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120 resultados encontrados.

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Genetic Prediction of Sepsis Severity Based on the Detection of MCP-1 Gene Polymorphism in Patients with Acquired Immunological Disorders
Artículo
Acceso abierto Artículo DOAJ
N. Matselski et al · Rockefeller University Press · 2026 · ISSN 3065-8993
Background and AimsAcquired immunodeficiency in patients with hematological oncology is a serious and common complication, significantly impacting prognosis and quality of life. High doses of cytostatic drugs and the mal...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Open Access
Gene Expression of Antioxidant Enzymes in Healthy and Aborted Women
Artículo
Acceso abierto Artículo DOAJ
Yasir A'al-Issa et al · University of Mosul, College of Education for Pure Science · 2025 · ISSN 1812-125X
Gene expression analysis is one of the most important tools for discovering the link between human disorders and the genes that control them. The primary purpose of this study is to identify the gene expression profile o...
LCC TENDOkVkdWNhdGlvbg~~; LCC:Science (General)Idioma eng
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Open Access
Gene Therapy Using Recombinant Adeno-Associated Virus for Leber Congenital Amaurosis Induced by RPE65 Mutation
Artículo
Material complementario disponible Artículo DOAJ
Owliaee I et al · Dove Medical Press · 2026 · ISSN 1177-5483
Iman Owliaee,1 Ali Teimoori,1 Mohammad Shoushtari,2 Ali Shojaeian3 1Department of Medical Virology, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran; 2Department of Virology, Pasteur Institute o...
LCC TENDOk9waHRoYWxtb2xvZ3k~Idioma eng
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Genetic aspects of sleep in humans
Artículo
Acceso abierto Artículo DOAJ
Camila Guindalini et al · Thieme Revinter Publicações Ltda · 2012 · ISSN 1984-0659
Together with the environment, genetic factors can significantly influence sleep and its architecture. Monozygotic twins have greater similarity in terms of latency and duration of sleep cycles than dizygotic twins, in a...
LCC TENDOlBzeWNob2xvZ3k~; TENDOkNvbnNjaW91c25lc3MuIENvZ25pdGlvbg~~Idioma eng
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Open Access
Clinical and Genetic Spectrum of Autoimmune Lymphoproliferative Syndrome (ALPS) and ALPS-Like Disorders in Brazil: Insights from the First Year of the CNE3i National Cohort
Artículo
Material complementario disponible Artículo DOAJ
Marcia Toraiwa Iwashita et al · Rockefeller University Press · 2026 · ISSN 3065-8993
The recognition of disorders of immune dysregulation, particularly those presenting with lymphoproliferation and systemic autoimmunity (International Union of Immunological Societies [IUIS] Group 4.6), has markedly incre...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Haloperidol versus second-generation antipsychotics on the cognitive performance of individuals with schizophrenia and related disorders: pairwise meta-analysis of randomized controlled trials
Artículo
Acceso abierto Artículo DOAJ
Daniel Prates Baldez et al · Associação de Psiquiatria do Rio Grande do Sul · 2025 · ISSN 2238-0019
Abstract Objective Despite previous literature, the superiority of second-generation antipsychotics (SGAs) relative to first-generation antipsychotics – especially haloperidol – on cognitive management in schizophre...
LCC TENDOlBzeWNoaWF0cnk~Idioma eng
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Open Access
Immunogenetic Screening Reveals Hidden Inborn Errors of Immunity in Pediatric Lymphoproliferative Disorders
Artículo
Acceso abierto Artículo DOAJ
Martina Burattin et al · Rockefeller University Press · 2026 · ISSN 3065-8993
Background and AimsPediatric lymphoproliferative disorders (LPD), both malignant and nonmalignant, may conceal underlying inborn errors of immunity (IEI), yet systematic screening is rarely performed. We hypothesized tha...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Open Access
Insulin Resistance Across Cerebrovascular and Related Disorders: Mechanisms, Measurement, Genetics, and Clinical Implications
Artículo
Material complementario disponible Artículo DOAJ
Chen K et al · Dove Medical Press · 2026 · ISSN 1178-2021
Kai Chen,1,* Yiqing Nong,1,* Ying Liu,2 Ziming Ye3 1Department of Neurology, Guangxi Medical University Kaiyuan Langdong Hospital, Nanning, 530023, People’s Republic of China; 2Department of Rehabilitat...
