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Human induced pluripotent stem cells (iPSCs) are transforming adoptive cell therapy by combining unlimited self-renewal, broad differentiation potential, and high amenability to genome engineering. These attributes make ...

Abstract Background Electrical stimulation of cell culture systems has shown significant potential benefits, attracting growing interest in bioelectrical research and tissue engineering. However, implementing effective s...

The escalation of ecological degradation, marked by climatic instability, precipitous biodiversity loss, and systemic chemical infiltration, necessitates a shift toward integrated biotechnological intervention. This anal...

Materias / palabras clave: Science: Biology (General)

ABSTRACT Genome engineering plays a crucial role in the rapidly growing fields of metabolic engineering and synthetic biology. Chromosomal integration and stable expression of functional genes or large metabolic pathways...

Materias / palabras clave: Science: Biology (General): Ecology; Technology: Engineering (General). Civil engineering (General): Engineering geology. Rock mechanics. Soil mechanics. Underground construction

Synthetic biology is emerging as a frontier interdisciplinary discipline that is increasingly regarded as a key driver of sustainable innovation in advanced materials. By leveraging the design-build-test-learn (DBTL) cyc...

Abstract Background Chinese hamster ovary (CHO) cells are pivotal in biopharmaceutical production, yet balancing high recombinant protein yield with cell survival remains challenging. While previous studies have targeted...

Abstract Intracerebral hemorrhage (ICH) is a devastating neurological condition with high mortality and morbidity. Despite advancements in medical and surgical treatments, the long-term prognosis of ICH remains poor. Ste...

Abstract Many sulfated polysaccharides (SPSs) possess useful physicochemical properties and biological activities and are widely used in industry. Currently, major SPSs are derived from livestock and marine organisms. To...

Materias / palabras clave: Technology: Engineering (General). Civil engineering (General): Disasters and engineering; Science: Biology (General): Ecology; Science: Physics: Meteorology. Climatology

This study aims to examine the role of exosomes derived from human urine-derived stem cells (hUSCs-Exo) in the in vitro construction of a composite structure comprising hUSCs and a porcine urethral decellularized matrix...

Abstract Chimeric antigen receptor (CAR) T cell therapies have achieved clinical success in autologous treatment of hematological malignancies. However, their broader application remains limited. Beyond the biological ch...

Abstract Background Gas-phase bioprocesses that immobilize microbial cells on solid carriers enable efficient conversion of volatile or poorly water-soluble substrates. Acinetobacter sp. Tol 5 is a highly adhesive bacter...

Abstract The global emergence and spread of infectious diseases highlights the importance of having an easily accessible, decentralized testing modality that is adept at quickly identifying the nucleic acids present in a...

Ganoderic acids (GAs), the major lanostane-type triterpenoids in Ganoderma lucidum (G. lucidum), possess diverse pharmacological activities but are produced at low levels, limiting their applications. Transcriptional reg...

In the biomedical field, polyethylene glycol-based materials demonstrate remarkable positive potential as drug delivery systems, in wound healing, and tissue engineering. It’s known that complex of polyethylene glycol ...

ABSTRACT The cultivation of halophilic microorganisms has been widely reported in liquid and semi-solid media. However, there are few reports on the use of solid fermentation for their cultivation. In the present work, t...

Background: Deep learning has transformed medical imaging by enabling earlier and more accurate disease diagnosis. Lesion and tumor segmentation, essential for analyzing and tracking morphological changes, is commonly do...

Materias / palabras clave: Technology: Electrical engineering. Electronics. Nuclear engineering: Materials of engineering and construction. Mechanics of materials; Science: Biology (General)

Materias / palabras clave: Technology: Electrical engineering. Electronics. Nuclear engineering: Materials of engineering and construction. Mechanics of materials; Science: Biology (General)

Materias / palabras clave: Technology: Electrical engineering. Electronics. Nuclear engineering: Materials of engineering and construction. Mechanics of materials; Science: Biology (General)

Materias / palabras clave: Science: Biology (General): Life; Science: Biology (General): Ecology; Technology: Environmental technology. Sanitary engineering: Environmental pollution