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This study aimed to investigate the clinical significance of bee venom pharmacopuncture in patients with Bell’s palsy by synthesizing evidence from several comparative clinical studies. A narrative review was conduct...

ABSTRACT Background and Aims Pulmonary embolism is a cardiovascular disease associated with significant morbidity and mortality. There is a paucity of literature regarding this condition from the Ghanaian perspective. Th...

ABSTRACT: Objectives: To evaluate and synthesise the current evidence on the efficacy of laser-activated irrigation in endodontics, with a focus on microbial reduction, postoperative outcomes, and its potential as an ad...

Leishmaniasis is a parasitic disease caused by hemoflagellates of the genus Leishmania and is transmitted to humans by the bite of infected phlebotomine sandflies. Depending on the Leishmania species, the disease has dif...

ObjectiveTo investigate the clinical features and serological characteristics of patients with primary Sjögren's syndrome (pSS) complicated with sensorimotor neuropathy (SMN), and to provide a reference for the clinical...

Abstract Background Studies describing the clinical progression of animals with reverse patent ductus arteriosus (PDA) are lacking. Objectives To describe the signalment, presenting signs, echocardiographic features, and...

Mitochondrial dysfunction can lead to the accumulation of fatty acids and excessive production of reactive oxygen species (ROS), ultimately resulting in impaired energy production. Carnitine is essential for transporting...

ABSTRACT Background Leonurine (LEO), a bioactive alkaloid derived from the Leonurus genus, exhibits diverse pharmacological activities including uterotonic, antioxidant, anti‐inflammatory, antiapoptotic, Antitumor, and...

The therapeutic efficacy of Mesenchymal Stromal Cells (MSCs) has been demonstrated in a multitude of pre-clinical studies and clinical trials, yet the translation of MSC therapies is limited by biological factors such as...

Medicarpin (MED) is an isoflavonoid compound derived from traditional Chinese medicine (TCM). Numerous preliminary experimental studies have shown that MED has significant pharmacological effects in the treatment of canc...

Background and purpose: Deviations in radiotherapy quality can significantly affect clinical trial outcomes, including overall survival. Radiotherapy quality assurance (RTQA) is a systematic process by which a RT plan is...

BackgroundDelivering accurate radiation doses in heterogeneous tissues is critical in radiotherapy, yet conventional algorithms often lose accuracy in complex scenarios. Monte Carlo (MC) simulation offers a high-fidelity...

Abstract Objective: Cushing’s syndrome, characterized by chronic hypercortisolism, is associated with various health risks, including psychiatric symptoms and cognitive impairments. This systematic review of case stud...

IntroductionLarge language models (LLMs) may support clinical reasoning, yet real-world outpatient studies integrating structured clinical data with chest radiographs (CXRs) remain limited. We compared three LLMs for pul...

Oropharyngeal infection has long been associated with cardiovascular disease (CVD), specifically valvular disease and endocarditis. However, the relationship between periodontal disease (PD), with associated infection an...

Abstract Background Autism spectrum disorder (ASD) is a complex neurodevelopmental condition with rising global prevalence. Current management strategies predominantly address behavioral symptoms rather than core neurobi...

Recent advances in Alzheimer’s disease research have reshaped how clinical trials are designed and interpreted, particularly through the use of targeted monoclonal antibodies, biomarker-guided enrollment, and novel dru...

Associations between periodontal disease (PD) and cancers risk have been described previously, but the evidence remains inconclusive. This study aimed to investigate the association between PD and specific cancers throug...

Abstract Background Acute liver failure (ALF) is a life-threatening syndrome characterized by rapid deterioration of liver function, resulting in high mortality and posing a substantial global health burden. Human embryo...

Introduction and aims: Early clinical exposure (ECE) integrates students into clinical settings during theoretical learning, aiming to foster professional development. This systematic review aims to comprehensively evalu...

BackgroundMind mapping has been widely used as an intervention in medical education of China’s standardized residents training (SRT) program. Our study aims to investigate the effectiveness of mind mapping compared wit...

Background: BPC-157 and GHK-Cu are synthetic peptides with potential in tissue repair, influencing molecular mechanisms in healing, angiogenesis and inflammation. Objective: This review synthesizes preclinical and cli...

Abstract Introduction Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remains a global public health concern. Anti-nucleocapsid (anti-N) serology is a key tool for identifying prior infection and supporting ...

BackgroundFibromyalgia affects 2%–8% of the global population with suboptimal treatment outcomes. Emerging evidence suggests histamine intolerance, mediated by diamine oxidase (DAO) deficiency, may contribute to fibrom...