LCC LCC:Neurosciences. Biological psychiatry. Neuropsychiatry; LCC:Neurology. Diseases of the nervous systemIdioma eng
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The Role of TLR4 Gene Polymorphisms in the Development of Severe Sepsis in Oncohematological Patients with Acquired Immunological Disorders
Artículo
Acceso abierto Artículo DOAJ
E. Polyakova et al · Rockefeller University Press · 2026 · ISSN 3065-8993
Background and AimsSepsis is a common complication in patients with hematological malignancies that occurs during chemotherapy treatment, which in turn leads to acquired immunodeficiency. In recent years, increasing atte...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Open Access
Oral health-related quality of life in adult inpatients with psychiatric and/or substance use disorders: a Norwegian cross-sectional study
Artículo
Material complementario disponible Artículo DOAJ
Kristina G. Kantola et al · Frontiers Media S.A · 2026 · ISSN 2673-4842
IntroductionThis study aimed to assess the prevalence and nature of oral health impacts on daily life and examine the relationship between psychiatric symptoms, oral health problems, and oral health related quality of li...
LCC TENDOkRlbnRpc3RyeQ~~Idioma eng
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Analysis of risk factors for tic disorders in children in Hubei region based on liquid chromatography-tandem mass spectrometry
Artículo
Material complementario disponible Artículo DOAJ
Yingchan Hao et al · Frontiers Media S.A · 2026 · ISSN 1662-453X
ObjectiveThis study aims to investigate the correlation between trace element concentrations, 25-hydroxyvitamin D [25(OH)D] levels, and the severity of tic disorders (TD) in children from the Hubei region. Additionally, ...
LCC LCC:Neurosciences. Biological psychiatry. NeuropsychiatryIdioma eng
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Associations Between Reproductive Disorders and Specific Physical, Mental, Personality, and Social Characteristics: A Narrative Review
Artículo
Acceso abierto Artículo DOAJ
Juan J. Tarín et al · Wiley · 2026 · ISSN 2398-8835
ABSTRACT Background and Aims The present review aims to ascertain whether reproductive disorders are associated with specific physical, mental, personality, and social traits. This information may be used to support or r...
LCC LCC:MedicineIdioma eng
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Open Access
Case Report: Where is the boundary between autosomal recessive early-onset Parkinson’s disease and dystonia-parkinsonism: a case of PLA2G6-associated neurodegeneration
Artículo
Acceso abierto Artículo DOAJ
Xiao-Tian Li et al · Frontiers Media S.A · 2026 · ISSN 1662-5161
BackgroundMutations in the PLA2G6 gene cause a spectrum of neurodegenerative disorders, with autosomal recessive early-onset Parkinson’s disease (AREP) and dystonia-parkinsonism (DP) representing the two primary subtyp...
LCC LCC:Neurosciences. Biological psychiatry. NeuropsychiatryIdioma eng
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Open Access
Characterizing the effects of genetic liability to autoimmune conditions on pregnancy outcomes using Mendelian randomization
Artículo
Acceso abierto Artículo DOAJ
Elisabeth Aiton et al · BMC · 2026 · ISSN 1741-7015
Abstract Background Autoimmune conditions are common in women of reproductive age. They are associated with an increased risk of adverse pregnancy outcomes; whether this is causal is unclear. Our aim was to explore the c...
LCC LCC:MedicineIdioma eng
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Open Access
Common mental disorders in mothers vs. infant and obstetric outcomes: a review Transtornos mentais comuns em mães versus desfechos infantis e obstétricos: uma revisão
Artículo
Material complementario disponible Artículo DOAJ
Paula Borba et al · Associação de Psiquiatria do Rio Grande do Sul · 2012 · ISSN 2237-6089
INTRODUCTION: Pregnancy has been shown to increase women’s vulnerability to mental disorders. Common mental disorders (CMDs) have been studied both in the general population and in pregnant vs. non-pregnant women. ...
LCC TENDOlBzeWNoaWF0cnk~Idioma eng
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Differential Analysis of Personality Disorders and Affective Disorders
Artículo
Material complementario disponible Artículo DOAJ
Yuliia Zinchenko · V. N. Karazin Kharkiv National University · 2025 · ISSN 2225-7756
The article considers the problem of differential differences between severe personality disorders and affective spectrum disorders. A comparative analysis of symptoms, behavioral manifestations, and features of the deve...
