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Materias / palabras clave: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the genitourinary system. Urology; Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens

Materias / palabras clave: bladder cancer, urothelial carcinoma, upper urinary tract cancers; Medicine: Internal medicine: Specialties of internal medicine: Diseases of the genitourinary system. Urology; Medicine: Internal medicine: Neoplasms. Tum...

Abstract TP53 is frequently mutated in bladder cancer and is associated with aggressive disease, yet actionable strategies that also improve responses to immune checkpoint blockade remain limited. Here we show that APR-2...

Abstract Introduction Bladder cancer (BLCA) is a malignant tumour that occurs on the mucosa of the bladder. It accounts for the first place in the incidence of genitourinary tumours in China. BLCA is characterized by hig...

Tire and Road Wear Particles (TRWP) are pervasive environmental contaminants, yet the molecular mechanisms linking their toxic derivative, 6PPD-quinone (6PPD-Q), to bladder cancer (BLCA) progression remain obscure. This ...

Bladder cancer is a highly malignant tumor with limited treatment options. Although adoptive cell therapy has shown promise in oncology, its efficacy is often constrained by poor intrinsic antitumor activity and a highly...

Aberrant DNA methylation observed in cancer can provide survival benefits to cells by silencing genes essential for anti-tumor activity. DNA-demethylating agents such as Decitabine (DAC)/Azacitidine (AZA) activate otherw...

Abstract N6-Methyladenosine (m6A) is the most abundant internal modification of eukaryotic mRNAs and regulates target transcripts throughout the mRNA life cycle. Although changes in m6A have been reported in human cancer...

Materias / palabras clave: Bladder; Cancer; Treatment; Vejiga; Cáncer; Tratamiento

Materias / palabras clave: Cáncer; Urología; Riesgo; Bladder; Cancer; Urology; Spain; Urologia

Associations between periodontal disease (PD) and cancers risk have been described previously, but the evidence remains inconclusive. This study aimed to investigate the association between PD and specific cancers throug...

Background and Purpose: Anatomical variations during prostate radiotherapy can cause discrepancies between planned and delivered doses, which may become more pronounced in (ultra-)hypofractionated regimens. However, a st...

The interest in transition metal complexes as antitumor agents started in the 1960s with the serendipitous dis- covery of cisplatin. This drug was appr ov ed by the US FDA in the 1970s for its use as a chemotherapeutic a...

Purpose: To evaluate the impact of intra- and interfractional motion on dose distribution and clinical outcome in prostate magnetic resonance (MR)-guided adaptive radiotherapy. Methods: Seventy-six patients were treated ...