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Tumor microenvironment responsive nano-immunoregulator for precision cancer photodynamic immunotherapy
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Tumor microenvironment responsive nano-immunoregulator for precision cancer photodynamic immunotherapy
Xiaowei Chang et al · Elsevier · 2026 · ISSN 2590-0064
Spatiotemporally controlled reactive oxygen species (ROS) generation remains pivotal for advancing photodynamic immunotherapy. Herein, we present tumor microenvironment (TME)-responsive nano-immunoregulator featuring a C...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~; LCC:Biology (General)Idioma eng
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Tumor-Promoting Crosstalk of MMP11⁺ Fibroblasts and SPP1⁺ Macrophages Drive Poor Prognosis in Breast Cancer: Integrated Multi-Omics Analysis
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Tumor-Promoting Crosstalk of MMP11⁺ Fibroblasts and SPP1⁺ Macrophages Drive Poor Prognosis in Breast Cancer: Integrated Multi-Omics Analysis
Huang R et al · Dove Medical Press · 2026 · ISSN 2253-1556
Rongzhi Huang,1,* Zexu Zhan,1,* Shulin Huang,1 Wenlong Cao,1 Jiehua Li,1 Min Mao2 1Department of Gastrointestinal and Gland Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, T...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Tumor-targeted aptamer-conjugated engineered bacteria for CXCL9 cytokine delivery in non-small cell lung cancer immunotherapy
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Tumor-targeted aptamer-conjugated engineered bacteria for CXCL9 cytokine delivery in non-small cell lung cancer immunotherapy
Qinghao Gu et al · BMC · 2026 · ISSN 1479-5876
Abstract Background Bacterial cancer therapies have regained attention as a strategy to remodel the immunosuppressive tumor microenvironment (TME). Engineered bacteria equipped with tumor-targeting moieties can enhance i...
LCC LCC:MedicineIdioma eng
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Tumores pélvicos em mulheres na pós-menopausa Pelvic tumors in postmenopausal women
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Tumores pélvicos em mulheres na pós-menopausa Pelvic tumors in postmenopausal women
Francisco Cyro Reis de Campos Prado Filho et al · Federação Brasileira das Sociedades de Ginecologia e Obstetrícia · 1999 · ISSN 0100-7203
Objetivos: avaliar aspectos clínicos e ultra-sonográficos de tumores pélvicos na pós-menopausa e correlacioná-los com o diagnóstico final. Pacientes e Métodos: foram seguidas prospectivamente 36 mulheres menopausa...
LCC TENDOkd5bmVjb2xvZ3kgYW5kIG9ic3RldHJpY3M~Idioma eng
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A POSTN+ CAF/APOE+ TAM Axis is Associated with Tumor Progression and Potential Immunotherapy Resistance in Laryngeal Squamous Cell Carcinoma
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A POSTN+ CAF/APOE+ TAM Axis is Associated with Tumor Progression and Potential Immunotherapy Resistance in Laryngeal Squamous Cell Carcinoma
Ma K et al · Dove Medical Press · 2026 · ISSN 1178-7074
Kexin Ma, Jinqiao Tian, Hao Wu, Shuzheng Wang, Hao-Sheng Ni Department of Otolaryngology, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, Jiangsu, People’s Republic of ChinaCor...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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A paired multi-scale attention network for liver tumor segmentation in 99mTc-MAA SPECT/CT imaging
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A paired multi-scale attention network for liver tumor segmentation in 99mTc-MAA SPECT/CT imaging
Wanrat Limprapaipong et al · Nature Portfolio · 2025 · ISSN 2045-2322
Abstract Automatic liver tumor segmentation using Single-Photon Emission Computed Tomography/Computed Tomography (SPECT/CT) provides detailed insights that facilitate accurate tumor targeting and effective treatment plan...
LCC LCC:Medicine; TENDOlNjaWVuY2U~Idioma eng
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Ablative stereotactic MR-guided radiotherapy for >10 cm solid pseudopapillary tumor of the pancreas with liver oligometastases: a case report and literature review
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Ablative stereotactic MR-guided radiotherapy for >10 cm solid pseudopapillary tumor of the pancreas with liver oligometastases: a case report and literature review
Robert A. Herrera et al · Frontiers Media S.A · 2026 · ISSN 2234-943X
BackgroundSolid pseudopapillary tumors (SPTs) of the pancreas are rare, low-grade malignancies that generally have favorable outcomes when diagnosed at an early stage and can be resected. However, treatment options for p...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Analysis of the tumor reactivity of autologous TILs and allogeneic γδ T cells via tumor organoid–immune cell coculture
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Analysis of the tumor reactivity of autologous TILs and allogeneic γδ T cells via tumor organoid–immune cell coculture
Zijun Su et al · BMC · 2026 · ISSN 1479-5876
Abstract Background The efficacy of conventional αβ T cell-based immunotherapies is often limited by tumor immune evasion. γδ T cells can bypass these limitations through MHC-independent tumor recognition, but their ...
