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Abstract The in-situ upcycling of decentralized methane and nitrogen gas (N2)-derived ammonia via methanotrophic bacteria is highly attractive. However, the toxic intermediate generated from ammonia oxidation significant...

IntroductionThe limited availability of suitable scaffolds for three-dimensional (3D) cell culture has driven the development of new biomaterials. In this study, we developed a porcine fibrin matrix gel (PFMG) derived en...

ABSTRACT Spinal cord injury (SCI), which is a severe complication of spinal fractures, often causes the dysfunction of the spinal cord and results in sensory and motor abnormalities. Current clinical treatments—includi...

Background. Viral infections remain a major global health threat despite advances in vaccines and antiviral drugs due to the rapid emergence of resistance and new viral pathogens. Antiviral peptides (AVPs) are promising ...

Horticultural growing media (GM) are increasingly expected to provide reliable biological functions, yet microbial inoculants and native microbiota often perform inconsistently. We argue that this variability arises beca...

Abstract Background Chinese hamster ovary (CHO) cells are pivotal in biopharmaceutical production, yet balancing high recombinant protein yield with cell survival remains challenging. While previous studies have targeted...

Abstract Biological production of adipic acid, a crucial building block in nylon and polymer manufacturing, from renewable feedstocks has attracted attention as a sustainable alternative to the traditional petrochemical ...

Structural health monitoring (SHM) has become a central tool for managing civil infrastructure. In modern SHM, the physical structure and the SHM system together form a coupled cyber-physical system. Due to the networked...

Abstract Many sulfated polysaccharides (SPSs) possess useful physicochemical properties and biological activities and are widely used in industry. Currently, major SPSs are derived from livestock and marine organisms. To...

Abstract Echo State Networks are recurrent neural networks that leverage a random reservoir’s dynamics, training only a simple readout layer. This approach is computationally efficient but limits network performance. B...

The invasive brain-computer interface (BCI) is a method that involves implanting microelectrodes into brain tissue to collect neural electrical signals. The signals obtained through this method are often of high precisio...

Abstract Chimeric antigen receptor (CAR) T cell therapies have achieved clinical success in autologous treatment of hematological malignancies. However, their broader application remains limited. Beyond the biological ch...

This review discusses organic semiconductors interfaced with biomolecular systems, focusing on the construction of material systems through biochemical pathways for device nanoarchitectonics. The initial section highligh...

Abstract Background Long COVID is an infection-associated chronic condition with uncertain evolution, leading to ambiguity in case definitions and various hypotheses about its pathophysiology. Despite this diversity, cau...

Jiahui Zhang,1– 3,* Junran Tong,1– 3,* Yang Sun,4,* Jinpeng Sun,1– 3 Ran Gao,1– 3 Di Sun,5 Xiaopeng Guo,6 Yumiao Wei1– 3 1Department of Cardiology, Union Hospital, Tongji Medical College...

Abstract Background Gastric cancer (GC) remains a major global health challenge with persistently poor survival rates, largely attributable to late-stage diagnosis and the inherent limitations of conventional imaging mod...

Thermoset and fiber-reinforced composites (FRCs) are widely adopted for their exceptional mechanical strength, thermal resistance, and chemical stability that have demonstrated versatile applications across aerospace, au...

Abstract Background The ability to guide stem cells toward the bone-forming lineage is a fundamental aspect of regenerative medicine. Conventional protocols for osteogenic differentiation of mesenchymal stem cells typica...

Synthetic biology is emerging as a frontier interdisciplinary discipline that is increasingly regarded as a key driver of sustainable innovation in advanced materials. By leveraging the design-build-test-learn (DBTL) cyc...

Abstract The search for high-efficiency antimicrobial nanomaterials has intensified due to the escalating threat of antibiotic resistance. In this study, titanium dioxide nanoparticles (TiO2 NPs) were synthesized using a...

Brain–computer interfaces (BCIs) based on motor imagery (MI) provide a transformative direct communication pathway for patients with severe motor disabilities. However, the high inter-subject variability and non-statio...

This study investigates the complementary modulation of chitosan/keratin hydrogels through the combined use of hexamethylene diisocyanate (HDI) and Pluronic F-68, aiming to tailor mechanical stability, porosity, and biol...

Spiking neural networks (SNNs) offer a biologically inspired, energy-efficient alternative to conventional artificial neural networks (ANNs). However, deep SNNs struggle to process complex EEG signals because their spike...

Abstract Bone defects present significant challenges in clinical practice due to the limitations of traditional treatments. Compared to traditional cell therapies, exosome-based therapies have emerged as a promising alte...