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Summary 1. Here, I present a new, multifunctional phylogenetics package, phytools, for the R statistical computing environment. 2. The focus of the package is on methods for phylogenetic comparative biology; however, it ...

Materias / palabras clave: Science: Biology (General)

Materias / palabras clave: Science: Biology (General): Genetics

Introduction and aims: To evaluate the diagnostic and reasoning capabilities of 4 state-of-the-art large language models (LLMs) on the Korean Dental Licensing Examination (KDLE) and to assess their potential as education...

Abstract The nematode Ditylenchus destructor comprises multiple haplotypes with distinct host preferences, while the genetic basis remains unclear. We generate three genomes (Haplotypes A, B, and C) using hybrid assembly...

Abstract Background Enhancing nitrogen use efficiency (NUE) is essential for sustainable agriculture. Stress response pathways play a significant role in regulating NUE across various growth stages and organs. Therefore,...

Abstract Objective Medical education aims to prepare future physicians for high-quality patient care. This prospective study examines the perceptions of medical students and clinical teachers with regard to teaching in o...

Materias / palabras clave: Law: Law in general. Comparative and uniform law. Jurisprudence; Science: Biology (General): Ecology

Abstract Background Protein-protein interaction (PPI) network-based protein function prediction algorithms, which use the guilt-by-association principle, are widely applied in medical and human domains, but they are comp...

Regulatory science governing monoclonal antibody development has undergone a profound transformation over the past decade, shifting from empiricism-driven paradigms toward evidence-efficient, mechanism-based frameworks g...

Craniofacial morphogenesis is a highly coordinated developmental process governed by complex genetic and molecular interactions. Among these, the PAX family of transcription factors plays a pivotal role in the regulation...

MicroRNAs (miRNAs), a class of small non-coding RNAs, are key regulators of gene expression at post-transcriptional level and play essential roles in biological processes such as development. MiRNAs silence target mRNAs ...

Emmanuel Ifeanyi Obeagu1– 3 1Division of Haematology, Department of Biomedical and Laboratory Science, Africa University Mutare, Mutare, Zimbabwe; 2Department of Molecular Medicine and Haematology, School of Pathology,...

Human babesiosis caused by the intraerythrocytic apicomplexan Babesia microti is an expanding tick-borne zoonotic disease that may cause severe symptoms and death in elderly or immunocompromised individuals. In light of ...

Parasitic worms have significant medical, veterinary and economic importance. Numerous studies have therefore addressed various aspects of parasitic worms’ biology. In contrast, the ploidy of parasitic worms remains co...

Aging is characterized by measurable reductions in tissue repair, immune balance, and metabolic regulation. Increasing evidence suggests that these changes may arise, in part, from an insufficiency or altered quality of ...

Abstract Seed selection constitutes the initial and one of the most critical steps in agricultural productivity. The identification of high-quality seeds is a labor-intensive and costly process that requires considerable...

Royal jelly is a unique product of worker bees, namely the secret of their pharyngeal and maxillary glands. It is the main source of nutrients and biologically active substances for larvae and queens. Royal jelly include...

Abstract Background The use of biostimulants in agriculture has shown fabulous potential in combating climate change induced stresses such as drought. Improving agricultural productivity requires sustainable drought stre...

Abstract Background Endometriosis is a highly prevalent, hormone-driven chronic disease characterized by the growth of endometrial tissue outside the uterine cavity. Despite its impact, the mechanisms underlying the dise...

The article investigates the effects of exercise modalities on metabolic disturbances and the gut microbiome in women with metabolic syndrome The relevance of the study is determined by the rapidly increasing prevalence ...

Ganoderic acids (GAs), the major lanostane-type triterpenoids in Ganoderma lucidum (G. lucidum), possess diverse pharmacological activities but are produced at low levels, limiting their applications. Transcriptional reg...

Abstract Background Laccases (LACs) are multicopper oxidases that play vital roles in lignin polymerization, cell wall formation, and various stress responses in plants. Despite their importance, genome-wide investigatio...

Abstract We present HiChew, a novel chromatin conformation capture method combining efficient sticky-end ligation with post-PCR methylation-based enrichment. HiChew achieves approximately 50% valid pair ratios compared t...