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HueTools: A modular image processing and ML toolkit for quantitative colorimetric assay development
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HueTools: A modular image processing and ML toolkit for quantitative colorimetric assay development
Prava Sharma et al · Elsevier · 2026 · ISSN 2472-6303
Colorimetric assays offer a low-cost, accessible means of diagnostic testing but often suffer from subjective interpretation and variability caused by inconsistent imaging conditions. To address these challenges, we pres...
LCC TENDOkJpb3RlY2hub2xvZ3k~; TENDOk1lZGljYWwgdGVjaG5vbG9neQ~~Idioma eng
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Development and evaluation of an assay for the detection of tick-borne encephalitis virus RNA via real-time PCR with reverse transcription
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Development and evaluation of an assay for the detection of tick-borne encephalitis virus RNA via real-time PCR with reverse transcription
Alena Sharova et al · BMC · 2026 · ISSN 1756-3305
Abstract Background Tick-borne encephalitis virus (TBEV, Orthoflavivirus encephalitidis) is an arbovirus of the family Flaviviridae. It is the etiological agent of tick-borne encephalitis (TBE), a severe disease affectin...
LCC TENDOkluZmVjdGlvdXMgYW5kIHBhcmFzaXRpYyBkaXNlYXNlcw~~Idioma eng
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Development of a novel duplex recombinase polymerase amplification (DRPA) assay for rapid detection of carbapenem-resistant Acinetobacter baumannii
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Development of a novel duplex recombinase polymerase amplification (DRPA) assay for rapid detection of carbapenem-resistant Acinetobacter baumannii
Chenyan Yuan et al · BMC · 2026 · ISSN 1471-2334
Abstract Carbapenem-Resistant Acinetobacter baumannii (CRAB) poses a major public health threat due to its multidrug resistance and high mortality rates, necessitating rapid and accurate diagnostic tools for timely inter...
LCC TENDOkluZmVjdGlvdXMgYW5kIHBhcmFzaXRpYyBkaXNlYXNlcw~~Idioma eng
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Development of sandwich ELISA for detection of soybean allergens β-Conglycinin and glycinin
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Development of sandwich ELISA for detection of soybean allergens β-Conglycinin and glycinin
XIAO Haoran et al · The Editorial Office of Chinese Journal of Food Hygiene · 2025 · ISSN 1004-8456
ObjectiveIn this study， we established sandwich enzyme-linked immunosorbent assay （sELISA） methods to detect major soybean allergens β-Conglycinin and glycinin.MethodsA single-factor experiment was conducted to op...
LCC TENDOkZvb2QgcHJvY2Vzc2luZyBhbmQgbWFudWZhY3R1cmU~; LCC:Nutrition. Foods and food supplyIdioma zho
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Development and Structural Characterization of UTE‐156, a Covalent Inhibitor of the VCP/p97 AAA+ ATPase
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Development and Structural Characterization of UTE‐156, a Covalent Inhibitor of the VCP/p97 AAA+ ATPase
Daniela Tamayo‐Jaramillo et al · Wiley · 2026 · ISSN 2198-3844
ABSTRACT The AAA+ ATPase valosin‐containing protein (VCP/p97) is a central regulator of protein homeostasis that is well characterized for its role in extracting and remodeling ubiquitinated substrates. Dysregulation o...
LCC TENDOlNjaWVuY2U~Idioma eng
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Development of a novel hybrid alphavirus-Nipah virus pseudovirion for rapid quantification of vaccine-induced neutralization antibodies
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Development of a novel hybrid alphavirus-Nipah virus pseudovirion for rapid quantification of vaccine-induced neutralization antibodies
Brian Hetrick et al · Taylor & Francis Group · 2026 · ISSN 2222-1751
Nipah virus (NiV) is an emergent paramyxovirus that causes serious disease in humans and animals. Accurate quantification of neutralizing antibodies (nAB) against NiV is essential for vaccine development. The current sta...
LCC TENDOkluZmVjdGlvdXMgYW5kIHBhcmFzaXRpYyBkaXNlYXNlcw~~; TENDOk1pY3JvYmlvbG9neQ~~Idioma eng
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Development and validation of a high performance liquid 4 chromatography method for oligodeoxynucleotides determination 5 in a novel coagel-based formulation
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Development and validation of a high performance liquid 4 chromatography method for oligodeoxynucleotides determination 5 in a novel coagel-based formulation
Ullio Gamboa, Gabriela Veronica et al · Elsevier · 2015 · ISSN 2214-1812
The therapeutic benefit of phosphorothioate oligodeoxynucleotides (PS-ODN) containing immune stimulatory sequences has been demonstrated in animal models of cancer and infection. Several tools are available for the deter...
