Buscar recursos académicos

Abstract Background Head and neck squamous cell carcinoma (HNSCC) is a prevalent and aggressive malignancy with limited prognostic markers. Ubiquitin-specific peptidase 33 (USP33) has emerged as a potential modulator of ...

Objective Endometriosis (EMs) is a chronic gynaecological condition characterised by the ectopic growth of endometrial tissue; however, its molecular mechanisms remain insufficiently understood. Ferroptosis, an iron-depe...

IntroductionIntestinal ischemia-reperfusion (I/R) injury, a common and severe clinical condition with high morbidity and mortality, burdens healthcare systems. Our previous investigations established that a nano-delivery...

ObjectiveUsing different enrichment methods to isolation Vibrio parahaemolyticus （VP） from environmental samples for support source tracing of a congregative foodborne disease outbreak.MethodsCollected the epidemiolo...

BackgroundThe dengue virus (DENV) can cause various clinical syndromes and organ damage, known as dengue fever, with the probability of developing severe dengue. However, the underlying mechanisms of host response agains...

Aims This study aimed to explore the prognostic and immune-related associations of adiponectin-related genes in melanoma.Methods Single nucleotide polymorphism (SNP) and transcriptomic data from the Integrative Epidemiol...

ABSTRACT Background and Aims Familial Mediterranean Fever (FMF) is a monogenic autoinflammatory disease caused by mutations in the MEFV gene, resulting in recurrent inflammatory episodes and a risk of developing amyloido...

Objective: To investigate the role of integrin beta-1 (Itgb1) in radiation-induced tissue injury and elucidate its underlying molecular mechanisms. Methods: Differentially expressed genes associated with radiation injury...

Abstract Theileriosis, a tick-borne disease caused by apicomplexan parasites of the genus Theileria, poses a major constraint to livestock productivity worldwide. Existing chemotherapeutics are increasingly limited by ho...

FtsZ is a tubulin homolog in bacteria. It forms a Z-ring to recruit other proteins in the process of cell division through its GTPase activity. Amino acid sequence of FtsZ was obtained from uniprot database and used for ...

Abstract Deoxynivalenol (DON), a prevalent Fusarium mycotoxin, poses a significant threat to intestinal health in piglets. This study established a deoxynivalenol (DON) intoxication model in piglets, revealing compromise...

ObjectiveTo evaluate the antimicrobial resistance characteristics and molecular epidemiological features of Escherichia coli in retail whole chickens in Beijing， including resistance rates， resistance profiles， ser...

Abstract Bacteriophages constitute a major component of the human gut virome, playing very important roles in shaping of the structure and function of the gut microbiota. Moreover, bacteriophages interact with the human ...

Abstract Background Antibiotic‐responsive enteropathy (ARE) is diagnosed by excluding other causes of diarrhea and when there is a short‐term response to administration of antibiotics. Objectives To characterize the ...

ObjectiveTo identify the suspicious food， etiologic agent， and risk factors of a foodborne disease outbreak in a middle school in Nanjing， and to examine issues identified during the investigation， thereby provid...

Background: Liver hepatocellular carcinoma is a highly prevalent and lethal malignancy. The orphan cytokine receptor-like factor 3, although evolutionarily conserved and implicated in hematopoiesis and neuroprotection, r...

Abstract The MYB transcription factor family is one of the largest and most functionally diverse groups of transcription factors in angiosperms. Members of this family participate in a wide array of biological processes,...

ABSTRACT Jackfruit (Artocarpus heterophyllus) thrives in subtropical and tropical areas but is vulnerable to winter cold stress. The myeloblastosis (MYB) transcription factor family plays an important role in plant biolo...

Abstract Background Carotid atherosclerosis is a kind of systemic atherosclerosis in the carotid arteries. It remains one of the leading causes of ischemic stroke. However, the efficiency of treatment is insufficient. Th...

Hereditary Hearing Loss (HHL) is a common trait affecting 1 in 2000 new born children. The presence of over 100 different genes involved in HHL, lead us to go on board with Whole Exome Sequencing (WES) in order to search...

ObjectiveTraceability and pathogenetic analysis of two suspected homologous （S. aureus） food poisoning cases.MethodsWe conducted initial screening of pathogens in collected samples of suspected contaminated food， a...

Abstract Background I Kappa B Kinase Interacting Protein (IKBIP) has been reported to promote tumor progression in diverse cancers. however, the role of IKBIP in hepatocellular carcinoma (HCC) has remained unclear. Metho...

Abstract The role of Bisphenol A (BPA) in endometrial cancer (EC) remains uncertain. In this study, we integrated toxicological prediction, network toxicology, gene expression profiling, survival analysis, and molecular ...

Abstract Objective This study aimed to investigate the effect of miRNAs differentially expressed in serum exosomes on endothelial cells after myocardial infarction. Design & methods Specific pathogen-free male Sprague–...