LCC TENDOlBzeWNob2xvZ3k~Idioma ukr
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Hemophilia in Women: Beyond the Carrier State - Clinical, Genetic, and Diagnostic Challenges
Artículo
Acceso abierto Artículo DOAJ
Sylwia Haba et al · Nicolaus Copernicus University in Toruń · 2026 · ISSN 2450-3118
Background: Hemophilia is a genetic bleeding disorder resulting from a deficiency of specific coagulation factors. The most common forms, hemophilia A and B, are X-linked and mainly affect males, with females usually bei...
LCC TENDOlNwb3J0cw~~; TENDOlNwb3J0cyBtZWRpY2luZQ~~Idioma eng
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Open Access
Prevalence of Abortifacient Disorders in Small Ruminants: a Comprehensive Review
Artículo
Acceso abierto Artículo DOAJ
Abdul Saboor et al · Wright State University · 2024 · ISSN 2309-3854
Abortifacient disorders in small ruminants present a serious problem for livestock farmers, leading to financial losses and lower production rates. This review examines both infectious and non-infectious factors that cau...
LCC TENDOkVudmlyb25tZW50YWwgc2NpZW5jZXM~; TENDOkVjb2xvZ3k~Idioma eng
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Prior stress promotes the generalization of contextual fear memories: Involvement of the gabaergic signaling within the basolateral amygdala complex
Artículo
Acceso abierto Artículo CONICET Digital
Bender, Crhistian Luis et al · Pergamon-Elsevier Science Ltd · 2018 · ISSN 0278-5846
Fear generalization occurs when a response, previously acquired with a threatening stimulus, is transferred to a similar one. However, it could be maladaptive when stimuli that do not represent a real threat are appraise...
Idioma eng
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Open Access
Psychiatric disorders, depression and quality of life in patients with psychogenic non-epileptic seizures and drug resistant epilepsy living in Argentina
Artículo
Material complementario disponible Artículo CONICET Digital
Scévola, Maria Laura et al · W B Saunders Co Ltd · 2021 · ISSN 1059-1311
Objectives: Psychiatric disorders are frequently found in both patients with PNES and DRE, making the differential diagnosis even more complex. The aim of this study was to analyze and compare psychiatric aspects and the...
Idioma eng
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Relationship between psychopathology and binge size in binge eating spectrum disorders
Artículo
Acceso abierto Artículo DOAJ
Carla L. Mourilhe Silva et al · Associação de Psiquiatria do Rio Grande do Sul · 2024 · ISSN 2238-0019
Abstract Objective: Food intake during binge eating episodes (BEE) has been found to be associated with symptoms of depression and anxiety in individuals with eating disorders (EDs). The objective of this study was to e...
LCC TENDOlBzeWNoaWF0cnk~Idioma eng
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Open Access
Shift work disorders: implications and proposed management
Artículo
Acceso abierto Artículo DOAJ
Patrick Rademaker Burke et al · Thieme Revinter Publicações Ltda · 2012 · ISSN 1984-0659
Economic demand has modified the temporal organization of work and established the system of shift work. The inability of the individual worker to maintain an adequate quantity and quality of sleep after a day of shift w...
LCC TENDOlBzeWNob2xvZ3k~; TENDOkNvbnNjaW91c25lc3MuIENvZ25pdGlvbg~~Idioma eng
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Temporomandibular disorders prevalence and associated factors among adolescents in Al-Ahsa, Saudi Arabia: a school-based cross-sectional study
Artículo
Material complementario disponible Artículo DOAJ
Jasem Ahmad H Alburaih et al · BMC · 2026 · ISSN 1472-6831
Abstract Background Temporomandibular disorders (TMDs) are conditions affecting the temporomandibular joint and its surrounding structures, characterized by common clinical symptoms. Therefore, this study aimed to identi...
LCC TENDOkRlbnRpc3RyeQ~~Idioma eng
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The correlation of zinc serum levels and zinc intake with taste disorders in elderly patients at Babatan Public Health Center Bandung
Artículo
Acceso abierto Artículo DOAJ
Rahmatia Djou et al · faculty of dentistry universitas gadjah mada · 2022 · ISSN 2460-0164
Taste disorders, which can be caused by various factors, including deficiency of zinc levels in the body and lack of zinc, generally occur in the elderly. The aim of the study was to analyze the correlation between zinc ...
LCC TENDOkRlbnRpc3RyeQ~~Idioma eng
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Open Access