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Abstract Background Optimization of biotechnological processes is traditionally limited by time-consuming trial-and-error approaches and the complexity of simultaneously optimizing multiple, often conflicting objectives....

Abstract In this study, we propose a novel biosensor based on a hexagonal-shaped microcavity with two slot waveguides within a two-dimensional photonic crystal. The biosensor aims to detect various blood components by ut...

Lead optimization (LO) is essential to fulfill the efficacy and safety requirements of drug-based targeted therapy. The ease with which water may be locally removed from around the target protein crucially influences LO ...

Abstract Investigations into aviation accidents aim to identify root causes and enhance safety. Despite advancements in safety measures, technology, and education, general aviation accident rates remain stable, with los...

Abstract High-electron-mobility transistors (HEMTs) based on wide bandgap (WBG) materials like gallium nitride (GaN) are vital for next-generation power electronics and high-frequency applications, offering high breakdow...

The increasing complexity of pharmaceutical management in pharmacies demands efficient systems to streamline drug classification and inventory control. As pharmacies handle a diverse range of formulations, including tabl...

BackgroundAutistic children experience enduring difficulties with emotion regulation and daily participation. Emotion-oriented play-learning tools (EPLTs, sensory play-learning tools for supporting emotion and self-regul...

Abstract Large Language Models (LLMs) and Retrieval-Augmented Generation (RAG) systems have significantly advanced data modelling capabilities and improved opportunities for extracting knowledge from vast and heterogeneo...

Construction generates substantial material waste with environmental and economic impacts, yet current methods rarely integrate waste estimation with project schedules. This study develops and validates semi-automated 4D...

Advanced Air Mobility (AAM) uses electric vertical take-off and landing (eVTOL) vehicles to address urban congestion and emissions. However, corridor design, operation management, and separation standards remain underexa...

This paper investigates time-domain layered division multiplexing for coexistence between legacy Integrated Services Digital Broadcasting–Terrestrial and an enhanced terrestrial broadcast service within the same 6...

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Background and Objectives: The driving forces of productivity-oriented design management in architecture and urban planning offices, as a novel approach to improving project performance, focus on identifying and analyzin...

Advanced geological prediction is one essential part in tunnel construction, and 3D E-SCAN resistivity device is introduced. In this device, the current and measuring electrodes are arranged on the tunnel face, which can...

The rapid growth of Internet of Things (IoT) devices, including smartwatches, home assistants, and connected appliances, has brought significant convenience to daily life, but it has also introduced serious security chal...

In the current environment there is a growing need for rapid development of advanced manufacturing technologies. The complexity of such projects requires the integration of work from various technical specialties. If t...

Aging causes changes that affect functioning of cognitive processes such as cognitive flexibility (CF). Given it allows changing both behavior and thinking in dynamic contexts, it constitutes an essential trait of adapti...

This study investigates whether a culturally immersive pedagogy can measurably enhance advanced Arabic speaking proficiency among non-native learners within the CEFR framework. Using a quasi-experimental design at King S...

This article examines how bicameral institutional design shapes legislative cohesion in a presidential democracy. Differences in time horizon, electoral calendars and the legislative importance of bills generate systemat...

Advanced materials, serving as the core material foundation underpinning economic transformation, national defense security, and technological revolution, directly determine national competitiveness through their researc...

Synthetic biology is emerging as a frontier interdisciplinary discipline that is increasingly regarded as a key driver of sustainable innovation in advanced materials. By leveraging the design-build-test-learn (DBTL) cyc...

Abstract Parasitic diseases such as malaria, leishmaniasis, and schistosomiasis remain difficult to treat due to the pathogens’ complex life cycles, intracellular niches, and resistance to conventional therapies. Tradi...

The unusual electromagnetic responses of nanostructured metasurfaces endow them with an ability to manipulate the four fundamental properties (amplitude, phase, polarization, and frequency) of lightwave at the subwavelen...

Italian historic centres face critical challenges balancing heritage conservation with contemporary needs, particularly in regions like Calabria where smaller settlements experience depopulation, decay, and inadequate se...