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IntroductionOrthopedic implant-associated infections, predominantly caused by S. aureus, pose significant challenges due to biofilm formation and antibiotic resistance. Bioactive Glass (BAG) S53P4 is a unique material wi...

Surface adhesion is critical to the survival of pathogenic bacteria both in natural niches and during infections, often via forming matrix-embedded communities called biofilms. Vibrio cholerae, the causal agent of pandem...

Mobile genetic elements (MGEs) such as bacteriophages and plasmids profoundly shape microbial community structure and drive horizontal gene transfer across ecosystems. Wastewater treatment systems, with their high cell d...

Ziye Liu,1 Meiyu Deng,2 Bu Wang,2 Jianhua Liu,2 Wei Zhang,3,* Jianqing Zhao2,* 1Department of Respiratory Medicine, The First School of Clinical Medicine, Hebei North University, Zhangjiakou, Hebei, Peopl...

ABSTRACT Biofilms play a crucial role in medical, industrial, and environmental microbiology, yet their structural complexity often makes them challenging to study in undergraduate teaching laboratories. We present a sim...

Abstract Background To compare the antibacterial activity of conventional intracanal medicaments used in regenerative endodontic treatment (TAP, DAP, Ca(OH)₂, CHX gel) with novel hydrogel-based formulations (chitosan, ...

One way that pathogens develop resistance to pharmaceuticals is by forming biofilms, which are 3-D communities of bacteria. As a result, there is considerable interest in identifying new antibiofilm agents from nature th...

Ensuring microbial safety in drinking water remains a challenge, particularly for ageing infrastructure and complex treatment processes. Because water treatment works sit at the interface between source-water ecosystem i...

Periodontitis, a chronic inflammatory disease induced by pathogenic microorganisms. Effective management requires the elimination of plaque biofilms, the suppression of oxidative stress, and the regeneration of periodont...

Abstract Background Staphylococcus aureus skin infections represent a persistent clinical challenge owing to their high pathogenicity, multidrug resistance, and biofilm-associated recurrence, which collectively impair an...

Abstract Background The objective of this in vitro study was to assess the anti-biofilm efficacy of super-oxidized water and ozonated water, activated through various methods, against Enterococcus faecalis (E. faecalis) ...

Abstract Background After resection surgery, recurrence occurs in more than 30% of colorectal cancer (CRC) patients. Previous studies have highlighted the role of the gut microbiota in CRC initiation and progression; how...

Abstract Background The global rise of extensively drug-resistant Acinetobacter baumannii, particularly biofilm-forming strains, has drastically limited treatment options and created an urgent need for novel therapies to...

BackgroundStreptococcus canis is an emerging zoonotic pathogen capable of causing infective endocarditis (IE) in animals and humans. In IE, bacterial biofilms form vegetations on heart valves, protecting microbes from a...

Abstract Alcoholic Heart Disease (AHD) involves gut microbiota dysbiosis, metabolic disturbances, and circadian disruption, yet their interconnections remain unclear. Using a murine AHD model, we integrated echocardiogra...

Abstract Preterm birth is the leading cause of neonatal morbidity and mortality, particularly in low- and middle-income countries. The vaginal microbiome influences pregnancy outcomes by effecting immunity, epithelial in...