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Glioblastoma is the most common and aggressive primary brain tumor in adults that fails to meet survival endpoint criteria in current immunotherapy Phase III clinical trials. As a small subset of immunotherapy-responsive...

INTRODUCTION: A growing body of evidence suggests that bipolar disorder (BD) is a progressive disease according to clinical, biochemical and neuroimaging findings. This study reviewed the literature on the relationship b...

Materias / palabras clave: neuropsychiatric disorders, diagnostic biomarkers, prognostic biomarkers, predictive biomarkers, monitoring biomarkers, neuroimaging biomarkers; Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsy...

Abstract Background Repetitive transcranial magnetic stimulation (rTMS) is an efficacious therapy for treatment-resistant depression (TRD) and is thought to drive neuroplastic changes in affective networks. However, up t...

Abstract Ovarian cancer is one of the deadliest gynecological malignancies, mainly because of its silent development and the lack of effective conventional methods for diagnosis. Because of their extraordinary stabilit...

Urban air pollution is a serious environmental problem in developing countries worldwide, and health is a pressing issue in the megacities in Latin America. Buenos Aires is a megacity with an estimated moderate Air Quali...

Abstract Background Differentiating benign from canine malignant mammary tumors requires invasive surgical biopsy. Circulating microRNAs (miRNA) may represent promising minimally invasive cancer biomarkers in people and ...

BackgroundSarcopenia elevates risks of falls, hospitalization, and mortality in older adults. Despite protein’s importance for muscle maintenance, evidence on its overall and source-specific role in sarcopenia developm...

ABSTRACT Background and Aims Qigong is an ancient Chinese psychosomatic system with a fascinating holistic approach to health, which exerts remarkable physical and mental benefits. Nevertheless, this method has been scar...

Weiming Hao,1 Ruigao Song,1 Huimin Lv,1 Chunying Song2 1Reproductive Medicine Center, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiy...

Abstract Backgrounds Acute primary angle-closure glaucoma (APACG) and chronic primary angle-closure glaucoma (CPACG) exhibit distinct clinical features, yet the molecular mechanisms underlying their differing progression...

Abstract Breast cancer is still the most significant contributor to morbidity and mortality among women in China. Despite advances in imaging and molecular testing, few reliable biomarkers exist for early detection and d...

ObjectiveThis study aimed to identify core inflammatory biomarkers through machine learning approaches and develop an accessible online risk calculator to predict pulmonary consolidation in children with Chlamydia pneumo...

Abstract High-throughput omics technologies have transformed our understanding of female reproductive biology, revealing molecular interactions governing oocyte maturation, ovarian reserve, endometrial receptivity, and e...

Carotid artery stenting (CAS) has emerged as an effective alternative to carotid endarterectomy for treating carotid artery stenosis, particularly in high-risk surgical patients. However, in-stent restenosis (ISR) remain...

IntroductionAnti-amyloid antibodies have the potential to become the standard of care in Alzheimer’s Disease (AD) and large datasets from clinical trials allow the testing of predictive models on fluid biomarkers and f...

Autosomal dominant polycystic kidney disease (ADPKD), characterized by the development of multiple cysts in the kidneys and other organs, is the most common hereditary renal disorder and the fourth leading cause of end-s...

Background Depression in adolescents is recognised as a global public health concern, but little is known about the trajectory of its clinical symptoms and pathogenesis. Understanding the nature of adolescents with depre...

Abstract Background Autoantibody biomarkers are valuable tools used to diagnose and manage autoimmune diseases in dogs. However, prior publications have raised concerns over a lack of standardization and sufficient valid...

OBJECTIVE: Cardiovascular diseases are prevalent in asymptomatic chronic hemodialysis patients. New cardiac biomarkers are required for early diagnosis of cardiovascular diseases. In our study, we aimed to investigate as...

ABSTRACT Background and Aims Chronic inflammation contributes to various chronic diseases, emphasizing the need for reliable biomarkers for early detection and understanding its causes. Measuring chronic inflammation pos...

Avaliou-se o uso de brânquias, fígado e rins como biomarcadores histológicos em ensaio de toxicidade crônica com o herbicida Roundup® em piauçu (Leporinus. macrocephalus). Para tanto, os animais foram expostos a 1,...

Abstract Background Blood eosinophil count is an accepted biomarker for type 2 inflammation in COPD. However, the majority of COPD patients are characterized by non-type 2 inflammation. We aimed to test readily obtainabl...

To characterize peripheral blood natural killer (NK) cells phenotypes by flow cytometry as potential biomarker of liver fibrosis in human immunodeficiency virus (HIV)/hepatitis C virus (HCV) coinfected patients. Samples ...