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Abstract Background Uncertainty is an inherent and challenging aspect of medical practice, particularly for first-year residents making the transition from theoretical education to clinical practice. We aimed to identify...

IntroductionCritical thinking is emphasized as an important learning aim in early medical education, yet how students experience learning this capability in practice remains underexplored. Understanding students’ exper...

Although Brazil has experienced substantial immigration from the Middle East and Italy, regions with a higher prevalence of pyrin-associated autoinflammatory diseases, pyrinopathies, remain under-investigated in the coun...

Abstract Background Anti-amyloid monoclonal antibodies are entering clinical practice for early symptomatic Alzheimer’s disease (AD), but European real-world data on feasibility, safety, and biomarker monitoring remain...

The COVID-19 pandemic-related lockdown in recent years resulted in many professionals, such as academics, having to work remotely for months, forcing them to renegotiate the boundaries between work and social life. Prior...

Abstract Background As the global incidence of pediatric Inflammatory Bowel Disease (IBD) rises, so does the complexity of its psychosocial burden. While biomedical protocols for clinical management are robust, the subje...

Abstract Background While Canadian First Nations communities actively participate in sport, cultural, and land-based activities, they face various barriers to physical activity. Despite calls for increased support at all...

BackgroundPhakic intraocular lenses (pIOLs), used to correct high refractive errors, have since been associated with long-term complications including glaucoma and cataract formation. Elevated intraocular pressure (IOP) ...

BackgroundSevere combined immunodeficiency (SCID) is a life-threatening condition that requires urgent medical attention. Newborn screening (NBS) using the T cell receptor excision circle (TREC) assay facilitates early d...

Abstract Dreams are universal yet highly idiosyncratic experiences. While memories and personal concerns are known to influence dream content, how such influences evolve over time and how stable individual traits shape d...

BackgroundDigital health and connected technologies may support better health outcomes among older adults, including those with multiple chronic conditions or low engagement in health behaviors. However, initial experien...

BackgroundCommon variable immunodeficiency (CVID) is diagnosed at ages ≥4 years with hypogammaglobulinemia across more than two immunoglobulin classes, leading to impaired vaccine responses, frequent infectious, autoim...

Background: Clinical education is central to physiotherapy training, yet many students enter their first placements with limited experience in holistic clinical reasoning. The International Classification of Functioning...

First-year university students studying medicine and health sciences must acquire and assimilate significant amounts of physiological knowledge, which can result in tedious, passive rote learning. To address such notions...

First-person accounts of perceptual experience in autism remain underrepresented in psychological research. This exploratory study examined how autistic adults use immersive media to externalize and reflect on perception...

Platform engineering has become the dominant approach to managing developer infrastructure at scale, with industry surveys indicating that 94% of organizations have adopted or plan to adopt dedicated platform teams. Desp...

IntroductionMultiple sclerosis (MS) shows marked female predominance, particularly among women of childbearing age (WCBA, 15–49 years), yet their specific disease burden remains under characterized. Using Global Burden...

Abstract Globally groundwater depletion threatens water security with aquifer storage declining at 300 km³/year. Climate change intensifies flood frequency and magnitude causing agricultural and other losses. Punjab, I...

Abstract Background Myosin heavy chain (MyHC)-related congenital myopathies display variable age of onset and clinical manifestations depending on the mutated isoform. Cardiomyopathy, ophthalmoplegia and primarily proxim...

Abstract Objective Eating disorders (ED) are most prevalent in women of reproductive age. EDs affect fertility, maternal BMI, and obstetric outcomes. During the early postpartum period, women with an ED history are at hi...

Abstract Background Mirogabalin and trimethoprim-sulfamethoxazole (TMP/SMX) are frequently used as supportive purpose during and/or after chemotherapy. Mirogabalin is used to treat neuropathic pain, whereas TMP/SMX is us...

Background: South Africa’s population experiences high rates of gender-based violence (GBV), with primary care emergency centres (ECs) often being the first point of contact for victim-survivors of violence. The abili...

School food programs (SFPs), which may include breakfast, lunch, and snacks, with or without curriculum integration, have tremendous potential to enhance the health and well-being of Canadian children, youth and communit...

Abstract Dengue virus (DENV) transmission in Bolivia has historically been restricted to tropical lowland regions, where the primary vector Ae. aegypti is endemic. In recent years, however, the vector has expanded into h...