Idioma eng
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Development of ready-to-use tranexamic acid gauze as a hemostatic material for oral surgery: fabrication, hemostasis, and shelf-life
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Development of ready-to-use tranexamic acid gauze as a hemostatic material for oral surgery: fabrication, hemostasis, and shelf-life
Taechana Sitthikornvanich et al · BMC · 2026 · ISSN 1472-6831
Abstract Background Postoperative hemorrhage is one of the major complications of oral surgery. Conventional hemostatic methods, such as chair-side preparation of tranexamic acid (TXA)-soaked gauze or TXA mouthwash, ofte...
LCC TENDOkRlbnRpc3RyeQ~~Idioma eng
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Production of monoclonal antibodies and development of a quantitative immuno-polymerase chain reaction assay to detect and quantify recombinant Glutathione S-transferase
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Production of monoclonal antibodies and development of a quantitative immuno-polymerase chain reaction assay to detect and quantify recombinant Glutathione S-transferase
Abud, Julián Elías et al · Academic Press Inc Elsevier Science · 2017 · ISSN 1046-5928
GST-tagged proteins are important tools for the production of recombinant proteins. Removal of GST tag from its fusion protein, frequently by harsh chemical treatments or proteolytic methods, is often required. Thus, the...
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Assessment of the Genotoxic Effect of Pesticide (Profenophos and Cypermethrin) on Allium Cepa L. through Comet Assay
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Assessment of the Genotoxic Effect of Pesticide (Profenophos and Cypermethrin) on Allium Cepa L. through Comet Assay
Ali Hasnian et al · Wright State University · 2024 · ISSN 2309-3854
Pesticides are specially designed to control pests and help in increasing the yield of crops. This study aims to investigate the genotoxic effect of the major ingredients of commonly used pesticides (Profenophos and Cype...
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Digestibilidade aparente e desenvolvimento de eqüinos em crescimento submetidos a dietas compostas por diferentes níveis de substituição do feno de Tifton 85 pela casca de soja Apparent digestibility and development of growing horses fed diets with different levels of substitution of Tifton 85 hay for soybean hulls
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Digestibilidade aparente e desenvolvimento de eqüinos em crescimento submetidos a dietas compostas por diferentes níveis de substituição do feno de Tifton 85 pela casca de soja Apparent digestibility and development of growing horses fed diets with different levels of substitution of Tifton 85 hay for soybean hulls
João Batista da Silva Quadros et al · Sociedade Brasileira de Zootecnia · 2004 · ISSN 1516-3598
Dois experimentos foram conduzidos com o objetivo de avaliar nutricionalmente a utilização da casca de soja na alimentação de eqüinos em crescimento. Foram utilizadas quatro dietas, uma ração testemunha e três di...
LCC LCC:Animal cultureIdioma eng
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Galactose alters early-life development and exerts sex-specific nutritional programming effects on lifespan in Drosophila melanogaster
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Galactose alters early-life development and exerts sex-specific nutritional programming effects on lifespan in Drosophila melanogaster
Peixin Sun et al · Frontiers Media S.A · 2026 · ISSN 2296-861X
BackgroundNutritional programming by early-life nutrition exerts long-lasting effects on later-life health. In mammals, galactose, as a component of the milk sugar lactose, is consumed during lactation. Mouse studies sug...
LCC LCC:Nutrition. Foods and food supplyIdioma eng
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A Systems-Predicted Neutralizing Antibody Assay Identifies Compartment-Specific Features Correlating with Neutralization Breadth
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A Systems-Predicted Neutralizing Antibody Assay Identifies Compartment-Specific Features Correlating with Neutralization Breadth
Qixin Wang et al · Rockefeller University Press · 2026 · ISSN 3065-8993
Quantifying neutralizing antibody levels across anatomical sites and understanding correlates of neutralization breadth is paramount for monoclonal antibody treatments and next-generation vaccination strategies. The syst...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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DNA fragmentation, transgene expression and embryo development after intracytoplasmic injection of DNA-liposome complexes in IVF bovine zygotes
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DNA fragmentation, transgene expression and embryo development after intracytoplasmic injection of DNA-liposome complexes in IVF bovine zygotes
Vichera, G. et al · Cambridge University Press · 2012 · ISSN 0967-1994
Summary This study was designed to evaluate the quality and viability of bovine embryos produced by in vitro fertilization (IVF), after intracytoplasmic injection of pCX-EGFP-liposome complexes or pBCKIP2.8-liposome comp...
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Drug repurposing screening validated by experimental assays identifies two clinical drugs targeting SARS-CoV-2 main protease
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Drug repurposing screening validated by experimental assays identifies two clinical drugs targeting SARS-CoV-2 main protease
Prada Gori, Denis Nihuel et al · Frontiers Media · 2023 · ISSN 2674-0338
The COVID-19 pandemic prompted several drug repositioning initiatives with the aim to rapidly deliver pharmacological candidates able to reduce SARS-CoV-2 dissemination and mortality. A major issue shared by many of the ...
