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Abstract Background Life expectancy increases, leading to growth in an older population where frailty and comorbidities are more prevalent. Subsequent increased intensive care unit (ICU) treatment results in prolonged re...

BACKGROUND: Frailty is considered highly prevalent in old age and to confer high risk for falls, disability, hospitalization, and mortality. Frailty has been considered synonymous with disability, comorbidity, and other ...

BackgroundFrailty is significantly more prevalent in individuals with Parkinson’s disease (PD) than in general population, yet the underlying neuropathophysiological mechanisms remain poorly understood. This study aime...

Objectives: To analyse the relationship between oral frailty (OF) and cognitive impairment in older adults and explore the association between OF and different domains of cognitive function. Methods: A total of 461 commu...

Abstract Objectives The relationship between metabolic dysregulation and frailty remains incompletely understood. This study examines the association between metabolic dysregulation and frailty in middle-aged and older a...

Abstract Background Frailty is a known predictor of adverse surgical outcomes, yet its influence on functional recovery trajectories in South Asian settings remains underexplored. This study evaluated the association bet...

Abstract Objective Given the increased risk of frailty among middle-aged and older adults with obesity, we aimed to develop and validate a predictive model for incident frailty among adults aged ≥ 45 years with obe...

Abstract Background Oral frailty is a key determinant of older adults’ health, functional independence, and quality of life. However, its core elements and interrelationships lack clear systematic conceptualization, an...

BackgroundFrailty is recognized as an important predictor of postoperative outcomes, yet evidence on the differential association between the 5-factor modified frailty index (mFI-5) and specific postoperative pulmonary c...

ObjectiveExcessive secretion of inflammatory biomarkers exerts adverse effects on muscle strength and function, and is associated with the development and progression of sarcopenia and frailty. For the improvement of inf...

BackgroundFrailty is a complex age-related clinical syndrome characterized by diminished physiological reserve and increased vulnerability to stressors. Cognitive function may be associated with frailty; however, evidenc...

ABSTRACT BACKGROUND: Frailty in older adults is a multifactorial geriatric syndrome associated with inflammation, malnutrition, and hematological decline. Objective and easily applicable laboratory-based indices may com...

IntroductionParkinson’s disease (PD) is the second most common neurodegenerative disorder. The risk of frailty is significantly higher in patients with PD than in age-matched individuals without PD. This study aimed to...

Abstract Background Oral frailty is a significant risk factor for systemic frailty and poor health outcomes in older adults. While oral health care interventions may mitigate this decline, the evidence remains fragmented...

BackgroundFrailty serves as a significant precursor to falls, disability, and mortality. Epidemiological evidence examining the impact of working hours on frailty remains scarce.ObjectiveTo explore the prevalence of frai...

Abstract Background Frailty is strongly associated with adverse outcomes including depression, cognitive decline, falls, and reduced quality of life. Frailty is an important indicator of older individuals’ health statu...

Abstract Objective This study aimed to explore self-perceptions and embodied experiences of different dimensions of frailty among older adults with hip fracture, to complement objective frailty assessment and inform the ...

Christos Kleisiaris,1 Theodora Arida,2 Maria Klesiora,1 Konstantinos Tsaras,1 Maria Malliarou,1 Ioanna V Papathanasiou,1 Theodosios Paralikas,1 Nikolaos Bakalis,3 Mahmoud Ogla Al-Hussami,4 Wafa Hamad Almegewly,5 Savvato ...

ABSTRACT Background and Aims In Ethiopia, glaucoma and related cases account for 5.2% of the irreversible blindness and is the fifth main cause of blindness. The aim of this study was to investigate the time to blindness...

Materias / palabras clave: frailty; lobectomy; modified frailty index; pleural effusion; pneumothorax; postoperative infection

Background Many older people experience Mild Cognitive Impairment (MCI), which may compromise the effectiveness of health promotion programmes.Objectives We explored engagement with behaviour change among participants sc...

Abstract Physical frailty may weaken structural brain integrity (SBI), which may lead to cognitive impairments. In this cross-sectional study, the number of final study participants was 2057 (700 men, 1357 women). The pr...

Managing multiple long-term conditions (MLTCs) is a growing priority for health and social care systems, as MLTCs often lead to frailty and reduced resilience to adverse health events. Behaviour change interventions for ...

Avery Shuei-He Yang,1,2 Hsin-Yu Fan Chiang,1 Daniel Hsiang-Te Tsai,1,2 Albert Tzu-Ming Chuang,1,2 Edward Chia-Cheng Lai1,2 1School of Pharmacy, Institute of Clinical Pharmacy and Pharmaceutical Sciences, College of Medic...