LCC LCC:MedicineIdioma eng
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Assessment of Tumor Infiltrating Lymphocytes in Breast Cancer Patients and its Correlation with Clinico- Histopathological Characteristics and Molecular Subtypes
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Assessment of Tumor Infiltrating Lymphocytes in Breast Cancer Patients and its Correlation with Clinico- Histopathological Characteristics and Molecular Subtypes
Nanda J Patil et al · Dr. Annil Mahajan · 2026 · ISSN 0972-1177
Background: Scoring of tumor infiltrating lymphocytes (TIL’s) in breast carcinoma specimens has gained increasing value as it has prognostic and predictive value in certain molecular subtypes of breast cancer especiall...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~; LCC:Internal medicineIdioma eng
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Baicalin suppresses colorectal cancer proliferation and induces M1 polarization of tumor-associated macrophages by promoting proteasomal degradation of HK2
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Baicalin suppresses colorectal cancer proliferation and induces M1 polarization of tumor-associated macrophages by promoting proteasomal degradation of HK2
Dong-hui Bai et al · Frontiers Media S.A · 2026 · ISSN 1664-3224
Colorectal cancer (CRC) ranks as the third most diagnosed cancer and the second leading cause of cancer-related mortality globally. Hexokinase II, a key rate-limiting enzyme in tumor glycolysis, is an important therapeut...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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C5orf46: a promising prognosis risk indicator with implication in the remodeling of KIRC and pan-cancer tumor microenvironments
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C5orf46: a promising prognosis risk indicator with implication in the remodeling of KIRC and pan-cancer tumor microenvironments
Lei Miao et al · Frontiers Media S.A · 2026 · ISSN 2234-943X
IntroductionC5orf46 is a recently discovered tumor-progression-related gene whose function in most cancers is still unknown, especially its potential role in regulating the tumor microenvironment (TME). The aim of the st...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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CMRA-DETR: a lightweight and high-accuracy detection framework for MRI-based brain tumor identification
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CMRA-DETR: a lightweight and high-accuracy detection framework for MRI-based brain tumor identification
Cai Weng et al · Frontiers Media S.A · 2026 · ISSN 2296-858X
IntroductionBrain tumor lesions in MRI images are characterized by low contrast, indistinct boundaries, and irregular morphology, posing substantial challenges for automated detection. RT-DETR provides an end-to-end, NMS...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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Differentiation of Microvessel Density Based on The Breast Cancer Patient Characteristics Including Age, Stage, Tumor Size, and Lymph Node MetastasisDifferentiation of Microvessel Density Based on The Breast Cancer Patient Characteristics Including Age, Stage, Tumor Size, and Lymph Node Metastasis
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Differentiation of Microvessel Density Based on The Breast Cancer Patient Characteristics Including Age, Stage, Tumor Size, and Lymph Node MetastasisDifferentiation of Microvessel Density Based on The Breast Cancer Patient Characteristics Including Age, Stage, Tumor Size, and Lymph Node Metastasis
Tasya Salsabila et al · Dharmais Cancer Hospital - National Cancer Center · 2024 · ISSN 1978-3744
Background: Breast cancer is the most common malignant tumor in the world and Indonesia. One well-known prognostic marker is microvessel density (MVD), the numerical value of angiogenesis. In recent years, it has been re...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Epstein–Barr virus-associated smooth muscle tumor of the lung in a child: a case report and literature review
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Epstein–Barr virus-associated smooth muscle tumor of the lung in a child: a case report and literature review
Xuelian Chang et al · Frontiers Media S.A · 2026 · ISSN 2296-858X
BackgroundPulmonary Epstein–Barr virus-associated smooth muscle tumor (EBV-SMT) is extremely rare in children with congenital immunodeficiency. This case report describes the clinical details of a pediatric pulmonary E...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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Eritrocitose associada a tumor venéreo transmissível em cão: relato de caso Erythrocytosis in a dog with transmissible venereal tumor: case report
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Eritrocitose associada a tumor venéreo transmissível em cão: relato de caso Erythrocytosis in a dog with transmissible venereal tumor: case report
R. Duarte et al · Universidade Federal de Minas Gerais, Escola de Veterinária · 2006 · ISSN 0102-0935
Descreve-se um caso de eritrocitose absoluta (hematócrito: 74%, hemoglobina: 24,2g/dl) em um cão com tumor venéreo transmissível cutâneo. A concentração de hemoglobina e o hematócrito retornaram ao valor normal a...
LCC LCC:Animal cultureIdioma eng
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Folate metabolism–based risk stratification identifies CYP27B1 as a determinant of tumor progression in HNSCC
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Folate metabolism–based risk stratification identifies CYP27B1 as a determinant of tumor progression in HNSCC
Kai Zhang et al · Frontiers Media S.A · 2026 · ISSN 2296-858X
Head and neck squamous cell carcinoma (HNSCC) is characterized by frequent recurrence and poor survival, highlighting the need for reliable biomarkers for risk stratification and therapeutic guidance. Folate-mediated one...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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Glycemic variability associated with gamma secretase inhibitor therapy in a type 1 diabetic patient undergoing treatment for desmoid tumor: a case report
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Glycemic variability associated with gamma secretase inhibitor therapy in a type 1 diabetic patient undergoing treatment for desmoid tumor: a case report
Jean Carlos Ramos Cardona et al · Frontiers Media S.A · 2026 · ISSN 1664-2392
IntroductionDesmoid tumors, also known as aggressive fibromatosis, are rare, locally invasive soft tissue neoplasms characterized by clonal fibroblastic proliferation without metastatic potential. Gamma secretase inhibit...
