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Abstract Parasitic diseases such as malaria, leishmaniasis, and schistosomiasis remain difficult to treat due to the pathogens’ complex life cycles, intracellular niches, and resistance to conventional therapies. Tradi...

The complex etiology and short-term positive effects of treatments for osteoarthritis (OA) remain a significant challenge globally. The lack of approved disease-modifying OA drugs (DMOADs) and the rapid clearance of intr...

Abstract Vaccines represent the most cost-effective and efficacious approach for preventing gastrointestinal infections, and adjuvants play a pivotal role in enhancing and modulating immune responses. In this article, ...

Xiaoyi Fu,1 Zijian Zhang,1 Qinyi Dong,1 Siying Li,2 Xinman Wang,2 Han Zhang,2 Jiahao Bai,2 Huiyan Han,2 Lei Shi,2 Kaili Zheng,2 Lili Liang2,3 1The Third Clinical College, Shanxi University of Chinese Medicine, Taiyuan, S...

Microbial siderophores are low-molecular-weight compounds with a strong affinity for ferric (FSe3+) ions. They play a pivotal role in plant-microbial interactions by enhancing iron bioavailability to plants, primarily th...

Researchers in pharmacy are paying increasingly close attention to nanogel-based multifunctional drug delivery systems, particularly hybrid nanogels and multicompartment nanogels because they can lead to the achievement ...

Background. Viral infections remain a major global health threat despite advances in vaccines and antiviral drugs due to the rapid emergence of resistance and new viral pathogens. Antiviral peptides (AVPs) are promising ...

Biologic therapeutics have transformed the treatment of chronic and life-threatening diseases, yet their clinical use depends almost entirely on parenteral administration. Oral delivery is the preferred route for patient...

OBJECTIVE: Automated insulin delivery (AID) systems represent the most advanced technology for managing insulin-dependent diabetes. This review compares three AID systems currently available in Poland. MATERIALS AND METH...

Abstract Background Access to surgical care in Low- and Middle-Income Countries (LMICs) such as Tanzania is extremely limited. Northern Tanzania is served by a single tertiary referral hospital, Kilimanjaro Christian Med...

Films based on biopolymers and loaded with antimicrobial agents are convenient pharmaceutical dosage forms for topical application. Inorganic carriers loaded with these agents lead to composite materials, which combined ...

Two kinds of functionalized nanostructured hybrid microspheres, based on the bridged silsesquioxane family, were synthesized by employing the sol-gel method via self-assembly of two different organic-inorganic bridged mo...

Invasive fungal infections remain a major cause of global morbidity and mortality, with resistance to conventional antifungal agents posing an increasing challenge. Ethosomal nanocarriers have gained attention as effecti...

Abstract The advancement of sustained-release drug delivery systems is profoundly reshaping the medicinal applications. This study highlights a novel approach to developing sustained-release esterase responsive drug deli...

The rising concern of antimicrobial resistance, coupled with the continually challenging management of complicated diseases such as cancer, has provided momentum toward precision molecular medicine. This review provides ...

Abstract Breast cancer remains one of the most prevalent malignant tumors affecting women worldwide and continues posing a major threat to global health. Current clinical treatments include surgery, chemotherapy, radioth...

Climate change is creating serious challenges for fisheries in coastal Nigeria. Fisheries extension workers, who support fishers with advice and training, must themselves be resilient to continue delivering services. Thi...

An Automatic Guided Vehicle (AGV) is an automated vehicle used to support the delivery of food and beverages in restaurant service systems, where manual methods still carry risks of delays and spillage. This study design...

Abstract Diabetes mellitus represents one of the most prevalent chronic diseases worldwide, posing serious challenges to global health and healthcare sustainability. Conventional therapeutic strategies often face limitat...

Cyclodextrins (CDs)are a family of biodegradable cyclic hydrocarbons composed of α-(1,4)linked glucopyranose subunits, the more common containing 6, 7 or 8 glucose units are named α, β and γ-cyclodextrins respectivel...

Abstract Background Tuberculosis remains a major public health challenge in Somalia, where a fragile health system and reliance on private providers complicate care. Although Public-Private Partnerships are globally reco...

The design of novel delivery systems to treat vaginal fungalinfections is a topic of high interest. Chitosan, being itselfantimicrobial and having good mucoadhesive properties, is an excellentcandidate as a delivery matr...

Tobacco harm reduction (THR) using represents a pragmatic and realistic strategy, to which electronic nicotine delivery systems (ENDS) misperceptions act as a barrier. This paper explores ENDS misperceptions, especially ...

Artificial pancreas (AP) algorithms can be divided into single-hormone (SH) and dual-hormone (DH). SH algorithms regulate glycemia using insulin as their control input. On the other hand, DH algorithms also use glucagon ...