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The increasing complexity of pharmaceutical management in pharmacies demands efficient systems to streamline drug classification and inventory control. As pharmacies handle a diverse range of formulations, including tabl...

This study focuses on the development and optimization of a self-emulsifying drug delivery system (SEDDS) for Nevirapine, a BCS Class II non-nucleoside reverse transcriptase inhibitor (NNRTI) used in HIV therapy. Our obj...

Aim and Objective: The study aimed to manufacture Bucco-adhesive tablets of Risperidone and characterize the effectiveness of the drug by incorporating it into the mucoadhesive drug delivery system. The sustained release...

Background: The growth of a topical vehicle microemulsions has been more enhanced compared to the normal skin applications such as creams, gels among others. These micro-structured vehicles showed enhanced solubilization...

Objective: This study was aimed at the formation and evaluation of the mucoadhesive gastro-retentive tablet of domperidone to overcome the drawbacks related to the oral administration of drugs. These gastro retentive for...

Objective: Lidocaine needs to be administered frequently as it has poor oral bioavailability and it lacks prolong duration of action thus the study was aimed at to devise, develop, and analyze a matrix system transdermal...

Objective: Development & Optimization of Ofloxacin Floating tablets to enhance gastric retention time. Sustained release effect of formulation will reduce the dosing frequency for UTIs and prolonged local effect will ben...

Pharmaceutical technology has increasingly integrated artificial intelligence (AI) in recent years. This technology offers significant benefits, including saving time and money while enhancing the understanding of the re...

ABSTRACT Background and Aims De novo drug design is the process of generating novel lead compounds that possess desirable pharmacological activities and optimal physicochemical properties for therapeutic development. In ...

Persistent cervical human papillomavirus (HPV) infection is the key biological event underlying high-grade squamous intraepithelial lesions, cervical cancer development, and recurrence risk. Botanical drugs and their bio...

ObjectivesSince its inception in 2017, China’s National Drug Price Negotiation (NDPN) has served as a crucial mechanism for the strategic procurement of innovative medicines, with pediatric medicines representing a key...

This study developed, optimized, and evaluated floating tablets containing Losartan potassium intended to provide prolonged gastric retention for hypertensive patients. HPMC K15M was found to effectively extend drug rele...

Developing aceclofenac hydrogel-based solid dispersions enclosed in two modified gelatin capsules for long-term medication delivery was the aim of this study. Eudragit L 100 and hydroxypropyl methylcellulose acetate succ...

Invasive fungal infections remain a major cause of global morbidity and mortality, with resistance to conventional antifungal agents posing an increasing challenge. Ethosomal nanocarriers have gained attention as effecti...

Trichinellosis is a zoonotic disease affecting people all over the world, for which there is no speedy and reliable treatment. Albendazole (ABZ), an inexpensive benzimidazole used in oral chemotherapy against helminthic...

Abstract Background Previous studies have indicated potential associations between some drugs and cancer risk, but the causal relationship with gastric cancer remains unclear. This study aimed to explore the causality be...

Objective To characterise temporal trends in antiretroviral therapy (ART) utilisation and forecast short-term changes in regimen distribution within a provincial HIV treatment programme.Design Population-level longitudin...

Background: Tianeptine sodium is an antidepressant drug possessing analgesic and anti-asthmatic property. Orodispersible tablets rapidly disintegrates with in oral cavity and drug undergoes rapid absorption through oral ...

Albendazole (ABZ) and mebendazole (MBZ) are the 2 most commonly used drugs in the treatment of soil-transmitted helminth infections in humans, but their performance is hampered by low solubility and physicochemical prope...

Objective: To develop a targeted delivery to the fungal affected cells. The present study focus on developing, optimizing, and evaluating a novel Niosomal loaded nail lacquer formulation for increasing the transdermal ...

Background: Paclitaxel, a potent anti-neoplastic agent, finds application in treating various malignancies like breast, ovarian, lung, and pancreatic cancers. However, paclitaxel's hydrophobicity renders it poorly solubl...

Artificial saliva (AS) is an aqueous solution designed to mimic the properties of natural saliva and is widely used in various in vitro studies. This investigation aimed to identify the most frequently selected AS compos...

Amphotericin B (AmB) is a potent, accessible, FDA-approved drug against CL with damaging side effects. While newer lipid formulations have less toxicity, limitations include affordability and cold-chain requirements. CL ...

A wide variety of plant-derived phytochemicals with anthelmintic effects have been described. Most of them have shown activity against parasites in vitro but have not been extensively explored in vivo. The aim of the cur...