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Materias / palabras clave: arthritis, musculoskeletal conditions, rheumatic conditions; Medicine: Internal medicine: Specialties of internal medicine: Diseases of the musculoskeletal system

Abstract Objectives To develop and evaluate a deep learning model for diagnosing untreated rheumatoid arthritis (RA) using digital camera images of bilateral dorsal hands, benchmarking its performance against the widely-...

Increase in the relative risk of development of secondary malignancy in patients with rheumatoid arthritis (RA) have been demonstrated, possibly either due to underlying immunological disorders, or to cytotoxic drugs use...

ABSTRACT Objectives To evaluate whether glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) are associated with improved survival and renal outcomes in patients with rheumatoid arthritis and type 2 diabetes, a po...

Background: Emerging evidence has shown that exposure to polycyclic aromatic hydrocarbons (PAHs) is a risk factor for rheumatoid arthritis (RA). Benzo[a]pyrene (BaP), a representative PAH congener, exacerbates the develo...

Septic arthritis is rarely seen in transplant patients and differs from the general population with regards to gram negative and/or atypical agents being the prominent causes. In renal transplant patients, osteonecrosis ...

Capsaicin (CAP), the pungent compound in chili peppers, is well-known for its anti-inflammatory properties, yet its role in autoimmune immunometabolism remains unexplored. In a murine model of Collagen-Induced Arthritis,...

Abstract Background The newly discovered Treg subset (CLA+ Tregs) expressing cutaneous lymphocyte-associated antigen is associated with inflammatory conditions. This study elucidated the role of CLA+ Tregs in rheumatoid ...

Abstract Rheumatoid arthritis (RA) and osteoarthritis (OA) are prevalent chronic joint diseases characterized by persistent inflammation, progressive cartilage degeneration, and impaired tissue repair mechanisms. While i...

Galectins, a family of animal lectins, play central roles in immune system regulation, shaping both innate and adaptive responses in physiological and pathological processes. These include rheumatoid arthritis (RA), a ch...

Dendritic cells (DCs) participate in the pathogenesis of several diseases. We investigated DCs and the connection between mucosa and joints in a murine model of Yersinia enterocolitica O:3-induced reactive arthritis (ReA...

BackgroundPatients with rheumatoid arthritis (RA) and concomitant fibromyalgia (FM) frequently experience severe, refractory pain, elevated disease activity scores, and substantial psychological distress. Conventional tr...

Rheumatoid arthritis (RA) is an autoimmune disease that causes chronic synovial inflammation, progressive cartilage destruction, and bone erosion. Although there have been significant improvements in the use of conventio...

Background: Epstein Barr Virus (EBV) infection has been associated with the Rheumatoid Arthritis (RA) etiopathology, thus, considering it a relevant etiological agent in the disease development. We have previously observ...

Abstract Background Frunevetmab, a felinized antinerve growth factor monoclonal antibody, effectively decreases osteoarthritis (OA) pain in cats. Objective To evaluate the efficacy of frunevetmab given at monthly interva...

Abstract Glucocorticoid (GC) use in rheumatoid arthritis (RA) remains concerning due to adverse effects. Janus kinase inhibitors (JAKi) may enable GC reduction or discontinuation. This study examined factors associated w...

Background: Rheumatoid arthritis (RA) causes structural changes and inflammatory responses which damage the knee tissues that include the cruciate ligaments. Scientists will gain knowledge about ligament involvement in c...

Abstract Juvenile idiopathic arthritis (JIA) comprises a heterogeneous group of childhood-onset inflammatory arthritides that remain challenging to treat. An expanding range of biologic and targeted synthetic disease-mod...

The prevalence of caprine arthritis-encephalitis (CAE) infection in dairy goat herds from Rio Grande do Norte State, Brazil, was estimated, and the predisposing factors to the infection were identified. An epidemiologic ...

OBJETIVO: Estudar se a artrite reumatoide (AR) sofre influências de idade de menarca, número de gestações e tempo de vida reprodutiva. MÉTODOS: Estudo transversal e retrospectivo dos prontuários de 247 pacientes co...

Abstract Background The dysfunction of osteoblasts has been identified as a pivotal contributor to bone erosion in rheumatoid arthritis (RA). Emerging evidence shows long non-coding RNAs (lncRNAs) as important regulators...

Abstract Background Musculoskeletal diseases, such as Juvenile Idiopathic Arthritis (JIA), can lead to altered joint mobility and changes in gait pattern. While marker-based motion capture systems are considered the gold...

Targeted B-cell depletion via the anti-CD20 monoclonal antibody rituximab fundamentally altered the therapeutic algorithm for rheumatoid arthritis (RA). Despite its clinical entrenchment, approximately 40% of patients ex...

Articular infections which caused by microorganisms are called as septic arthritis. Septic arthritis usually is not observed in healthy persons. Generally, it develops in patients with end-stage renal disease (ESRD), rhe...