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The production, distribution, and consumption of drugs has long been seen as a threat to social and economic development. On the other hand, conditions of unemployment and poverty foster expansion of illegal drug markets...

Background/Aim Second-generation immunomodulating drugs for inflammatory dermatoses have expanded over the past decades. Contraindications and special warnings must be considered before starting any treatment, but identi...

When studying the effects of nicotin on adrenal secretion it was found that the injection of this drug into the adrenal gland produced a marked increase of the epinephrin secretion. In this paper the effects of several o...

Persistent cervical human papillomavirus (HPV) infection is the key biological event underlying high-grade squamous intraepithelial lesions, cervical cancer development, and recurrence risk. Botanical drugs and their bio...

Following prospective registration (PROSPERO CRD42024564275), three databases (PubMed, SCOPUS, Web of Science) were searched for trials reporting the effects of anti-obesity drugs (AODs) (with placebo as control) on card...

Renal transplantation is the most prominent treatment of end-stage renal failure. Unfortunately, acute and chronic rejections and drug toxicities reduce graft survival in the post-transplantation period. An attempt has t...

Abstract The proposed study is an integrated graph-theoretical and statistical model of predictive modeling and ranking of influenza strain drugs based on temperature-based topological indices. Chemical graphs were used ...

ObjectiveTo provide a preliminary understanding of the residues of anticoccidial drugs in eggs in China and to assess the associated dietary exposure risks.MethodsA statistical analysis was performed on the residue data ...

Self-assembly has fascinated many scientists over the past few decades. Rapid advances and widespread interest in the study of this subject has led to the synthesis of an ever-increasing number of elegant and intricate f...

O objetivo deste estudo foi o de analisar um projeto de prevenção de drogas e Aids desenvolvido nas escolas públicas estaduais de São Paulo. A análise foi desenvolvida considerando-se a diversidade e a complexidade ...

The aim of this article is to discuss the relation between the contemporary use and advertising of pharmaceutical drugs based on the so-called culture of consumption. We discuss advertising as a means of strengthening th...

Here we compare the efficacy of anti-obesity drugs alone or combined with exercise training on body weight and exercise capacity of obese patients. Randomized clinical trials that assessed the impact of any anti-obesity ...

ABSTRACT Cancer is driven by genomic lesions and malignancy‐promoting transcriptional programs. In blood cancers, both are often interconnected as lesions frequently affect transcription factor (TF)‐encoding genes. T...

This article reassesses the book Africa and the War on Drugs (2012) and a related special journal issue (2016) in the light of drug market and policy developments since 2012. As part of this reassessment, we question som...

The COVID-19 pandemic prompted several drug repositioning initiatives with the aim to rapidly deliver pharmacological candidates able to reduce SARS-CoV-2 dissemination and mortality. A major issue shared by many of the ...

Abstract The objective of this study was to establish a multi-residue quantitative method for the analysis of anthelmintic and antiprotozoal drugs in various livestock products (beef, pork, and chicken) using ultra-high-...

Gambling disorder or pathological gambling is a psychiatric disorder with severe and wide-ranging consequences for the affected individual and their surroundings. While no pharmacological treatment has yet been officiall...

Liver and kidney, as the core metabolic detoxification organs of human body, rely on specific biofilm barrier and metabolic enzyme system to form metabolic barrier respectively. This metabolic barrier is the key defense ...

Commercial antifungal drugs possess important side effect; being toxicity the main limitation of such compounds. We report here a study of acute toxicity of four well-known commercial antifungal drugs; two of them used...

This study aims to evaluate the criteria and procedures for the selection of antidiabetic and antihypertensive drugs purchased by the public health network of the cities in the Ourinhos Micro-region, Sao Paulo, Brazil....

Therapeutic importance and benefices caused by antineoplastic drugs are unquestionable however unfortunately well-known are their side effects. So, the extensive use and the exposure to multiple agents may be at risk to ...

The aim of this study was to evaluate the utilization of oral hypoglycemic drugs (OH) in a third level public hospital in Rosario (Argentina) in relation with the adherence to them and the blood glucose level (BGL) contr...

Multiple drug administration increases chances of drug interaction, altering the responses of drugs either increasing or decreasing pharmacological effects, or generating a new pharmacological response. Generally drug in...

The solubility behaviour of drugs remains one of the most challenging aspects in formulation development. Solid dispersions (SD) and inclusion complexes (IC) are two of the most promising strategies to improve the oral...