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Abstract Background Apoptosis is a continuous process throughout follicular development and plays a critical role in normal ovarian physiology. Although the key apoptotic molecule-encoding genes have been well characteri...

Coronary artery disease (CAD) remains a leading cause of morbidity and mortality worldwide. Over the past three decades, percutaneous coronary intervention (PCI) has evolved from a anatomical revascularization technique ...

Anatomy and anatomy and physiology (A&P) courses are crucial to prepare quality health care professionals. Considerable research has focused on graduate-level anatomy education, with fewer studies examining course conten...

Function diagrams focus on physiological concepts rather than associated structures and can serve as elaboration tools and mnemonic aids. A function diagram prototype of the gastrointestinal system was recently described...

Anatomical education presents ongoing challenges in helping students master complex content while integrating it with clinical relevance. Neuroanatomy is particularly difficult due to its intricacy and abstract nature. T...

Flow cytometry has become an important tool in the fields of veterinary, medicine, and biological sciences in general. However, in the introductory and even in advanced university degree courses, students do not have man...

Abstract Clinicians often view exposure to supplementary oxygen in preterm infants as a simple reciprocal trade‐off between mortality and the risk of vision‐threatening retinopathy, but this perspective oversimplifie...

Abstract Background Preterm low birth weight (PLBW) is a major global contributor to neonatal morbidity and mortality. This study aims to develop and evaluate a novel artificial neural network (ANN) based predictive mode...

Materias / palabras clave: Science: Physiology; Medicine: Internal medicine: Specialties of internal medicine: Diseases of the endocrine glands. Clinical endocrinology

Abstract Chronic obstructive pulmonary disease (COPD) is an inflammatory lung disease caused by inhalation of noxious particles, most commonly cigarette smoking. The consequent changes in airways, lung parenchyma and pul...

Mehmet Zafer Aydın,1 Can Baba Arin,2 Mehmet Kamil Teber,1 Zülfiye Kuzu,1 Mustafa Gök,1 Ishak Ahmed Abdi3 1Department of Cardiology, Kayseri City Training and Research Hospital, Kayseri, Turkey; 2Department o...

Drug discovery research faces significant challenges, with around 90 % of candidate drugs failing in clinical trials. Traditional animal models do not always accurately reflect human physiology and pathology, leading to ...

Primary aldosteronism (PA) is the most common cause of secondary hypertension in many populations worldwide. Although hypertension with recurrent hypokalemia from renal potassium wasting and simultaneously elevated plasm...

Abstract DIS3, a key nuclear RNA-degrading enzyme, is essential for immunoglobulin class switch recombination (CSR), promoting activation-induced cytidine deaminase (AID) activity on both DNA strands to induce double-str...

Abstract The heart-brain axis is a significant contributor to morbidity and mortality following ischemic injury. Pathological and psychological changes in the heart can lead to anxiety, cognitive impairment, and brain in...

Background. The human gastrointestinal tract contains a large community of microorganisms, known as the gut microbiota. Their metabolic and immunological functions influence host physiology. Disruption of this community,...

Abstract Background Proteins and RNA circulate in plasma and can offer insights into human physiology. Yet, despite their clinical importance, direct comparisons between these analytes remain unexplored. Methods: Here, w...

Abstract Background Oral frailty is a significant risk factor for systemic frailty and poor health outcomes in older adults. While oral health care interventions may mitigate this decline, the evidence remains fragmented...

BackgroundEvidence suggests that 41% of ICU patients acquired postextubation dysphagia, substantially increasing the risk of aspiration and malnutrition. Studies on its prevalence and risk factors showed considerable var...

Abstract To evaluate the incidence of bleeding and thrombotic events in children with congenital or acquired heart disease (CAHD) receiving direct oral anticoagulants by rivaroxaban, and identify associated covariates. T...

Objective: Ambulatory blood pressure (BP) monitoring is confronted with different clinical patterns due to diurnal changes. Rise of BP at night is known as reverse dipper, whereas it is expected to decrease at night phys...

ABSTRACT Background and Aims Depression is a common and chronic mental health problem, and the diagnosis and management of depression require continuous monitoring. In this review study, sensor‐based digital tools for ...

Abstract Background Triage at major incidents has traditionally relied on assessing physiology, and in the UK, this role has usually been performed by healthcare responders. However, recent major incidents have shown tha...

BackgroundType 2 diabetes (T2D) is a heterogeneous disease for which (1) disease-causing pathways are incompletely understood and (2) subclassification may improve patient management. Unlike other biomarkers, germline ge...