Buscar recursos académicos

Living organisms anticipate the seasons by tracking the proportion of light and darkness hours within a day—photoperiod. The limits of photoperiod measurement can be investigated in the subterranean rodents tuco-tucos ...

En este trabajo de Tesis se demostró, por primera vez, que la síntesis retiniana de prostaglandinas E2 y F2? en el hámster dorado varía circadianamente aún en condiciones de oscuridad constante y está regulada por ...

Circadian rhythms are essential for maintaining intervertebral disc (IDD) homeostasis and regulate cellular metabolism, mechanical responses, and therapeutic efficacy. Core clock genes, especially CLOCK and BMAL1, have c...

Abstract Background Circadian rhythms are endogenous, transcription-translation feedback loops that align cellular activities with the 24-h light–dark cycle. Stem-cell populations across tissues exhibit circadian oscil...

Circadian clocks coordinate time-of-day-specific metabolic and physiological processes to maximize organismal performance and fitness. In addition to light and temperature, which are regarded as strong zeitgebers for cir...

Abstract The mechanisms by which core clock components are spatially organized to ensure robust oscillations in mammals remain unclear. Here, we identify the positive limb factor BMAL1 as a phase-separating protein that ...

BackgroundWe have developed a mouse model of Parenteral Nutrition Associated Cholestasis (PNAC) in which combining intestinal inflammation and PN infusion results in cholestasis, hepatic macrophage activation, and transc...

Abstract The past 25 years have seen remarkable progress in plant circadian biology. This perspective highlights major advances in our understanding of the oscillator network, the processes it regulates, and circadian va...

The temporal dynamics in biological systems displays a wide range of behaviors, from periodic oscillations, as in rhythms, bursts, long-range (fractal) correlations, chaotic dynamics up to brown and white noise. Herein, ...

Objectives: An association, responsible for affecting circadian rhythms and sleep homeostasis, between PER3 gene variable number tandem repeat (VNTR) and sleep times has been described in humans. The aim of this study wa...

Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common chronic liver disease around the world, with at least 40% global prevalence. Although genetic susceptibility contributes to disease risk...

Non-infectious uveitis encompasses a diverse array of autoimmune ocular disorders marked by the breakdown of immune tolerance and recurrent inflammatory episodes. Regulatory T cells (Tregs) are integral to the maintenanc...

Fil: Goya, María Eugenia. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología. Laboratorio de Cronobiología; Argentina. Los ritmos circadianos están basados en relojes endógenos que les permiten a ...

Fil: Migliori, María Laura. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología. Laboratorio de Cronobiología; Argentina. Los ritmos circadianos (del latín circa y dies: cerca de 24 horas) tienen un...

Materias / palabras clave: circadian and sleep physiology, sleep habits and health, sleep–wake behavior and the 24-h society/life-style, computational modelling in the sleep and circadian fields; Medicine

Materias / palabras clave: circadian rhythm, biological clock, chronobiology, biological timing, molecular clock, photoperiodism; Science: Biology (General)

Materias / palabras clave: circadian biology, sleep, biological rhythms, chronobiology, circadian clock, biological timekeeping; Science: Biology (General); Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry