‐species, ...
LCC TENDOlNjaWVuY2U~Idioma eng
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Dual-modality imaging enables longitudinal biodistribution profiling of intracerebroventricular CAR-T therapy in orthotopic glioma
Artículo
Material complementario disponible Artículo DOAJ
Chunzhao Li et al · Springer · 2026 · ISSN 1432-0851
Abstract Locoregional CAR-T delivery is increasingly explored for glioblastoma to improve intracranial tumor exposure; however, organ-level biodistribution kinetics after intracranial administration remain poorly quantif...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Early initiation of breastfeeding and immediate skin-to-skin contact are associated with lower hyperbilirubinemia risk in newborns from multifetal pregnancies
Artículo
Acceso abierto Artículo DOAJ
Miftahul Khairoh et al · Universitas Muhammadiyah Purwokerto · 2026 · ISSN 1693-7309
Background: Neonatal hyperbilirubinemia is a common condition and a major contributor to neonatal morbidity, particularly among infants from multifetal pregnancies who are at increased risk due to prematurity and low bir...
LCC LCC:MedicineIdioma eng
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Open Access
Effects and mechanisms of combined exposure to noise and microwave on hippocampal structure and function in mice
Artículo
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Chunxue LU et al · Editorial Committee of Journal of Environmental and Occupational Medicine · 2026 · ISSN 2095-9982
BackgroundCo-exposure to noise and microwave radiation occurs frequently. The central nervous system has been identified as a sensitive target organ for both noise and microwave exposure individually, and the underlying ...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~; TENDOlRveGljb2xvZ3kuIFBvaXNvbnM~Idioma eng
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Effects of Overload on Imiquimod‐Induced Psoriasis Model Mice: A Basic Experimental Study
Artículo
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Tomoki Furutani et al · Wiley · 2026 · ISSN 2398-8835
ABSTRACT Background and Aim Psoriasis is a skin disorder complicated by arthritis and enthesitis. The cytokines interleukin (IL)‐17, IL‐23, and tumor necrosis factor (TNF)‐α are reportedly key effectors of psorias...
LCC LCC:MedicineIdioma eng
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Efficacy of Bronchial Artery Infusion/Chemoembolization Combined with Platinum-Based Chemotherapy and PD-1 Inhibitor in Initially Unresectable Stage III Non-Small Cell Lung Cancer
Artículo
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Quan X et al · Dove Medical Press · 2026 · ISSN 1179-1322
Xiaoying Quan, Lei Lei, Xiaoyan Chen, Xiaoli Jia, Chunzhi Wu, Bin Ye, Qiyue Huang, Min Luo, Ning Wang, Jiayang Yu, Lifu Feng Department of Medical Oncology, the Sixth People’s Hospital of Chengdu, Chengdu, Sichuan, 610...
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