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Transdifferentiated melanoma is a rare variant of melanoma characterized by phenotypic plasticity, loss of conventional melanocytic markers, and acquisition of features from other tissue lineages, often associated with a...

With the purpose of shedding light on some doubts in veterinary oncology, the present article intends to compare the results of histopathological and immunohistochemical examinations of unspecific round cell neoplasia, t...

Abstract Background Radiation therapy is commonly used as an adjunct to incomplete surgical excision in dogs with mast cell tumors (MCT), but the optimal dose and fractionation regimen have yet to be determined. Hypothes...

ABSTRACT This case report describes the outcome of treatment of dogs with advanced (deeply invasive) nasal planum squamous cell carcinomas with palliative or definitive radiation therapy. All dogs were diagnosed with nas...

Introduction Mucosal melanoma (MM) carries a high risk of postoperative relapse and poorer survival than cutaneous disease. Prospective data from China support adjuvant temozolomide–cisplatin (TMZ/DDP) in resected MM, ...

BackgroundAdjuvant immune checkpoint inhibitors (ICI) have improved survival in stage III cutaneous melanoma, yet many patients do not benefit. The tumor microenvironment is pivotal for durable responses; defining cellul...

HER2-low breast cancer, defined as immunohistochemistry (IHC) 1+ or 2+ with negative in situ hybridization (ISH), has emerged as a clinically relevant therapeutic subgroup. We report the case of a 40-year-old woman with ...

Materias / palabras clave: investigative dermatology, cutaneous biology, cutaneous oncology, innate and acquired immunology, pigmentation and melanocytes, clinical trials; Medicine: Dermatology

Materias / palabras clave: skin cancer, melanoma, non-melanoma skin cancer, cutaneous malignancies, skin cancer diagnosis, skin cancer treatment; Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens