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Materias / palabras clave: Science; General; Ciencias; Biotechnology; Biotecnología

Objective Endometriosis (EMs) is a chronic gynaecological condition characterised by the ectopic growth of endometrial tissue; however, its molecular mechanisms remain insufficiently understood. Ferroptosis, an iron-depe...

Materias / palabras clave: bioinformatics, computational biology; Medicine: Medicine (General): Computer applications to medicine. Medical informatics; Science: Biology (General)

Background: Liver hepatocellular carcinoma is a highly prevalent and lethal malignancy. The orphan cytokine receptor-like factor 3, although evolutionarily conserved and implicated in hematopoiesis and neuroprotection, r...

Abstract Background Carotid atherosclerosis is a kind of systemic atherosclerosis in the carotid arteries. It remains one of the leading causes of ischemic stroke. However, the efficiency of treatment is insufficient. Th...

Abstract Objective This study aimed to investigate the effect of miRNAs differentially expressed in serum exosomes on endothelial cells after myocardial infarction. Design & methods Specific pathogen-free male Sprague–...

Abstract Background Head and neck squamous cell carcinoma (HNSCC) is a prevalent and aggressive malignancy with limited prognostic markers. Ubiquitin-specific peptidase 33 (USP33) has emerged as a potential modulator of ...

Materias / palabras clave: bioinformatics, computational biology; Medicine: Medicine (General): Computer applications to medicine. Medical informatics; Science: Biology (General)

Materias / palabras clave: bioinformatics, computational biology, systems biology, molecular biology, evolutionary biology; Science: Biology (General)

Materias / palabras clave: data visualisation, integrative bioinformatics, genomics, computational bioimaging; Medicine: Medicine (General): Computer applications to medicine. Medical informatics

Materias / palabras clave: genomics, proteomics, bioinformatics, epigenomics; Science: Biology (General); Medicine: Medicine (General): Computer applications to medicine. Medical informatics

Materias / palabras clave: bioinformatics, biotechnology, mathematical modelling, genomic variation, pathology, algorithms; Technology: Chemical technology: Biotechnology; Science: Biology (General)

Materias / palabras clave: bioinformatics, computational biology, genomics, gene expression, genetic and population analysis, data and text mining; Science: Biology (General): Genetics

Materias / palabras clave: genomics, proteomics, transcriptomics, epigenetics, bioinformatics; Medicine: Medicine (General): Computer applications to medicine. Medical informatics; Science: Biology (General): Genetics

Abstract Infectious disease diagnostics has been transformed by metagenomic next‐generation sequencing (mNGS), an unbiased approach that detects bacteria, viruses, fungi, and parasites in a single assay. By sequencing ...

Sepsis remains one of the most complex and lethal syndromes in pediatric critical care, driven by dysregulated and heterogeneous host responses to infection. Despite decades of biomarker research, few biomarkers have bee...

Background: Melanoma represents a highly aggressive and metastatic form of malignant skin cancer. that remains challenging to treat clinically. Tumor cells often reprogram nicotinamide adenine dinucleotide (NAD⁺) metab...

Abstract Objective: The present study has the following objectives: 1) identify differentially expressed proteins and pathways in blood samples of bipolar disorder (BD) compared to healthy controls (HC) by employing hig...

The incidence of lung cancer in Indonesia by 2020 has reached 34.783 cases. Melinjo contains ursolic acid and polydatin, which can suppress cell proliferation and induce cell apoptosis, respectively. This study aims to d...

Leishmaniasis is a public health disease that requires the development of more effective treatments and the identification of novel molecular targets. Since blocking the PI3K/AKT pathway has been successfully studied as ...

Pseudomonas aeruginosa is a highly pathogenic Gram-negative microorganism associated with high mortality levels in burned or immunosuppressed patients or individuals affected by cystic fibrosis. Studies support a coloniz...

Abstract Background Guidelines‐driven screening protocols for early cancer detection in dogs are lacking, and cancer often is detected at advanced stages. Hypothesis/Objectives To examine how cancer typically is detect...

Tear viscosity is a critical property affecting tear distribution and ocular surface stability. While not widely established as a primary diagnostic marker, deviations from normal viscosity can impact ocular health, pote...