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Integrated transcriptomics, proteomics, and metabolomics analyses reveal key regulatory pathways related to the development of viral symptoms in tomato plants
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Integrated transcriptomics, proteomics, and metabolomics analyses reveal key regulatory pathways related to the development of viral symptoms in tomato plants
Kaijie Shang et al · BMC · 2026 · ISSN 1471-2229
Abstract Background Viral infections of tomato plants present a significant threat to tomato production and yield. Mixed viral infections are common in field-grown tomatoes and are known to exacerbate disease symptoms; h...
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Immunodiagnosis of cystic echinococcosis in livestock: Development and validation dataset of an ELISA test using a recombinant B8/2 subunit of Echinococcus granulosus sensu lato
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Immunodiagnosis of cystic echinococcosis in livestock: Development and validation dataset of an ELISA test using a recombinant B8/2 subunit of Echinococcus granulosus sensu lato
Poggio, Thelma Veronica et al · Elsevier · 2022 · ISSN 2352-3409
The accuracy of screening tests for detecting cystic echinococcosis (CE) in livestock depends on characteristics of the host–parasite interaction and the extent of serological cross-reactivity with other taeniid specie...
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In vitro assessment of foot-and-mouth disease vaccine immunogenicity: advances, challenges, and ethical considerations
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In vitro assessment of foot-and-mouth disease vaccine immunogenicity: advances, challenges, and ethical considerations
Lebogang Othusitse et al · Frontiers Media S.A · 2026 · ISSN 2297-1769
Vaccination is widely used to control foot-and-mouth disease (FMD), necessitating robust approaches for evaluating vaccine potency to ensure a consistent supply of effective and safe vaccines. Traditional (in vivo) poten...
LCC TENDOlZldGVyaW5hcnkgbWVkaWNpbmU~Idioma eng
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Acute and chronic toxicity of copper and chromium to the freshwater calanoid copeppod Notodiaptomus conifer (SARS).
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Acute and chronic toxicity of copper and chromium to the freshwater calanoid copeppod Notodiaptomus conifer (SARS).
Gutierrez, Marìa Florencia et al · Springer · 2010 · ISSN 0049-6979
Recent studies have shown that the lower basin of the Salado River is highly polluted with copper and chromium.  In order to evaluate the effect of those metals on Notodiaptomus conifer, a representative calanoid copepo...
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Determination of progesterone (P4) from bovine serum samples using a microfluidic immunosensor system
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Determination of progesterone (P4) from bovine serum samples using a microfluidic immunosensor system
Arevalo, Fernando Javier et al · Elsevier Science · 2010 · ISSN 1986-1992
Progesterone (P4) is a steroidal hormone with a vital role in the maintenance of human and animal health. This paper describes the development of an immunosensor coupled to glassy carbon (GC) electrode and integrated to ...
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Enhanced production of cytotoxic secondary metabolites through garlic peel biotransformation using Paecilomyces maximusPQ584815
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Enhanced production of cytotoxic secondary metabolites through garlic peel biotransformation using Paecilomyces maximusPQ584815
Dina Mahfouz Eskander et al · BMC · 2026 · ISSN 2661-8974
Abstract Research on garlic peel has identified a variety of bioactive compounds. This study highlights the significance of garlic peels and the marine fungal strain Paecilomycesmaximus PQ584815 in generating secondary m...
LCC LCC:Nutrition. Foods and food supply; TENDOkZvb2QgcHJvY2Vzc2luZyBhbmQgbWFudWZhY3R1cmU~Idioma eng
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FDA 2025 Cancer Drug Approvals: targeted therapy dominates
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FDA 2025 Cancer Drug Approvals: targeted therapy dominates
Jan Trøst Jørgensen · Open Exploration Publishing Inc · 2026 · ISSN 2692-3114
This commentary discusses the FDA’s drug approvals in 2025, with a particular focus on cancer therapies and the role of companion diagnostics (CDx). Cancer has emerged as the leading therapeutic area, accounting for 35...
LCC LCC:Internal medicineIdioma eng
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Imaging transcription factors dynamics with advanced fluorescence microscopy methods
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Imaging transcription factors dynamics with advanced fluorescence microscopy methods
Verneri, Paula et al · Elsevier Science · 2018 · ISSN 0925-4773
Pluripotent stem cells (PSCs) are capable of self-renewing and producing all cell types derived from the three germ layers in response to developmental cues, constituting an important promise for regenerative medicine. P...
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Impact of the CYFIP2 R87C variant in a human neuronal model in vitro
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Impact of the CYFIP2 R87C variant in a human neuronal model in vitro
Isabelle Zaboroski-Silva et al · Nature Portfolio · 2026 · ISSN 2045-2322
Abstract Mutations in the CYFIP2 gene, particularly the R87C variant, are associated with severe epileptic encephalopathy, and present challenges for therapeutic development. This study utilized CRISPR/Cas9-edited human ...
LCC LCC:Medicine; TENDOlNjaWVuY2U~Idioma eng
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