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Abstract Background Reliable identification of protein‑protein interactions (PPIs) is crucial for deciphering cellular functional networks. Current research models still face limitations in aligning heterogeneous featu...

Abstract Background Protein-protein interaction (PPI) network-based protein function prediction algorithms, which use the guilt-by-association principle, are widely applied in medical and human domains, but they are comp...

This study involves the theoretical calculation of binding energy (the free energy ΔG°) of eleven of polycyclic aromatic hydrocarbons (PAHs) compounds with catechol 1,2-dioxygenase enzyme from the gram-positive Rhodoco...

Heavy metal pollution has become a major global concern due to its serious threats to ecosystem stability and public health. Although significant progress has been achieved in physical, chemical, and biological remediati...

Abstract This study reports the green biosynthesis of bioactive selenium nanoparticles using Catharanthus roseus extract as a reducing and stabilizing agent. Liquid chromatography–electrospray ionization tandem mass sp...

Shellfish peptides, recognized as a valuable source of marine bioactive compounds, have garnered increasing attention because of their diverse physiological functions and potential functional food, pharmaceutical, and co...

Abstract Quantum-mechanical simulations provide the most fundamental description of matter, yet their computational cost commonly limits applications to systems containing at most thousands of atoms. Here, we present an ...

Abstract Background Lavandula stoechas L., commonly known as lavender, has been traditionally used in various therapeutic applications, including as a smoking cessation aid. The aim of this study was to investigate the a...

The role of natural enemy diversity in biological pest control has been debated in many studies, and understanding how interactions amongst predators and parasitoids affect herbivore populations is crucial for pest manag...

Bacteria of the genus Bradyrhizobium are able to establish a symbiotic relationship with peanut (Arachis hypogaea) root cells and to fix atmospheric nitrogen by converting it to nitrogenous compounds. Quorum sensing (QS)...

Galectins are a family of evolutionarily conserved animal lectins with pleiotropic functions and widespread distribution. Fifteen members have been identified in a wide variety of cells and tissues. Through recognition o...

Background The long-term biological effects of low-level exposure to artificial sweeteners remain debated. We integrated computational toxicology and Mendelian randomization (MR) to explore potential biological responses...

It is clear that malaria, a disease caused by Plasmodium spp., has burdened humans throughout our evolutionary paths and remains one of the deadliest maladies to date. Yet, in sharp contrast to the consequence, the human...

IntroductionThe global prevalence of non-tuberculous mycobacterial pulmonary disease (NTM-PD) is increasing. Individuals with NTM-PD frequently develop chronic pulmonary aspergillosis, which is associated with poor clini...

Nonlinear optics, when combined with microscopy, is known to provide advantages including novel contrast, deep tissue observation, and minimal invasiveness. In addition, special nonlinearities, such as switch on/off and ...

Aims: Galectin-3 (Gal-3) and carbohydrate antigen 125 (CA125) have emerged as robust prognostic biomarkers in heart failure. Experimental data have also suggested a potential molecular interaction between CA125 and Gal-3...

The rhizosphere is one of the most dynamic biological environments on Earth. Within this narrow zone surrounding plant roots, plants interact constantly with diverse communities of microorganisms including bacteria, fung...

Abstract A novel Schiff base (L) was synthesized via the condensation of folic acid with salicylaldehyde, and its copper (II) complex (Cu–L complex) was subsequently prepared, exhibiting notable biological activity. Co...

Mathematics and computer science play a pivotal role in modern biology. Dynamical models based on differential equations are particularly adapted to describe dynamic behaviors of many biological processes. However, tradi...

Abstract Toxoplasma gondii, Plasmodium spp., and Leishmania spp. collectively infect billions and cause millions of deaths worldwide. In French Guiana, the geographical coexistence of malaria, acute toxoplasmosis, and cu...

Elevated blood pressure is commonly linked to diminished pain perception, a phenomenon known as blood pressure-related hypoalgesia. Interoception, the ability to perceive and interpret internal bodily signals, has been p...

Chronic pain affects hundreds of millions worldwide, yet current treatments—from NSAIDs to opioids—fall short and bring unwanted side effects. Neuroinflammation drives bidirectional glial-neuronal communication, a co...

Patagonia offers several examples of local adaptation in the exotic rainbow trout Oncorhynchus mykiss. Specifically, the Valcheta Stream, characterized by hot spring headwaters and temperate lower reaches, was initially ...

Neltuma spp. (previously known as Prosopis spp.) are vital for ecological restoration and sustainable forestry in arid and semiarid environments. Although extensively studied, nursery techniques are still inconsistently ...