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Abstract Background Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by mucosal inflammation, epithelial barrier disruption, and immune dysregulation. Cannabidiol (CBD), a non-psychoactive ph...

The gut–brain axis represents a bidirectional communication pathway influencing mood through microbiota-related mechanisms. This randomized, double-blind, active-controlled pilot trial evaluated the effects of a multi-...

Microbial contamination in animal feed undermines livestock safety and storage stability, driving a critical demand for potent natural preservatives. This study investigated the antimicrobial efficacy of Alquermold Natur...

The intestinal microbiota has been implicated in neurological function through the gut–brain axis, and specific probiotic strains have been proposed to influence neuroactive pathways relevant to sleep. This randomized,...

Abstract Lice and mange represent common ectoparasitic infestations in domestic cats, affecting their health and well-being. The study evaluated the efficacy of a topical formulation containing 12.5% fipronil + 0.83% mox...

Abstract The IL-6 signalling pathway plays a significant role in the progression and development of squamous cell carcinoma (SCC). Bazedoxifene is a potent inhibitor of IL-6R; however, its efficacy is limited by its low ...

ABSTRACT Background Skin cancer is one of the most prevalent malignancies worldwide, characterized by the abnormal growth of skin cells and significant clinical challenges. Conventional treatments—including surgery, ch...

Abstract Despite the extensive use of synthetic and semi-synthetic lipids in nanostructured lipid carrier (NLC) systems, the utilization of Shorea spp. (Illipe butter or tengkawang fat), an indigenous natural solid lipid...

In the present study, the transmission error (TE) behaviour of an identical involute spur gear pair dynamically coupled with an attached subsystem is investigated through numerical modelling. The surrounding mechanical s...

Background: Conventional glass ionomer cement (GIC) is widely used as a restorative base and liner owing to its chemical adhesion to dentine, fluoride release, and favourable biocompatibility. Nevertheless, its intrinsic...

Chandrasekhar’s H ( μ ) function forms the foundation of radiative transfer theory for semi-infinite, isotropically scattering atmospheres under external illumination. However, the classical formulation does not accou...

Artificial saliva (AS) is an aqueous solution designed to mimic the properties of natural saliva and is widely used in various in vitro studies. This investigation aimed to identify the most frequently selected AS compos...

Invasive fungal infections remain a major cause of global morbidity and mortality, with resistance to conventional antifungal agents posing an increasing challenge. Ethosomal nanocarriers have gained attention as effecti...

Abstract Background Naringenin has shown attractive neuroprotective effects; however, it is characterized by low oral bioavailability. Naringenin-loaded nanoparticles (Nar-NPs) were prepared for enhanced delivery, and ...

Abstract Background Skin disorders are widespread, and there is increasing demand for reliable, standardized herbal therapeutics. Kumkumadi Tailam, a classical Ayurvedic polyherbal oil formulation, incorporates several b...

Synthesis of new drugs, their rational design, or isolation from natural sources has decreased, and these facts lead to the use of currently marketed drugs. Some of them, extensively used, show unfavorable properties rel...