LCC LCC:Diseases of the endocrine glands. Clinical endocrinologyIdioma eng
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Immunological impact of tumor-draining lymph node dissection on systemic Th1-like CD4+ T cells in patients with early-stage lung cancer
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Immunological impact of tumor-draining lymph node dissection on systemic Th1-like CD4+ T cells in patients with early-stage lung cancer
Atsushi Kamigaichi et al · Springer · 2026 · ISSN 1432-0851
Abstract Introduction Tumor-draining lymph nodes (LNs) are critical for initiating and maintaining antitumor immunity. However, systematic LN dissection (LND) remains the standard surgical procedure for lung cancer. This...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Implant survival and factors associated with failure of cemented custom-made distal femoral megaprostheses after tumor resection
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Implant survival and factors associated with failure of cemented custom-made distal femoral megaprostheses after tumor resection
Apostolopoulos Vasileios et al · EDP Sciences · 2026 · ISSN 2426-8887
Background: Distal femoral megaprosthetic reconstruction is a standard limb-salvage procedure after tumor resection. This study aimed to evaluate implant survival and associated factors, the incidence of mechanical failu...
LCC TENDOk9ydGhvcGVkaWMgc3VyZ2VyeQ~~Idioma eng
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Is Surgical Treatment an Option for Locally Advanced Cervical Cancer in the Presence of Central Residual Tumor after Chemoradiotherapy?
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Is Surgical Treatment an Option for Locally Advanced Cervical Cancer in the Presence of Central Residual Tumor after Chemoradiotherapy?
Samet Topuz et al · Federação Brasileira das Sociedades de Ginecologia e Obstetrícia · 2020 · ISSN 0100-7203
Abstract Objective To evaluate the outcomes of surgical treatment in patients with chemoradiotherapy (CRT)-resistant and locally advanced cervical cancer (LACC). Methods Patients with LACC who underwent surgery due t...
LCC TENDOkd5bmVjb2xvZ3kgYW5kIG9ic3RldHJpY3M~Idioma eng
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Kint3-4 promotes apoptosis and inhibition of angiogenesis in solid Ehrlich Tumor
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Kint3-4 promotes apoptosis and inhibition of angiogenesis in solid Ehrlich Tumor
C Souza et al · Universidade Federal de Minas Gerais, Escola de Veterinária · 2012 · ISSN 1678-4162
A proteína Kint3-4 (PKint3-4), codificadora da angiostatina, é reconhecida por sua potencialidade antiangiogênica. O presente estudo teve como objetivo avaliar o efeito da proteína Kint3-4 no crescimento do tumor só...
LCC LCC:Animal cultureIdioma eng
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Lung Tumor Segmentation in Medical Imaging Using U-NET
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Lung Tumor Segmentation in Medical Imaging Using U-NET
J Jayapradha et al · MMU Press · 2025 · ISSN 2821-370X
Tumors are a deadly condition often triggered by a range of abnormal modifications and genetic abnormalities. Early tumor diagnosis is essential due to the highly concerned nature of the disease. Early detection and trea...
LCC LCC:Electronic computers. Computer science; TENDOkluZm9ybWF0aW9uIHRlY2hub2xvZ3k~Idioma eng
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Machine learning vs. radiomics for discriminating atypical cartilaginous tumors from benign enchondromas on MRI
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Machine learning vs. radiomics for discriminating atypical cartilaginous tumors from benign enchondromas on MRI
Simon Johannes Joham et al · BMC · 2026 · ISSN 1475-925X
Abstract Background Enchondromas (EC) present cartilaginous tumors that are difficult to differentiate from their intermediate counterpart, atypical cartilaginous tumors (ACT). Histologically, tumor distinction of these ...
LCC TENDOk1lZGljYWwgdGVjaG5vbG9neQ~~Idioma eng
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Neutrophil extracellular traps in the tumor microenvironment, metastasis, therapy, and beyond: advances, challenges, and perspectives
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Neutrophil extracellular traps in the tumor microenvironment, metastasis, therapy, and beyond: advances, challenges, and perspectives
Jingwen He et al · BMC · 2026 · ISSN 1756-8722
Abstract Neutrophil extracellular traps (NETs), the DNA-protein structures released by neutrophils within the tumor microenvironment (TME), play a role in cancer that extends far beyond their traditional antimicrobial fu...
LCC TENDOkRpc2Vhc2VzIG9mIHRoZSBibG9vZCBhbmQgYmxvb2QtZm9ybWluZyBvcmdhbnM~; TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHIdioma eng
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