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Gene expression analysis is one of the most important tools for discovering the link between human disorders and the genes that control them. The primary purpose of this study is to identify the gene expression profile o...

The Gene Expression Omnibus (GEO) project was initiated in response to the growing demand for a public repository for high-throughput gene expression data. GEO provides a flexible and open design that facilitates submiss...

The purpose of this study was to classify breast carcinomas based on variations in gene expression patterns derived from cDNA microarrays and to correlate tumor characteristics to clinical outcome. A total of 85 cDNA mic...

Abstract We hypothesized that supplementing finishing diets with palm oil would promote adipogenic gene expression but depress stearoyl-CoA desaturase (SCD) gene expression in intramuscular (i.m.) adipose tissues of Hanw...

Summary This study was designed to evaluate the quality and viability of bovine embryos produced by in vitro fertilization (IVF), after intracytoplasmic injection of pCX-EGFP-liposome complexes or pBCKIP2.8-liposome comp...

Abstract Background In photosynthetic eukaryotes of the green lineage, the expression of the chloroplast genome is mainly regulated post-transcriptionally, by RNA-binding proteins encoded in the nuclear genome termed org...

Voltage-gated calcium channel (Cav)  subunits are auxiliary subunits to Cavs. Recent reports show Cavsubunits may enter the nucleus and suggest a role in transcriptional regulation, but the physiological rele-vance...

Sugars are key constituents that affect quality of grape berries, and consequently the grape metabolic profile relevant to wine?s industry. However, enzymes and transporter genes expression involved in sugar transport at...

Abstract Although intravenous lipid emulsions are routinely administered to preterm infants, their specific effects on skeletal muscle development remain unclear. In this study, a soybean oil‐based lipid emulsion (Intr...

Abstract Background Heavy metal pollution, particularly cadmium (Cd), poses a significant threat to the environment, human health and plant growth. Taurine is an amino acid with antioxidant properties. The effect of taur...

Abstract Objective Thyroid-stimulating hormone beta subunit (TSHB) gene, a member of the glycoprotein hormone beta subunit family, has been detected in ovarian tissues and granulosa cells (GCs) of several species, sugges...

Abstract Aim This study aimed to evaluate the effect of quercetin on osteogenic gene expression in lipopolysaccharide (LPS) stimulated human periodontal ligament cells (hPDLCs) under in vitro conditions. Materials and me...

The pathogenesis of Plasmodium falciparum malaria is linked to the variant surface antigen PfEMP1, which mediates tethering of infected erythrocytes to the host endothelium and is encoded by approximately 60 var genes pe...

Abstract Transcriptional regulation, critical for cellular differentiation and adaptation to environmental changes, involves coordinated interactions among DNA sequences, regulatory proteins, and chromatin architecture. ...

The most common adult primary brain tumor, glioblastoma (GBM), is characterized by fifteen months median patient survival and has no clear etiology. We and others have identified the presence of human cytomegalovirus (HC...

Tremendous amount of RNA sequencing data have been produced by large consortium projects such as TCGA and GTEx, creating new opportunities for data mining and deeper understanding of gene functions. While certain existin...

Although cancer classification has improved over the past 30 years, there has been no general approach for identifying new cancer classes (class discovery) or for assigning tumors to known classes (class prediction). Her...

We have designed a system for targeted gene expression that allows the selective activation of any cloned gene in a wide variety of tissue- and cell-specific patterns. The gene encoding the yeast transcriptional activato...

A high-capacity system was developed to monitor the expression of many genes in parallel. Microarrays prepared by high-speed robotic printing of complementary DNAs on glass were used for quantitative expression measureme...

SUMMARY: It is expected that emerging digital gene expression (DGE) technologies will overtake microarray technologies in the near future for many functional genomics applications. One of the fundamental data analysis ta...

ABSTRACT Tibetan pigs are characterized by significant phenotypic differences relative to lowland pigs. Our previous study demonstrated that the genes CRYAB and CTGF were differentially expressed in heart tissues between...

BackgroundWe have developed a mouse model of Parenteral Nutrition Associated Cholestasis (PNAC) in which combining intestinal inflammation and PN infusion results in cholestasis, hepatic macrophage activation, and transc...

Grain sorghum [Sorghum bicolor (L) moench] exhibits intraspecificvariability for the rate of dormancy release and pre-harvest sprouting behavior. Two inbred lines with contrasting sprouting response were compared: IS9530...

Objective: Ceruloplasmin (Cp) is a copper-binding protein expressed in several tissues that plays distinct functions depending on the physiological context. Recently, increased ceruloplasmin expression in cavernosal tiss...