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The design of novel delivery systems to treat vaginal fungalinfections is a topic of high interest. Chitosan, being itselfantimicrobial and having good mucoadhesive properties, is an excellentcandidate as a delivery matr...

Materias / palabras clave: Aeronautical Vehicles; Space Vehicles; Management and Operations

Abstract Background Nanodelivery represents a promising strategy to enhance pesticide efficacy while reducing associated environmental risks. Mesoporous silica nanospheres (MSNs) can serve as effective nanocarriers but i...

ABSTRACT Selective recognition of cancer‐associated proteins (CAPs) by antibodies, followed by their delivery into the intracellular organelle, the lysosome, results in targeted degradation of CAPs and suppresses the g...

This study focuses on the development and optimization of a self-emulsifying drug delivery system (SEDDS) for Nevirapine, a BCS Class II non-nucleoside reverse transcriptase inhibitor (NNRTI) used in HIV therapy. Our obj...

Abstract Efficient and timely transportation of blood samples across medical centers is critically important, particularly in countries where traffic congestion significantly delays road-based delivery. The operational r...

Background: The growth of a topical vehicle microemulsions has been more enhanced compared to the normal skin applications such as creams, gels among others. These micro-structured vehicles showed enhanced solubilization...

Targeted delivery of drugs to tumor cells, which circumvent resistance mechanisms and induce cell killing, is a lingering challenge that requires innovative solutions. Here, we provide two bioengineered strategies in whi...

Amid escalating global climate concerns, the reliance of the transportation sector on high-carbon fossil fuels urgently demands sustainable alternatives. Hydrogen has emerged as a potent solution because of its zero-emis...

Ground handling delays at major airports pose significant challenges, impacting operational efficiency, airline schedules, and passenger satisfaction. This study explores the root causes of these delays, including resour...

Determining the performance characteristics of off the shelf pulsed plasma thrusters to enhance the life time of low earth orbiting platforms was investigated theoretically. Pulsed plasma thruster analysis was accomplish...

Efficiency in higher education has increasingly come under scrutiny as student debt levels continue to increase and the quantification of the value provided to students by colleges remains elusive. Collegiate flight trai...

Institutions of higher learning are offering varying course modalities to accommodate the changing needs of students. Notably, institutions of higher learning are offering an increasing number of compressed courses to me...

The Federal Aviation Administration (FAA) has put forth a set of regulations (Part 107) that govern small unmanned aerial system (sUAS) operations. These regulations restrict unmanned aircraft (UA) from flying over peopl...

Vehicles and enhancers effect on in vitro probenecid permeation through dermatomed abdominal pig skin was investigated. The permeability of different probenecid percentages dispersed in vehicles as vaseline, carbopol/e...

The objective of this work was to investigate feasibility of transdermal delivery of loratadine. Effect of pH, vehicles and chemical enhancers on the skin permeation of loratadine was studied in vitro, using rat abdomina...

A self-emulsifying drug delivery system (SEDDS) of a poorly water soluble drug, irbesartan (IRB), was designed. The aim was to improve the solubility as well as dissolution rates of IRB. Solubility of IRB in different ...

Hydroquinone (HQ) is a drug reported to possess manifold biological activities. HQ is highly unstable into various topical vehicles, presenting low topical bioavailability and a relevant level of toxicity. The Pluronic®...

Las microemulsiones son mezclas isotrópicas, estables, claras, constituidas por una fase oleosa, una acuosa y uno o más anfifílicos. Despiertan interés a nivel farmacéutico debido a varias ventajas que ofrecen: ca...

Materias / palabras clave: biofabrication, delivery vehicles, tissue engineering, regenerative medicine, cellular agriculture, in vitro models; Medicine: Medicine (General): Medical technology